(Q39409318)

English

Immunosenescence: the Role of Aging in the Predisposition to Neuro-Infectious Complications Arising from the Treatment of Multiple Sclerosis

scientific article published on August 2017

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scholarly article

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Europe PubMed Central

11 September 2017

1 reference

Europe PubMed Central

Immunosenescence: the Role of Aging in the Predisposition to Neuro-Infectious Complications Arising from the Treatment of Multiple Sclerosis (English)

1 reference

Europe PubMed Central

11 September 2017

multiple sclerosis

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author name string

Elena Grebenciucova

1

1 reference

Europe PubMed Central

11 September 2017

Joseph R Berger

2

1 reference

Europe PubMed Central

11 September 2017

publication date

1 August 2017

1 reference

Europe PubMed Central

11 September 2017

Current Neurology and Neuroscience Reports

1 reference

Europe PubMed Central

11 September 2017

17

1 reference

Europe PubMed Central

11 September 2017

8

1 reference

Europe PubMed Central

11 September 2017

61

1 reference

Europe PubMed Central

11 September 2017

https://scigraph.springernature.com/pub.10.1007/s11910-017-0771-9

0 references

Natalizumab-Related Progressive Multifocal Leukoencephalopathy in Multiple Sclerosis: Findings from an Italian Independent Registry

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Predictors of survival and functional outcomes in natalizumab-associated progressive multifocal leukoencephalopathy

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Natalizumab-related PML 2 weeks after negative anti-JCV antibody assay

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Progressive Multifocal Leukoencephalopathy in a HIV Negative, Immunocompetent Patient.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Progressive multifocal leukoencephalopathy in a patient without apparent immunosuppression

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Progressive multifocal leukoencephalopathy in a 62-year-old immunocompetent woman

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Progressive multifocal leukoencephalopathy in an immunocompetent patient?

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Progressive multifocal leukoencephalopathy in an immunocompetent patient.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Progressive multifocal leucoencephalopathy in an immunocompetent patient with favourable outcome. A case report

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Immunologic mechanisms of fingolimod and the role of immunosenescence in the risk of cryptococcal infection: A case report and review of literature

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Natural history of multiple sclerosis: a unifying concept

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

T-cell response against varicella-zoster virus in fingolimod-treated MS patients

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Herpes simplex virus-1 and varicella-zoster virus latency in ganglia

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Gender difference in the incidence of shingles.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Reduction of CD8(+) T lymphocytes in multiple sclerosis patients treated with dimethyl fumarate

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Key role of T cell defects in age-related vulnerability to West Nile virus

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Chronic herpesvirus reactivation occurs in aging

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

The involution of the ageing human thymic epithelium is independent of puberty. A morphometric study

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Naive T cells are maintained by thymic output in early ages but by proliferation without phenotypic change after age twenty.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Age-related deregulation of naive T cell homeostasis in elderly humans

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

CD4+ and CD8+ T lymphocyte regeneration after anti-retroviral therapy in HIV-1-infected children and adult patients

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Generation of functional thymocytes in the human adult.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

The effect of age on thymic function

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

The influence of age on T cell generation and TCR diversity

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Thymic involution and proliferative T-cell responses in multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Age-related changes in CD8 T cell homeostasis and immunity to infection

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

T cell exhaustion

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Are senescence and exhaustion intertwined or unrelated processes that compromise immunity?

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Age-related impaired type 1 T cell responses to influenza: reduced activation ex vivo, decreased expansion in CTL culture in vitro, and blunted response to influenza vaccination in vivo in the elderly

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Increased apoptosis, curtailed expansion and incomplete differentiation of CD8+ T cells combine to decrease clearance of L. monocytogenes in old mice

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Age-related decrease in TCR repertoire diversity measured with deep and normalized sequence profiling

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Diversity and clonal selection in the human T-cell repertoire

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Age-related differences in polyfunctional T cell responses

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

The role of CD8+ T-cell replicative senescence in human aging

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Reduced naïve CD8(+) T-cell priming efficacy in elderly adults

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Understanding immunosenescence to improve responses to vaccines

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Low Thymic Activity and Dendritic Cell Numbers Are Associated with the Immune Response to Primary Viral Infection in Elderly Humans.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Immune regulation by CD40 and its ligand GP39.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Higher frequency of regulatory T cells in the elderly and increased suppressive activity in neurodegeneration.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Aging of the CD4 T Cell Compartment

