(Q39391912)

11 September 2017

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title

Clinical pharmacokinetics of sulphasalazine, its metabolites and other prodrugs of 5-aminosalicylic acid (English)

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11 September 2017

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U Klotz

1

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11 September 2017

publication date

1 July 1985

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Clinical Pharmacokinetics

11 September 2017

published in

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11 September 2017

volume

10

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11 September 2017

issue

4

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11 September 2017

page(s)

285-302

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Kinetics of the Binding of Salicylazosulfapyridine to Human Serum Albumin

11 September 2017

cites work

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12 December 2020

Kinetics of 5-aminosalicylic acid after jejunal instillation in man.

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12 December 2020

Placental and mammary transfer of sulphasalazine

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12 December 2020

Distribution and metabolism of salicyl-azo-sulfapyridine. I. A study with C-14-5-amino-salicylic acid

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12 December 2020

Salivary excretion and pharmacokinetics of sulfapyridine after sulfasalazine

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12 December 2020

Sulphasalazine and male infertility: reversibility and possible mechanism

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12 December 2020

Distribution and metabolism of salicyl-azo-sulfapyridine. II. A study with S35-salicyl-azo-sulfapyridine and S35-sulfapyridine

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12 December 2020

Sulfasalazine. Pharmacology, clinical use, toxicity, and related new drug development

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12 December 2020

Treatment of Crohn's disease with peroral 5-aminosalicylic acid

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12 December 2020

Pathophysiological and disease-induced changes in drug distribution volume: pharmacokinetic implications

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12 December 2020

Placental Transfer of Sulphasalazine and Sulphapyridine and Some of Its Metabolites

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12 December 2020

Treatment of ulcerative colitis with high-dose 5-aminosalicylic acid enemas

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12 December 2020

Tissue and bacterial splitting of sulphasalazine

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12 December 2020

High-performance liquid chromatographic determination of aminosalicylate, sulfapyridine and their metabolites. Its application for pharmacokinetic studies with salicylazosulfapyridine in man

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12 December 2020

The effect of topical N-acetyl-5-aminosalicylic acid in ulcerative colitis

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12 December 2020

The metabolism of salicylazosulphapyridine in ulcerative colitis. I. The relationship between metabolites and the response to treatment in inpatients

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12 December 2020

Azo reduction of sulphasalazine in healthy volunteers

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12 December 2020

Studies of two novel sulfasalazine analogs, ipsalazide and balsalazide

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12 December 2020

Therapeutic Efficacy of Sulfasalazine and Its Metabolites in Patients with Ulcerative Colitis and Crohn's Disease

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12 December 2020

Is Plasma Level Monitoring of Sulfasalazine Indicated in the Treatment of Crohnʼs Disease or Ulcerative Colitis?

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12 December 2020

A stable isotope method for the quantification of N-acetyl-5-aminosalicylic acid in plasma and urine

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12 December 2020

Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine

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12 December 2020

Crohn's disease: drug therapy, diet or surgery?

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12 December 2020

Distribution studies of salicylazosulfapyridine and its metabolites

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12 December 2020

Distribution and metabolism in healthy volunteers of disodium azodisalicylate, a potential therapeutic agent for ulcerative colitis

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12 December 2020

The role of the colon in the metabolism of salicylazosulphapyridine

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12 December 2020

Influence of intestinal transit time on azo-reduction of salicylazosulphapyridine (Salazopyrin)

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12 December 2020

The effect of the acetylator phenotype on the metabolism of sulphasalazine in man

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12 December 2020

Acetylator phenotype and adverse effects of sulphasalazine in healthy subjects

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12 December 2020

Circulating levels of sulphasalazine and its metabolites and their relation to the clinical efficacy of the drug in ulcerative colitis

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12 December 2020

Maternal absorption and placental transfer of sulfasalazine

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12 December 2020

A new slow-release form of 5-aminosalicylic acid for the oral treatment of inflammatory bowel disease. Biopharmaceutic and clinical pharmacokinetic characteristics

