(Q39453997)

English

Long-term proliferation of functional human NK cells, with conversion of CD56(dim) NK cells to a CD56 (bright) phenotype, induced by carcinoma cells co-expressing 4-1BBL and IL-12.

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Europe PubMed Central

PubMed publication ID

12 September 2017

Long-term proliferation of functional human NK cells, with conversion of CD56(dim) NK cells to a CD56 (bright) phenotype, induced by carcinoma cells co-expressing 4-1BBL and IL-12. (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

author name string

Alexander C Dowell

1

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Kimberley A Oldham

2

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Rupesh I Bhatt

3

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Steven P Lee

4

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Peter F Searle

5

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

publication date

22 October 2011

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Europe PubMed Central

PubMed publication ID

12 September 2017

Cancer Immunology, Immunotherapy

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Europe PubMed Central

PubMed publication ID

12 September 2017

61

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Europe PubMed Central

PubMed publication ID

12 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

615-628

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

https://scigraph.springernature.com/pub.10.1007/s00262-011-1122-3

0 references

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Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells

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CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells.

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The biology of human natural killer-cell subsets

1 reference

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Gene and protein characteristics reflect functional diversity of CD56dim and CD56bright NK cells.

1 reference

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Functions of natural killer cells

1 reference

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CD56bright natural killer (NK) cells: an important NK cell subset.

1 reference

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CD56bright human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts

1 reference

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NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs

1 reference

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CD62L expression identifies a unique subset of polyfunctional CD56dim NK cells

1 reference

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CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset.

1 reference

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CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets

1 reference

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Molecular and biological characterization of human 4-1BB and its ligand

1 reference

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Co-stimulation with 4-1BB ligand allows extended T-cell proliferation, synergizes with CD80/CD86 and can reactivate anergic T cells

1 reference

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Rejection of disseminated metastases of colon carcinoma by synergism of IL-12 gene therapy and 4-1BB costimulation

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Immunomodulatory gene therapy with interleukin 12 and 4-1BB ligand: long- term remission of liver metastases in a mouse model

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NK and CD8+ T cell-mediated eradication of poorly immunogenic B16-F10 melanoma by the combined action of IL-12 gene therapy and 4-1BB costimulation

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Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL.

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Fc-dependent expression of CD137 on human NK cells: insights into "agonistic" effects of anti-CD137 monoclonal antibodies

1 reference

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Estimates of cancer incidence and mortality in Europe in 2008.

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Treatment of metastatic renal cell carcinoma

1 reference

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Metastatic renal cell carcinoma: many treatment options, one patient

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Discrimination of live and early apoptotic mononuclear cells by the fluorescent SYTO 16 vital dye.

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Natural killer cell accumulation in tumors is dependent on IFN-gamma and CXCR3 ligands

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Clinical significance of the NKG2D ligands, MICA/B and ULBP2 in ovarian cancer: high expression of ULBP2 is an indicator of poor prognosis

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Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution.

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4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1.

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Cytokine-induced memory-like natural killer cells

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Adaptive immune features of natural killer cells

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NK cells as effectors of acquired immune responses: effector CD4+ T cell-dependent activation of NK cells following vaccination

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Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

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Human gammadelta T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement

1 reference

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Expansion of highly cytotoxic human natural killer cells for cancer cell therapy

1 reference

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MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

1 reference

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21 January 2018

Identifiers

10.1007/S00262-011-1122-3

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

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