(Q39447519)

12 September 2017

title

Synergistic antitumor activity of lapatinib and retinoids on a novel subtype of breast cancer with coamplification of ERBB2 and RARA. (English)

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Erb-b2 receptor tyrosine kinase 2

12 September 2017

main subject

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G Paroni

1

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12 September 2017

M Fratelli

2

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12 September 2017

G Gardini

3

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12 September 2017

C Bassano

4

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12 September 2017

M Flora

5

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12 September 2017

A Zanetti

6

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12 September 2017

V Guarnaccia

7

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12 September 2017

P Ubezio

8

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12 September 2017

F Centritto

9

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12 September 2017

M Terao

10

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12 September 2017

E Garattini

11

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12 September 2017

language of work or name

English

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publication date

7 November 2011

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12 September 2017

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12 September 2017

volume

31

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12 September 2017

issue

29

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12 September 2017

page(s)

3431-3443

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New strategies in HER2-overexpressing breast cancer: many combinations of targeted drugs available

12 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Induction of PDCD4 tumor suppressor gene expression by RAR agonists, antiestrogen and HER-2/neu antagonist in breast cancer cells. Evidence for a role in apoptosis

21 January 2018

1 reference

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An improved empirical bayes approach to estimating differential gene expression in microarray time-course data: BETR (Bayesian Estimation of Temporal Regulation).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Gene expression regulation by retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

A robust characterization of retinoic acid response elements based on a comparison of sites in three species

21 January 2018

1 reference

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Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity

21 January 2018

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Novel anticancer targets: revisiting ERBB2 and discovering ERBB3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

TGF-beta signaling in breast cancer

21 January 2018

1 reference

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Chemotherapeutic activity of silymarin combined with doxorubicin or paclitaxel in sensitive and multidrug-resistant colon cancer cells

21 January 2018

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All trans-retinoic acid acts synergistically with hydroxytamoxifen and transforming-growth factor beta to stimulate apoptosis in MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Retinoid-induced growth arrest of breast carcinoma cells involves co-activation of multiple growth-inhibitory genes

21 January 2018

1 reference

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Desmosomes: new perpetrators in tumour suppression

21 January 2018

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Molecular predictors of response to trastuzumab and lapatinib in breast cancer.

21 January 2018

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Retinoids as differentiating agents in oncology: a network of interactions with intracellular pathways as the basis for rational therapeutic combinations

21 January 2018

1 reference

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ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis

21 January 2018

1 reference

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Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARalpha and PML-RARalpha

21 January 2018

1 reference

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Effects of 1,25-dihydroxy vitamin D3 on all-trans retinoic acid sensitive and resistant acute promyelocytic leukemia cells

21 January 2018

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Endogenous tumor suppression mediated by PTEN involves survivin gene silencing.

21 January 2018

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Cloning and characterization of a novel retinoid-inducible gene 1(RIG1) deriving from human gastric cancer cells

21 January 2018

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Trastuzumab--mechanism of action and use in clinical practice

21 January 2018

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Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

21 January 2018

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Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations

21 January 2018

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Cytostatic and cytotoxic effects of topotecan decoded by a novel mathematical simulation approach

21 January 2018

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Trastuzumab as adjuvant systemic therapy for HER2-positive breast cancer

21 January 2018

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Invasion and metastasis of a mammary tumor involves TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Lapatinib and breast cancer: current indications and outlook for the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

TGFbeta and retinoic acid intersect in immune-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Terminal differentiation of human breast cancer through PPAR gamma

21 January 2018

1 reference

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Downregulation of HER2 by RIG1 involves the PI3K/Akt pathway in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Retinoids, Retinoic Acid Receptors, and Breast Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Measurement of caspase activity: from cell populations to individual cells.

21 January 2018

1 reference

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The rationale and potential of cancer chemoprevention with special emphasis on breast cancer

21 January 2018

1 reference

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Akt phosphorylates and suppresses the transactivation of retinoic acid receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase

21 January 2018

1 reference

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Estrogen-induced retinoic acid receptor alpha 1 gene expression: role of estrogen receptor-Sp1 complex

21 January 2018

1 reference

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Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Induction of miR-21 by retinoic acid in estrogen receptor-positive breast carcinoma cells: biological correlates and molecular targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

RIG1 suppresses Ras activation and induces cellular apoptosis at the Golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Induction of apoptosis by the retinoid inducible growth regulator RIG1 depends on the NC motif in HtTA cervical cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Synergistic effects of retinoic acid and tamoxifen on human breast cancer cells: proteomic characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Rb/E2F4 and Smad2/3 link survivin to TGF-beta-induced apoptosis and tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

A new fork for clinical application: targeting forkhead transcription factors in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Retinoid, retinoic acid receptor beta and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Transforming growth factors-beta are not good biomarkers of chemopreventive efficacy in a preclinical breast cancer model system.

21 January 2018

1 reference

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Targeting tyrosine kinases in cancer: the second wave

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Chemoprevention of breast cancer: the Italian experience.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Effects of synthetic retinoids and retinoic acid isomers on the expression of alkaline phosphatase in F9 teratocarcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

The basic biology of HER2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

Estrogen receptor-negative breast cancer cells transfected with the estrogen receptor exhibit increased RAR alpha gene expression and sensitivity to growth inhibition by retinoic acid

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.506

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.506

1 reference

Dimensions Publication ID

12 September 2017

1009589077

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1 reference