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12 December 2020

The role of intestinal bacteria in the metabolism of salicylazosulfapyridine

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12 December 2020

The disposition and metabolism of sulphasalazine (salicylazosulphapyridine) in man

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12 December 2020

Colonic azodisalicylate metabolism determined by in vivo dialysis in healthy volunteers and patients with ulcerative colitis

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12 December 2020

Sulfapyridine metabolites in children with inflammatory bowel disease receiving sulfasalazine

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12 December 2020

Capacity-limited gut wall metabolism of 5-aminosalicylic acid, a therapeutically active metabolite of sulfasalazine, in rats

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12 December 2020

Specific measurement of 5-aminosalicylic acid and its acetylated metabolite in human bile

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12 December 2020

Absorption, metabolism, and excretion of salicylazosulfapyridine in man

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12 December 2020

Is N-acetylation of 5-aminosalicylic acid reversible in man?

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12 December 2020

Further studies of sulphasalazine metabolism in the treatment of ulcerative colitis

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12 December 2020

Salicylazobenzoic acid in ulcerative colitis

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12 December 2020

Disposition of salicylazosulfapyridine (Azulfidine) and metabolites in human breast milk

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12 December 2020

Absorption and excretion of azodisal sodium and its metabolites in man after rectal administration of a single 2-g dose

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12 December 2020

An experiment to determine the active therapeutic moiety of sulphasalazine

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12 December 2020

Disposition of 5-aminosalicylic acid, the active metabolite of sulphasalazine, in man

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12 December 2020

Small bowel absorption of sulfasalazine and its hepatic metabolism in human beings, cats, and rats

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12 December 2020

Retrograde Colonic Spread of Sulphasalazine Enemas

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12 December 2020

Azo reduction of salicyl-azo-sulphapyridine in germ-free and conventional rats

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12 December 2020

Sulfasalazine. Adverse effects and desensitization

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12 December 2020

National Cooperative Crohn's Disease Study: adverse reactions to study drugs

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12 December 2020

Clinical Pharmacokinetics of Sulphasalazine

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12 December 2020

Sulphasalazine treatment during breast feeding

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12 December 2020

Sulfasalazine metabolite pharmacokinetics in pediatric patients with inflammatory bowel disease: effects of disease activity, acetylator phenotype, and age

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12 December 2020

Metabolism of salicylazosulfapyridine in healthy subjects and in patients with ulcerative colitis. Effects of colectomy and of phenobarbital

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12 December 2020

Analysis of N4-trideuteroacetylsulphamerazine and its metabolites sulphamerazine and N4-acetylsulphamerazine in man by means of high-performance liquid chromatography and mass spectrometry

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12 December 2020

5-Aminosalicylic acid enemas in patients with active ulcerative colitis. Influence of acidity on the kinetic pattern

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12 December 2020

Some physico-chemical properties of salicylazosulphapyridine, including its solubility, protolytic constants and general spectrochemical and polarographic behaviour

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12 December 2020

Relative Systemic Availability of Sulfapyridine from Commercial Enteric-Coated and Uncoated Sulfasalazine Tablets

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12 December 2020

Ulcerative colitis and Crohn's colitis: differential diagnosis and treatment

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12 December 2020

5-Aminosalicylic acid in serum and urine after administration by enema to patients with colitis

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12 December 2020

Absorption and excretion of a single 1-g dose of azodisal sodium in subjects with ileostomy

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12 December 2020

Maintenance of remission in ulcerative colitis with oral preparation of 5-aminosalicylic acid

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12 December 2020

A comparison of serum concentrations of sulphasalazine and some of its metabolites after therapy by the oral or rectal route

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12 December 2020

Colonic release of 5-amino salicylic acid from an oral preparation in active ulcerative colitis

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12 December 2020

10.2165/00003088-198510040-00001

Identifiers

DOI

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Dimensions Publication ID

11 September 2017

1033987194

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