(Q39440982)

12 September 2017

title

C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes (English)

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12 September 2017

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Makoto Hirata

1

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12 September 2017

Fumitaka Kugimiya

2

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12 September 2017

Atsushi Fukai

3

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12 September 2017

Taku Saito

4

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12 September 2017

Fumiko Yano

5

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12 September 2017

Toshiyuki Ikeda

6

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12 September 2017

Akihiko Mabuchi

7

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12 September 2017

Bishwa Raj Sapkota

8

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12 September 2017

Toru Akune

9

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12 September 2017

Nao Nishida

10

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12 September 2017

Noriko Yoshimura

11

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12 September 2017

Takumi Nakagawa

12

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12 September 2017

Katsushi Tokunaga

13

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12 September 2017

Kozo Nakamura

14

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12 September 2017

Ung-il Chung

15

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12 September 2017

Hiroshi Kawaguchi

16

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12 September 2017

publication date

17 November 2011

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12 September 2017

published in

Human Molecular Genetics

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12 September 2017

volume

21

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12 September 2017

issue

5

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12 September 2017

page(s)

1111-1123

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Developmental regulation of the growth plate

12 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Reaching a genetic and molecular understanding of skeletal development

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

CCAAT/enhancer-binding protein beta promotes osteoblast differentiation by enhancing Runx2 activity with ATF4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes

21 January 2018

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Osteoarthritis cartilage histopathology: grading and staging.

21 January 2018

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The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse.

21 January 2018

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Cohort profile: research on Osteoarthritis/Osteoporosis Against Disability study

21 January 2018

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The role of C/EBP genes in adipocyte differentiation.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

CCAAT/enhancer-binding protein homologous protein (CHOP) regulates osteoblast differentiation

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

How proteases regulate bone morphogenesis

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Altered endochondral bone development in matrix metalloproteinase 13-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Maturational disturbance of chondrocytes in Cbfa1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Overexpression of Runx2 directed by the matrix metalloproteinase-13 promoter containing the AP-1 and Runx/RD/Cbfa sites alters bone remodeling in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

CCAAT/enhancer binding protein beta mediates expression of matrix metalloproteinase 13 in human articular chondrocytes in inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

New experimental approaches in retrovirus-mediated expression screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Validity of histopathological grading of articular cartilage from osteoarthritic knee joints

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Radiological assessment of osteo-arthrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

Carminerin contributes to chondrocyte calcification during endochondral ossification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR540

21 January 2018

Identifiers

DOI

10.1093/HMG/DDR540

1 reference

12 September 2017

1 reference