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

CD28(-)CD8(+) T cells do not contain unique clonotypes and are therefore dispensable

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

CD28(-) T cells: their role in the age-associated decline of immune function

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Expansion of cytotoxic CD8+ CD28- T cells in healthy ageing people, including centenarians.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Cytomegalovirus Infection and Memory T Cell Inflation

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Immunological memory and late onset autoimmunity

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8+ T cells in aged mice

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Age-Associated Failure To Adjust Type I IFN Receptor Signaling Thresholds after T Cell Activation

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Hallmarks of Tissue-Resident Lymphocytes

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Emerging concepts in tissue-resident T cells: lessons from humans

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Nuclear envelope rupture and repair during cancer cell migration.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Motif module map reveals enforcement of aging by continual NF-kappaB activity

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Immunosenescence: what does it mean to health outcomes in older adults?

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

The ageing B cell population: composition and function

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Cell intrinsic alterations underlie hematopoietic stem cell aging.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

B-cell diversity decreases in old age and is correlated with poor health status

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Aging affects human B cell responses

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Diverse effect of inflammatory markers on insulin resistance and insulin-resistance syndrome in the elderly

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Gene expression analysis of whole blood, peripheral blood mononuclear cells, and lymphoblastoid cell lines from the Framingham Heart Study

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Immunosenescence of human natural killer cells

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Distribution and lytic activity of NK cell subsets in the elderly

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

NK phenotypic markers and IL2 response in NK cells from elderly people.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Immunological biomarkers of ageing in man: changes in both innate and adaptive immunity are associated with health and longevity

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

The value of neutrophil and lymphocyte count in frail older women

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Inflamm-aging. An evolutionary perspective on immunosenescence

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Nod-like proteins in immunity, inflammation and disease

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

N-glycomic biomarkers of biological aging and longevity: a link with inflammaging

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Circulating mitochondrial DAMPs cause inflammatory responses to injury

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adults

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Cellular senescence: when bad things happen to good cells

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Serum levels of interleukin-6 and C-reactive protein correlate with body mass index across the broad range of obesity

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Late-onset multiple sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

An Immune Risk Phenotype, Cognitive Impairment, and Survival in Very Late Life: Impact of Allostatic Load in Swedish Octogenarian and Nonagenarian Humans

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

The immune risk phenotype is associated with IL-6 in the terminal decline stage: Findings from the Swedish NONA immune longitudinal study of very late life functioning

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

A High Plasma Concentration of TNF- Is Associated With Dementia in Centenarians

1 reference

https://api.crossref.org/works/10.1007%2FS11910-017-0771-9

21 January 2018

The senescence-associated secretory phenotype: the dark side of tumor suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Varicella-zoster virus human ganglionic latency: a current summary

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunophenotypic analysis of hematogones (B-lymphocyte precursors) in 662 consecutive bone marrow specimens by 4-color flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ageing and immunity: addressing immune senescence to ensure healthy ageing

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Menopause and aging: changes in the immune system--a review.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fat tissue, aging, and cellular senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimethyl fumarate-associated lymphopenia: Risk factors and clinical significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The incidence of herpes zoster

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased cytokine production in mononuclear cells of healthy elderly people

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive multifocal leukoencephalopathy in an immunocompetent Taiwanese patient.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in lymphocyte subsets, interleukin 2, and soluble interleukin 2 receptor in old and very old age

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for “inflamm-aging”

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B cell precursors are decreased in senescent BALB/c mice, but retain normal mitotic activity in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural killer cells in the late decades of human life

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Finding Balance: T cell Regulatory Receptor Expression during Aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of dimethyl fumarate (Tecfidera™) on lymphocyte counts: A potential contributor to progressive multifocal leukoencephalopathy risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The network and the remodeling theories of aging: historical background and new perspectives

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell responses are better correlates of vaccine protection in the elderly

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered CD4+/CD8+ T-cell ratios in cerebrospinal fluid of natalizumab-treated patients with multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/28669032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11910-017-0771-9

1 reference

Europe PubMed Central

11 September 2017

release_xte45fguifhabe5encynqa2nem

1 reference

https://api.fatcat.wiki/v0/release/xte45fguifhabe5encynqa2nem

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

11 September 2017

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