(Q39445052)

12 September 2017

title

Construction and humanization of a functional bispecific EGFR × CD16 diabody using a refolding system (English)

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12 September 2017

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Ryutaro Asano

1

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12 September 2017

Makoto Nakayama

2

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12 September 2017

Hiroko Kawaguchi

3

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12 September 2017

Tsuguo Kubota

4

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12 September 2017

Takeshi Nakanishi

5

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12 September 2017

Mitsuo Umetsu

6

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12 September 2017

Hiroki Hayashi

7

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12 September 2017

Yu Katayose

8

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12 September 2017

Michiaki Unno

9

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12 September 2017

Toshio Kudo

10

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12 September 2017

Izumi Kumagai

11

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12 September 2017

language of work or name

English

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publication date

6 December 2011

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12 September 2017

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12 September 2017

volume

279

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12 September 2017

issue

2

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12 September 2017

page(s)

223-233

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Bispecific antibody conjugates in therapeutics

12 September 2017

cites work

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

A revival of bispecific antibodies

21 January 2018

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Bispecific and bifunctional single chain recombinant antibodies

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Crystal structure of a diabody, a bivalent antibody fragment

21 January 2018

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Efficient inhibition of multidrug-resistant human tumors with a recombinant bispecific anti-P-glycoprotein x anti-CD3 diabody.

21 January 2018

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Synergistic antitumor effect of bispecific CD19 x CD3 and CD19 x CD16 diabodies in a preclinical model of non-Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Efficient construction of a diabody using a refolding system: anti-carcinoembryonic antigen recombinant antibody fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Humanization of the bispecific epidermal growth factor receptor x CD3 diabody and its efficacy as a potential clinical reagent

21 January 2018

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Preferential heterodimerization of a bispecific diabody based on a humanized anti-EGFR antibody 528.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

An improved model of association for VH-VL immunoglobulin domains: asymmetries between VH and VL in the packing of some interface residues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Targeting of T lymphocytes against EGF-receptor+ tumor cells by bispecific monoclonal antibodies: requirement of CD3 molecule cross-linking for T-cell activation

21 January 2018

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Role of target antigen in bispecific-antibody-mediated killing of human glioblastoma cells: a pre-clinical study.

21 January 2018

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Immunomodulatory therapy of cancer with T cell-engaging BiTE antibody blinatumomab

21 January 2018

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Replacing the complementarity-determining regions in a human antibody with those from a mouse

21 January 2018

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Reshaping human antibodies for therapy

21 January 2018

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A humanized antibody that binds to the interleukin 2 receptor

21 January 2018

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Humanized antibodies for antiviral therapy

21 January 2018

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Humanization of mouse ONS-M21 antibody with the aid of hybrid variable regions.

21 January 2018

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Critical contribution of VH-VL interaction to reshaping of an antibody: The case of humanization of anti-lysozyme antibody, HyHEL-10

21 January 2018

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The effect of variable domain orientation and arrangement on the antigen-binding activity of a recombinant human bispecific diabody

21 January 2018

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A novel CD19-directed recombinant bispecific antibody derivative with enhanced immune effector functions for human leukemic cells.

21 January 2018

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Effective elimination of acute myeloid leukemic cells by recombinant bispecific antibody derivatives directed against CD33 and CD16.

21 January 2018

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A recombinant bispecific single-chain Fv antibody against HLA class II and FcgammaRIII (CD16) triggers effective lysis of lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Application of the Fc fusion format to generate tag-free bi-specific diabodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Diabody-based recombinant formats of humanized IgG-like bispecific antibody with effective retargeting of lymphocytes to tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Highly enhanced cytotoxicity of a dimeric bispecific diabody, the hEx3 tetrabody

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Immunoglobulin VH gene expression in human aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Structural aspects of human IgM antibodies expressed in chronic B lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

The role of hydrogen bonding via interfacial water molecules in antigen-antibody complexation. The HyHEL-10-HEL interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Human Fcgamma receptor IIb expressed in Escherichia coli reveals IgG binding capability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

Cytotoxic enhancement of a bispecific diabody by format conversion to tandem single-chain variable fragment (taFv): the case of the hEx3 diabody

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08417.X

10.1111/J.1742-4658.2011.08417.X

21 January 2018

Identifiers

DOI

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12 September 2017

1 reference