(Q39472670)

12 September 2017

A nine-codon deletion mutation in the cytomegalovirus UL97 phosphotransferase gene confers resistance to ganciclovir (English)

1 reference

12 September 2017

0 references

S Chou

1

1 reference

12 September 2017

C L Meichsner

series ordinal

2

1 reference

12 September 2017

language of work or name

English

0 references

publication date

1 January 2000

1 reference

Antimicrobial Agents and Chemotherapy

12 September 2017

1 reference

12 September 2017

44

1 reference

12 September 2017

1

1 reference

12 September 2017

183-185

1 reference

Antiviral drug resistance in human cytomegalovirus

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

A recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

The Cys607-->Tyr change in the UL97 phosphotransferase confers ganciclovir resistance to two human cytomegalovirus strains recovered from two immunocompromised patients

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

The UL97 gene product of human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

Defined large-scale alterations of the human cytomegalovirus genome constructed by cotransfection of overlapping cosmids

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

Novel mutation in the CMV UL97 gene associated with resistance to ganciclovir therapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

Antiviral susceptibility testing of cytomegalovirus: criteria for detecting resistance to antivirals.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89650

Antiviral susceptibilities and analysis of UL97 and DNA polymerase sequences of clinical cytomegalovirus isolates from immunocompromised patients

4 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10602745

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Frequency of UL97 phosphotransferase mutations related to ganciclovir resistance in clinical cytomegalovirus isolates

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10602745

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.44.1.183-185.2000

1 reference

release_3jihyhqrqvdydjjjmtszx4fg4a

12 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3jihyhqrqvdydjjjmtszx4fg4a

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

12 September 2017

PubMed publication ID

10602745

1 reference