(Q39475200)

English

Comparative pharmacodynamic analysis of Q-T interval prolongation induced by the macrolides clarithromycin, roxithromycin, and azithromycin in rats

scientific article published on October 2000

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Comparative pharmacodynamic analysis of Q-T interval prolongation induced by the macrolides clarithromycin, roxithromycin, and azithromycin in rats (English)

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

0 references

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

author name string

H Ohtani

1

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

C Taninaka

2

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

E Hanada

3

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

H Kotaki

4

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

H Sato

5

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Y Sawada

6

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

T Iga

7

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

language of work or name

0 references

publication date

1 October 2000

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

44

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

10

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

2630-2637

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

12 September 2017

Clinical pharmacokinetic properties of the macrolide antibiotics. Effects of age and various pathophysiological states (Part I).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

12 September 2017

Association of intravenous erythromycin and potentially fatal ventricular tachycardia with Q-T prolongation (torsades de pointes).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

12 September 2017

QT-interval prolonging drugs: mechanisms and clinical relevance of their arrhythmogenic hazards

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

12 September 2017

Pharmacokinetic drug interactions of macrolides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

12 September 2017

Steady-state pharmacokinetics and electrocardiographic pharmacodynamics of clarithromycin and loratadine after individual or concomitant administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

14 September 2017

Myocardial potassium channels: electrophysiological and molecular diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

25 September 2017

The influence of cisapride and clarithromycin on QT intervals in healthy volunteers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

17 June 2018

QT prolongation and Torsades de Pointes associated with clarithromycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

17 June 2018

A review of erythromycin-induced malignant tachyarrhythmia--torsade de pointes. A case report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

17 June 2018

A comparative pharmacokinetic-pharmacodynamic study of the electrocardiographic effects of epinastine and terfenadine in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

17 June 2018

Erythromycin blocks the rapid component of the delayed rectifier potassium current and lengthens repolarization of guinea pig ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

17 June 2018

A pharmacokinetic analysis program (multi) for microcomputer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

17 June 2018

Evaluation of two assumptions: single straight line, and single normal distribution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

17 June 2018

Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

17 June 2018

Cardiac actions of erythromycin: influence of female sex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

21 August 2018

The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

21 August 2018

Single-channel activity of the Ca2+-dependent K+ channel is modulated by FK506 and rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

21 August 2018

QT interval prolongation and cardiac arrest during antibiotic therapy with spiramycin in a newborn infant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

21 August 2018

Drug-induced torsades de pointes: a possible interaction of terfenadine and erythromycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

21 August 2018

Relationship between QaT and RR intervals in rats, guinea pigs, rabbits, and primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90127

21 August 2018

Determination of erythromycin, clarithromycin, roxithromycin, and azithromycin in plasma by high-performance liquid chromatography with amperometric detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/10991836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrent ventricular tachycardia associated with QT prolongation after mitral valve replacement and its association with intravenous administration of erythromycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10991836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10991836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A viewpoint on drugs that prolong the QTc interval

1 reference

https://pubmed.ncbi.nlm.nih.gov/10991836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic-pharmacodynamic analysis of the electrocardiographic effects of terfenadine and quinidine in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10991836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of roxithromycin, erythromycin and troleandomycin on their N-demethylation by rat and human cytochrome P450 enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10991836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and Ionic Mechanisms Underlying Erythromycin-Induced Long QT Intervals and Torsade de Pointes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10991836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic analysis of the electrocardiographic interaction between disopyramide and erythromycin in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10991836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic-pharmacodynamic analysis of the arrhythmogenic potency of a novel antiallergic agent, ebastine, in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10991836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.44.10.2630-2637.2000

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

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