(Q39439183)

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Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients.

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17 January 2020

Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients (English)

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17 January 2020

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Alfred S. Cheng

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K F Cheung

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17 January 2020

X Ma

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17 January 2020

J Zhao

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M Y Y Go

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17 January 2020

B Shen

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J Ying

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H-F Kung

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J Yu

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21 November 2011

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17 January 2020

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17 January 2020

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17 January 2020

3419-3430

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17 January 2020

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17 January 2020

https://scigraph.springernature.com/pub.10.1038/onc.2011.511

0 references

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

A novel B-cell lineage-specific transcription factor present at early but not late stages of differentiation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

The PAX5 oncogene is expressed in N-type neuroblastoma cells and increases tumorigenicity of a S-type cell line.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

The MET receptor tyrosine kinase in invasion and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Deregulation of PAX-5 by translocation of the Emu enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Pax5 maintains cellular identity by repressing gene expression throughout B cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Changing views of the role of matrix metalloproteinases in metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Pax5: the guardian of B cell identity and function

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Aberrant CpG Island Hypermethylation of Chronic Gastritis, in Relation to Aging, Gender, Intestinal Metaplasia, and Chronic Inflammation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

BSAP (Pax5)-importin alpha 1 (Rch1) interaction identifies a nuclear localization sequence

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Rare lymphoid neoplasms coexpressing B- and T-cell antigens. The role of PAX-5 gene methylation in their pathogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Frequent CpG island methylation in precursor lesions and early gastric adenocarcinomas.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

MIM, a potential metastasis suppressor gene in bladder cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Paired box gene 5 is a novel tumor suppressor in hepatocellular carcinoma through interaction with p53 signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Analysis of prognostic factors in patients with nonmetastatic rhabdomyosarcoma treated on intergroup rhabdomyosarcoma studies III and IV: the Children's Oncology Group

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Pax-5 immunoexpression in various types of benign and malignant tumours: a high-throughput tissue microarray analysis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

A novel form of Epstein-Barr virus latency in normal B cells in vivo

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Downregulation of missing in metastasis gene (MIM) is associated with the progression of bladder transitional carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Heme oxygenase-1 protects against steatohepatitis in both cultured hepatocytes and mice

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

21 January 2018

Profile of aberrant CpG island methylation along multistep gastric carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

31 March 2020

Loss of p53 function through PAX-mediated transcriptional repression.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

31 March 2020

Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.511

31 March 2020

Identifiers

10.1038/ONC.2011.511

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22105368%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22105368%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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