(Q39436579)

12 September 2017

title

BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers (English)

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12 September 2017

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D Tkocz

1

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12 September 2017

N T Crawford

2

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12 September 2017

N E Buckley

3

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12 September 2017

F B Berry

4

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12 September 2017

R D Kennedy

5

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12 September 2017

J J Gorski

6

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12 September 2017

D P Harkin

7

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12 September 2017

P B Mullan

8

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12 September 2017

language of work or name

English

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publication date

28 November 2011

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12 September 2017

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12 September 2017

volume

31

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12 September 2017

issue

32

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12 September 2017

page(s)

3667-3678

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Expression of Forkhead-box protein A1, a marker of luminal A type breast cancer, parallels low Oncotype DX 21-gene recurrence scores.

12 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.531

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BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

21 January 2018

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Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors.

21 January 2018

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Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

21 January 2018

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FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A

21 January 2018

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Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment

21 January 2018

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Cell type-specific DNA methylation patterns in the human breast

21 January 2018

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BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

21 January 2018

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The DeltaNp63 proteins are key allies of BRCA1 in the prevention of basal-like breast cancer

21 January 2018

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BRCA1 regulates IFN-gamma signaling through a mechanism involving the type I IFNs

21 January 2018

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Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells

21 January 2018

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DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response

21 January 2018

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GATA3 inhibits breast cancer growth and pulmonary breast cancer metastasis

21 January 2018

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

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Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

21 January 2018

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β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation

21 January 2018

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BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer

21 January 2018

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The evolution of Fox genes and their role in development and disease

21 January 2018

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Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.

21 January 2018

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Autocrine TGF-β protects breast cancer cells from apoptosis through reduction of BH3-only protein, Bim.

21 January 2018

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The molecular portraits of breast tumors are conserved across microarray platforms

21 January 2018

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Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer

21 January 2018

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21 January 2018

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GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

21 January 2018

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GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland

21 January 2018

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Front-line treatment of metastatic breast cancer with docetaxel and epirubicin: a multicenter dose-escalation study. The Greek Breast Cancer Cooperative Group (GBCCG).

21 January 2018

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Cytokeratin 5/14-positive breast cancer: true basal phenotype confined to BRCA1 tumors

21 January 2018

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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

21 January 2018

1 reference

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Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers

21 January 2018

1 reference

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Mesenchymal/stromal gene expression signature relates to basal-like breast cancers, identifies bone metastasis and predicts resistance to therapies

21 January 2018

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.531

BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells

21 January 2018

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

21 January 2018

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Distinctive gene expression patterns in human mammary epithelial cells and breast cancers

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.531

FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.531

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.531

Repeated observation of breast tumor subtypes in independent gene expression data sets

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.531

Repression of mammary stem/progenitor cells by p53 is mediated by Notch and separable from apoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.531

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.531

Hallmarks of 'BRCAness' in sporadic cancers

21 January 2018

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Mutation of GATA3 in human breast tumors

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.531

BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.531

GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.531

Higher levels of GATA3 predict better survival in women with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.531

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.531

Epithelial (E-) and placental (P-) cadherin cell adhesion molecule expression in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.531

Prognostic significance of BRCA1 expression in Japanese sporadic breast carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.531

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.531

1 reference

12 September 2017

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