(Q39387987)

11 September 2017

T cells redirected by a CD3ζ chimeric antigen receptor can establish self-antigen-specific tumour protection in the long term (English)

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11 September 2017

M Chmielewski

1

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11 September 2017

G Rappl

series ordinal

2

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11 September 2017

A A Hombach

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3

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11 September 2017

H Abken

series ordinal

4

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11 September 2017

1 March 2012

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11 September 2017

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11 September 2017

20

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11 September 2017

177-186

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11 September 2017

2

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https://scigraph.springernature.com/pub.10.1038/gt.2012.21

11 September 2017

0 references

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The T-body approach: redirecting T cells with antibody specificity

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Costimulation tunes tumor-specific activation of redirected T cells in adoptive immunotherapy

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CARs on track in the clinic

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Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor

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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

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Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy

21 January 2018

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Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

21 January 2018

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T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

21 January 2018

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Sustained antigen-specific antitumor recall response mediated by gene-modified CD4+ T helper-1 and CD8+ T cells.

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Tumor ablation by gene-modified T cells in the absence of autoimmunity.

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A chimeric receptor that selectively targets membrane-bound carcinoembryonic antigen (mCEA) in the presence of soluble CEA.

21 January 2018

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CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients

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Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy.

21 January 2018

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TCR gene therapy of spontaneous prostate carcinoma requires in vivo T cell activation.

21 January 2018

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Adoptive transfer of gene-engineered CD4+ helper T cells induces potent primary and secondary tumor rejection

21 January 2018

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Generation and targeting of human tumor-specific Tc1 and Th1 cells transduced with a lentivirus containing a chimeric immunoglobulin T-cell receptor

21 January 2018

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Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15.

21 January 2018

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IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression

21 January 2018

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Molecular cloning of a cDNA coding biliary glycoprotein I: primary structure of a glycoprotein immunologically crossreactive with carcinoembryonic antigen

21 January 2018

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Eradication of established tumors by CD8+ T cell adoptive immunotherapy

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Dendritic cells pulsed with an anti-idiotype antibody mimicking carcinoembryonic antigen (CEA) can reverse immunological tolerance to CEA and induce antitumor immunity in CEA transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.21

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/GT.2012.21

1 reference

11 September 2017

1 reference