(Q39460871)

English

Tumor-specific isoform switch of the fibroblast growth factor receptor 2 underlies the mesenchymal and malignant phenotypes of clear cell renal cell carcinomas

scientific article published on 26 February 2013

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scholarly article

1 reference

Europe PubMed Central

12 September 2017

Tumor-specific isoform switch of the fibroblast growth factor receptor 2 underlies the mesenchymal and malignant phenotypes of clear cell renal cell carcinomas (English)

1 reference

Europe PubMed Central

12 September 2017

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author name string

Qi Zhao

1

1 reference

Europe PubMed Central

12 September 2017

Otavia L Caballero

2

1 reference

Europe PubMed Central

12 September 2017

Ian D Davis

3

1 reference

Europe PubMed Central

12 September 2017

Eric Jonasch

4

1 reference

Europe PubMed Central

12 September 2017

Pheroze Tamboli

5

1 reference

Europe PubMed Central

12 September 2017

W K Alfred Yung

6

1 reference

Europe PubMed Central

12 September 2017

John N Weinstein

7

1 reference

Europe PubMed Central

12 September 2017

Kenna Shaw for TCGA research network

8

1 reference

Europe PubMed Central

12 September 2017

Robert L Strausberg

9

1 reference

Europe PubMed Central

12 September 2017

Jun Yao

10

1 reference

Europe PubMed Central

12 September 2017

language of work or name

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publication date

26 February 2013

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Europe PubMed Central

12 September 2017

Clinical Cancer Research

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Europe PubMed Central

12 September 2017

19

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Europe PubMed Central

12 September 2017

2460-2472

1 reference

Europe PubMed Central

12 September 2017

9

1 reference

Europe PubMed Central

12 September 2017

describes a project that uses

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Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/3644028

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inferred from PubMed Central ID database lookup

Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25

1 reference

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Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2.

1 reference

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Frequent pathway mutations of splicing machinery in myelodysplasia

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An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype

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No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

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The basics of epithelial-mesenchymal transition

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ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing

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The FGF family: biology, pathophysiology and therapy

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12 September 2017

Cancer genomics and genetics of FGFR2 (Review).

1 reference

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12 September 2017

FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

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A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

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Genome-wide association study identifies novel breast cancer susceptibility loci

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Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes

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Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis

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Keratinocyte growth factor expression and activity in cancer: implications for use in patients with solid tumors

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A crucial role for fibroblast growth factor signaling in embryonic mammary gland development

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Growth inhibition by keratinocyte growth factor receptor of human salivary adenocarcinoma cells through induction of differentiation and apoptosis

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Fibroblast growth factors

1 reference

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Alternative splicing of fibroblast growth factor receptors in human prostate cancer

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Characterization of recombinant human fibroblast growth factor (FGF)-10 reveals functional similarities with keratinocyte growth factor (FGF-7)

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Inhibition of growth of malignant rat prostate tumor cells by restoration of fibroblast growth factor receptor 2

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Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning

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Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy

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https://pubmed.ncbi.nlm.nih.gov/23444225

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Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer

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https://pubmed.ncbi.nlm.nih.gov/23444225

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Clear cell papillary renal cell carcinoma: a distinct histopathologic and molecular genetic entity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23444225

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https://pubmed.ncbi.nlm.nih.gov/23444225

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Identifiers

10.1158/1078-0432.CCR-12-3708

1 reference

Europe PubMed Central

12 September 2017

1 reference

Europe PubMed Central

12 September 2017

1 reference

Europe PubMed Central

12 September 2017

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