(Q39459093)

12 September 2017

Clinical and therapeutic relevance of PIM1 kinase in gastric cancer (English)

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12 September 2017

11

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Richie Soong

9

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author name string

Benedict Yan

1

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12 September 2017

Ee Xuan Yau

2

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12 September 2017

Sanjay Samanta

3

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12 September 2017

Chee Wee Ong

4

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12 September 2017

Kol Jia Yong

5

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12 September 2017

Lai Kuan Ng

6

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12 September 2017

Bhaskar Bhattacharya

7

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12 September 2017

Kiat Hon Lim

8

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12 September 2017

Khay Guan Yeoh

10

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12 September 2017

Patrick Tan

12

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12 September 2017

Yulin Lam

13

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12 September 2017

Manuel Salto-Tellez

14

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12 September 2017

Singapore Gastric Cancer Consortium

15

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12 September 2017

13 October 2011

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12 September 2017

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12 September 2017

15

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12 September 2017

2

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12 September 2017

188-197

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https://scigraph.springernature.com/pub.10.1007/s10120-011-0097-2

12 September 2017

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cites work

Global cancer statistics, 2002

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Asia-Pacific consensus guidelines on gastric cancer prevention

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Gastric cancer: trastuzumab trial results spur search for other targets.

21 January 2018

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Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Overexpression of Pim-1 during progression of prostatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Docking study yields four novel inhibitors of the protooncogene Pim-1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Isoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Gene expression profile predicts patient survival of gastric cancer after surgical resection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Localization of the human pim oncogene (PIM) to a region of chromosome 6 involved in translocations in acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Identification of c-Src as a potential therapeutic target for gastric cancer and of MET activation as a cause of resistance to c-Src inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Pathology of gastric intestinal metaplasia: clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

The oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

A study of HER2 gene amplification and protein expression in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Pim-1 kinase stability is regulated by heat shock proteins and the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-011-0097-2

Overexpression of Pim-1 in head and neck squamous cell carcinomas.

21 January 2018

1 reference

12 December 2020

Gain of chromosome 6p is an infrequent cause of increased PIM1 expression in B-cell non-Hodgkin's lymphomas

1 reference

12 December 2020

The human PIM-1 gene product is a protein serine kinase

1 reference

12 December 2020

Prognostic impact of protein overexpression of the proto-oncogene PIM-1 in gastric cancer

1 reference

12 December 2020

Altered subcellular localization of c-Myc protein identifies aggressive B-cell lymphomas harboring a c-MYC translocation

1 reference

12 December 2020

Overexpression of the oncogenic kinase Pim-1 leads to genomic instability.

1 reference

12 December 2020

Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects.

1 reference

12 December 2020

10.1007/S10120-011-0097-2

Identifiers

DOI

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release_s4ypp5g2pjfqxe7eg5o47ekja4

12 September 2017

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1 reference