(Q39418429)

11 September 2017

title

Novel anti-ErbB3 monoclonal antibodies show therapeutic efficacy in xenografted and spontaneous mouse tumors (English)

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11 September 2017

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12

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11 September 2017

Luigi Aurisicchio

1

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11 September 2017

Emanuele Marra

2

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11 September 2017

Laura Luberto

3

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11 September 2017

Fabrizio Carlomosti

4

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11 September 2017

Claudia De Vitis

5

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11 September 2017

Alessia Noto

6

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11 September 2017

Zeynep Gunes

7

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11 September 2017

Giuseppe Roscilli

8

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11 September 2017

Giuseppe Mesiti

9

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11 September 2017

Rita Mancini

10

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11 September 2017

Maurizio Alimandi

11

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11 September 2017

publication date

1 October 2012

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Journal of Cellular Physiology

11 September 2017

published in

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11 September 2017

volume

227

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11 September 2017

issue

10

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11 September 2017

page(s)

3381-3388

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Epidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB2 and ErbB3 receptors

11 September 2017

cites work

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Feedback inhibition by RALT controls signal output by the ErbB network

21 January 2018

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Gene expression analysis of immune-mediated arrest of tumorigenesis in a transgenic mouse model of HER-2/neu-positive basal-like mammary carcinoma

21 January 2018

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Patented cancer vaccines: the promising leads

21 January 2018

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Treatment of mammary carcinomas in HER-2 transgenic mice through combination of genetic vaccine and an agonist of Toll-like receptor 9.

21 January 2018

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PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells

21 January 2018

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Interleukin 12-mediated prevention of spontaneous mammary adenocarcinomas in two lines of Her-2/neu transgenic mice.

21 January 2018

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A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling

21 January 2018

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Heregulin activation of extracellular acidification in mammary carcinoma cells is associated with expression of HER2 and HER3.

21 January 2018

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Therapeutic vaccination halts disease progression in BALB-neuT mice: the amplitude of elicited immune response is predictive of vaccine efficacy.

21 January 2018

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The deaf and the dumb: the biology of ErbB-2 and ErbB-3

21 January 2018

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Inhibition of N-linked glycosylation disrupts receptor tyrosine kinase signaling in tumor cells

21 January 2018

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Antiapoptotic small interfering RNA as potent adjuvant of DNA vaccination in a mouse mammary tumor model.

21 January 2018

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The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

21 January 2018

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MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

21 January 2018

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Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

21 January 2018

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

21 January 2018

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The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

21 January 2018

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Targeting HER proteins in cancer therapy and the role of the non-target HER3.

21 January 2018

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Oligomers of ERBB3 have two distinct interfaces that differ in their sensitivity to disruption by heregulin.

21 January 2018

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Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells.

21 January 2018

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Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis

21 January 2018

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Ligand-induced ErbB receptor dimerization

21 January 2018

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Cell signaling by receptor tyrosine kinases

21 January 2018

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Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA

21 January 2018

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Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

21 January 2018

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Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

21 January 2018

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Efficient and regulated erythropoietin production by naked DNA injection and muscle electroporation

21 January 2018

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DNA vaccination against rat her-2/Neu p185 more effectively inhibits carcinogenesis than transplantable carcinomas in transgenic BALB/c mice.

21 January 2018

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Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis.

21 January 2018

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An ErbB3 antibody, MM-121, is active in cancers with ligand-dependent activation

21 January 2018

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Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

21 January 2018

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PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer

21 January 2018

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

21 January 2018

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Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function

21 January 2018

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Elevated expression of erbB3 confers paclitaxel resistance in erbB2-overexpressing breast cancer cells via upregulation of Survivin

21 January 2018

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Phosphatidylinositol 3-kinase mediates bronchioalveolar stem cell expansion in mouse models of oncogenic K-ras-induced lung cancer

21 January 2018

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In vivo DNA gene electro-transfer: a systematic analysis of different electrical parameters

21 January 2018

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ErbB receptors: from oncogenes to targeted cancer therapies

21 January 2018

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Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.24037

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11 September 2017

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