(Q39457285)

English

Lipopolysaccharide-induced activation of beta2-integrin function in macrophages requires Irak kinase activity, p38 mitogen- activated protein kinase, and the Rap1 GTPase

scientific article published on January 2001

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Lipopolysaccharide-induced activation of beta2-integrin function in macrophages requires Irak kinase activity, p38 mitogen- activated protein kinase, and the Rap1 GTPase (English)

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

lipopolysaccharide

0 references

author name string

A Schmidt

1

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

E Caron

2

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

A Hall

3

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

language of work or name

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publication date

1 January 2001

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Europe PubMed Central

PMC publication ID

12 September 2017

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

12 September 2017

21

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

2

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

438-448

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

1 reference

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12 September 2017

Ras and Rap1: two highly related small GTPases with distinct function

1 reference

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IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

1 reference

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Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase

1 reference

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Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion

1 reference

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Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

1 reference

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Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily

1 reference

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The molecular pathogenesis of endotoxic shock and organ failure

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Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

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1 reference

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Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB

1 reference

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Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice

1 reference

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The Toll-receptor family and control of innate immunity

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Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

1 reference

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

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MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

1 reference

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12 September 2017

LPS-binding proteins and receptors

1 reference

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12 September 2017

The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)

1 reference

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12 September 2017

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

1 reference

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12 September 2017

The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock

1 reference

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12 September 2017

Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22

1 reference

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12 September 2017

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1 reference

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12 September 2017

Leukocyte adhesion--structure and function of human leukocyte beta2-integrins and their cellular ligands

1 reference

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12 September 2017

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

1 reference

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12 September 2017

TRAF6 is a signal transducer for interleukin-1

1 reference

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

1 reference

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Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

1 reference

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12 September 2017

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

1 reference

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12 September 2017

IRAK: a kinase associated with the interleukin-1 receptor

1 reference

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

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CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide

1 reference

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Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin

1 reference

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14 September 2017

Bacterial Endotoxins and Host Immune Responses

1 reference

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14 September 2017

The GTPase Rap1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators

1 reference

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The role of p38 mitogen-activated protein kinase in IL-1 beta transcription

1 reference

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Modulation of tumor necrosis factor and interleukin-1-dependent NF-kappaB activity by mPLK/IRAK.

1 reference

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Effects of IL-1 receptor-associated kinase (IRAK) expression on IL-1 signaling are independent of its kinase activity

1 reference

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Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction

1 reference

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Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide

1 reference

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Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

1 reference

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25 September 2017

Endotoxin signal transduction in macrophages.

1 reference

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25 September 2017

Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms

1 reference

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25 September 2017

Molecular mechanisms of endotoxin activity

1 reference

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Outside-in signaling by lipopolysaccharide through a tailless integrin

1 reference

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Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal

1 reference

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Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.

1 reference

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Rapid Ca2+-mediated activation of Rap1 in human platelets

1 reference

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Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

1 reference

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IL-1 receptor-associated kinase modulates host responsiveness to endotoxin.

1 reference

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Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants

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Cellular activation mechanisms in septic shock

1 reference

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21 August 2018

pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo

1 reference

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Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins

1 reference

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21 August 2018

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-density lipoprotein activates the small GTPases Rap1 and Ral in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage activation in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pulmonary vascular sequestration of neutrophils in endotoxemia is initiated by an effect of endotoxin on the neutrophil in the rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD14-deficient mice are exquisitely insensitive to the effects of LPS

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD11/CD18 leukocyte integrins: new signaling receptors for bacterial endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of stress-activated mitogen-activated protein kinase (p38) in beta 2-integrin-dependent neutrophil adhesion and the adhesion-dependent oxidative burst

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SB202190, a selective inhibitor of p38 mitogen-activated protein kinase, is a powerful regulator of LPS-induced mRNAs in monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both Erk and p38 kinases are necessary for cytokine gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.21.2.438-448.2001

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

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