(Q39471420)

English

Plasmodium falciparum clones resistant to (S)-9-(3-hydroxy-2-phosphonylmethoxy-propyl)adenine carry amino acid substitutions in DNA polymerase delta

scientific article published on February 2000

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Plasmodium falciparum clones resistant to (S)-9-(3-hydroxy-2-phosphonylmethoxy-propyl)adenine carry amino acid substitutions in DNA polymerase delta (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Plasmodium falciparum

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author name string

Smeijsters LJ

1

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Zijlstra NM

2

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Veenstra J

3

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Verstrepen BE

4

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Heuvel C

5

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Overdulve JP

6

1 reference

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12 September 2017

de Vries E

7

1 reference

Europe PubMed Central

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12 September 2017

publication date

1 February 2000

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12 September 2017

Molecular and Biochemical Parasitology

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Europe PubMed Central

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12 September 2017

106

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12 September 2017

1

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12 September 2017

175-180

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PubMed publication ID

12 September 2017

Inhibition of the growth of Plasmodium falciparum and Plasmodium berghei by the DNA polymerase inhibitor HPMPA.

1 reference

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The effect of (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl) adenine on nuclear and organellar DNA synthesis in erythrocytic schizogony in malaria.

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Mechanism of action of acyclic nucleoside phosphonates against herpes virus replication.

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Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation

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Inhibition of herpes simplex virus DNA polymerase by diphosphates of acyclic phosphonylmethoxyalkyl nucleotide analogues

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K65R mutation of human immunodeficiency virus type 1 reverse transcriptase encodes cross-resistance to 9-(2-phosphonylmethoxyethyl)adenine

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Acyclic nucleotide analogues: synthesis, antiviral activity and inhibitory effects on some cellular and virus-encoded enzymes in vitro

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Intracellular metabolism and action of acyclic nucleoside phosphonates on DNA replication.

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Eukaryotic DNA polymerases

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A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives

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Amino acid changes coded by bacteriophage T4 DNA polymerase mutator mutants. Relating structure to function

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Functional consequences and exonuclease kinetic parameters of point mutations in bacteriophage T4 DNA polymerase

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Metabolic pathways for activation of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine in human lymphoid cells

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Biochemical basis for increased susceptibility to Cidofovir of herpes simplex viruses with altered or deficient thymidine kinase activity

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Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69

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Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions

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Inhibition of the 3' --> 5' exonuclease of human DNA polymerase epsilon by fludarabine-terminated DNA

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An improved technique for the cultivation of Plasmodium falciparum in vitro without daily medium change

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Simple, fast, and accurate fluorometric method to determine drug susceptibility of Plasmodium falciparum in 24-well suspension cultures.

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Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture

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DNA polymerase δ: gene sequences fromPlasmodium falciparumindicate that this enzyme is more highly conserved than DNA polymerase α

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The gene encoding DNA polymerase alpha from Plasmodium falciparum

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Identifiers

10.1016/S0166-6851(99)00202-9

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

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