(Q39458532)

12 September 2017

title

The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formation (English)

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12 September 2017

main subject

neoplastic stem cells

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J T Buijs

1

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12 September 2017

G van der Horst

2

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12 September 2017

C van den Hoogen

3

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12 September 2017

H Cheung

4

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12 September 2017

B de Rooij

5

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12 September 2017

J Kroon

6

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12 September 2017

M Petersen

7

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12 September 2017

P G M van Overveld

8

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12 September 2017

R C M Pelger

9

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12 September 2017

G van der Pluijm

10

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12 September 2017

language of work or name

English

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publication date

26 September 2011

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12 September 2017

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12 September 2017

volume

31

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12 September 2017

issue

17

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12 September 2017

page(s)

2164-2174

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Prospective identification of tumorigenic breast cancer cells

12 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Finding cancer stem cells: are aldehyde dehydrogenases fit for purpose?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

TGF-beta and BMP7 interactions in tumour progression and bone metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Skeletal complications of malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Prospective identification of tumorigenic prostate cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Noggin is required for normal lobe patterning and ductal budding in the mouse prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.400

Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.400

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.400

BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Efficient expression of a heterodimer of bone morphogenetic protein subunits using a baculovirus expression system

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.400

The epithelial-to-mesenchymal transition and cancer stem cells: a coalition against cancer therapies

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.400

Heterodimeric bone morphogenetic proteins show enhanced activity in vitro and in vivo

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.400

21 January 2018

Cancer statistics, 2010

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https://api.crossref.org/works/10.1038%2FONC.2011.400

Imaging bone morphogenetic protein 7 induced cell cycle arrest in experimental gliomas.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.400

Combinatorial gene therapy with BMP2/7 enhances cranial bone regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.400

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Whole-body bioluminescent imaging of human uveal melanoma in a new mouse model of local tumor growth and metastasis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.400

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.400

Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Stem cells, cancer, and cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Identification and expansion of human colon-cancer-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Lack of noggin expression by cancer cells is a determinant of the osteoblast response in bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Molecular definition of breast tumor heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Identification of human brain tumour initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Bone morphogenetic protein signal transduction in bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Nuclear beta-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

BMP-2/6 heterodimer is more effective than BMP-2 or BMP-6 homodimers as inductor of differentiation of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Epithelial plasticity, cancer stem cells and bone metastasis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Cancer stem cells: an old idea--a paradigm shift

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Targeting cancer stem cells for more effective therapies: Taking out cancer's locomotive engine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Combinatorial gene therapy for bone regeneration: cooperative interactions between adenovirus vectors expressing bone morphogenetic proteins 2, 4, and 7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

Interference with the microenvironmental support impairs the de novo formation of bone metastases in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.400

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.400

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Dimensions Publication ID

12 September 2017

1018716706

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Fatcat ID

release_zyennksuifguja6tbne73nt4ke

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1 reference