(Q39381084)

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The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22411134%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22411134%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Patrick E. Macdonald

14

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Europe PubMed Central

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25 January 2020

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X Q Dai

1

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25 January 2020

J E Manning Fox

2

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25 January 2020

D Chikvashvili

3

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25 January 2020

M Casimir

4

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25 January 2020

G Plummer

5

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25 January 2020

C Hajmrle

6

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25 January 2020

A F Spigelman

7

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25 January 2020

T Kin

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22411134%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

D Singer-Lahat

9

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25 January 2020

Y Kang

10

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25 January 2020

A M J Shapiro

11

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25 January 2020

H Y Gaisano

12

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25 January 2020

I Lotan

13

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25 January 2020

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13 March 2012

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25 January 2020

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22411134%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

55

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25 January 2020

6

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25 January 2020

1709-1720

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Europe PubMed Central

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25 January 2020

Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Gating modifier peptides as probes of pancreatic beta-cell physiology

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Delayed-rectifier (KV2.1) regulation of pancreatic beta-cell calcium responses to glucose: inhibitor specificity and modeling

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Biophysical and pharmacological properties of the voltage-gated potassium current of human pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

A biophysical model of electrical activity in human β-cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Molecular determinants of regulated exocytosis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Functional and physical coupling of voltage-sensitive calcium channels with exocytotic proteins: ramifications for the secretion mechanism

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Syntaxin 1A Modulates the Voltage-gated L-type Calcium Channel (Cav1.2) in a Cooperative Manner

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Syntaxin-1A binds the nucleotide-binding folds of sulphonylurea receptor 1 to regulate the KATP channel

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

H3 domain of syntaxin 1A inhibits KATP channels by its actions on the sulfonylurea receptor 1 nucleotide-binding folds-1 and -2.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Synaptosome-associated protein of 25 kilodaltons modulates Kv2.1 voltage-dependent K(+) channels in neuroendocrine islet beta-cells through an interaction with the channel N terminus

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

K+ channel facilitation of exocytosis by dynamic interaction with syntaxin

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Voltage-gated potassium channel as a facilitator of exocytosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Non-conducting function of the Kv2.1 channel enables it to recruit vesicles for release in neuroendocrine and nerve cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Direct interaction of endogenous Kv channels with syntaxin enhances exocytosis by neuroendocrine cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Regulation of glucagon release in mouse -cells by KATP channels and inactivation of TTX-sensitive Na+ channels.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Kv2.1 channel activation and inactivation is influenced by physical interactions of both syntaxin 1A and the syntaxin 1A/soluble N-ethylmaleimide-sensitive factor-25 (t-SNARE) complex with the C terminus of the channel

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Direct interaction of target SNAREs with the Kv2.1 channel. Modal regulation of channel activation and inactivation gating

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Interactions of presynaptic Ca2+ channels and snare proteins in neurotransmitter release

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Expression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Expression of voltage-gated potassium channels in human and rhesus pancreatic islets

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Inhibition of cholesterol biosynthesis impairs insulin secretion and voltage-gated calcium channel function in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Glucose-sensing mechanisms in pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Insulin vesicle release: walk, kiss, pause ... then run.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Regulation of resident and newcomer insulin granules by calcium and SNARE proteins

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Kiss-and-run exocytosis and fusion pores of secretory vesicles in human beta-cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

The ins and outs of secretion from pancreatic beta-cells: control of single-vesicle exo- and endocytosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2512-6

21 January 2018

Large dense-core vesicle exocytosis in pancreatic $beta;-cells monitored by capacitance measurements

1 reference

https://pubmed.ncbi.nlm.nih.gov/22411134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Syntaxin 1A binds to the cytoplasmic C terminus of Kv2.1 to regulate channel gating and trafficking

1 reference

https://pubmed.ncbi.nlm.nih.gov/22411134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22411134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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