(Q39475894)

English

Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy

scientific article published on January 2001

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scholarly article

1 reference

Europe PubMed Central

12 September 2017

Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy (English)

1 reference

Europe PubMed Central

12 September 2017

Pseudomonas aeruginosa

0 references

multiple drug resistance

1 reference

based on heuristic

inferred from title

author name string

O Lomovskaya

1

1 reference

Europe PubMed Central

12 September 2017

M S Warren

2

1 reference

Europe PubMed Central

12 September 2017

A Lee

3

1 reference

Europe PubMed Central

12 September 2017

J Galazzo

4

1 reference

Europe PubMed Central

12 September 2017

R Fronko

5

1 reference

Europe PubMed Central

12 September 2017

M Lee

6

1 reference

Europe PubMed Central

12 September 2017

J Blais

7

1 reference

Europe PubMed Central

12 September 2017

D Cho

8

1 reference

Europe PubMed Central

12 September 2017

S Chamberland

9

1 reference

Europe PubMed Central

12 September 2017

T Renau

10

1 reference

Europe PubMed Central

12 September 2017

R Leger

11

1 reference

Europe PubMed Central

12 September 2017

S Hecker

12

1 reference

Europe PubMed Central

12 September 2017

W Watkins

13

1 reference

Europe PubMed Central

12 September 2017

K Hoshino

14

1 reference

Europe PubMed Central

12 September 2017

H Ishida

15

1 reference

Europe PubMed Central

12 September 2017

V J Lee

16

1 reference

Europe PubMed Central

12 September 2017

language of work or name

0 references

publication date

1 January 2001

1 reference

Europe PubMed Central

12 September 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

12 September 2017

45

1 reference

Europe PubMed Central

12 September 2017

105-116

1 reference

Europe PubMed Central

12 September 2017

1

1 reference

Europe PubMed Central

12 September 2017

Ineffectiveness of topoisomerase mutations in mediating clinically significant fluoroquinolone resistance in Escherichia coli in the absence of the AcrAB efflux pump

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Characterization of a Pseudomonas aeruginosa efflux pump contributing to aminoglycoside impermeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Involvement of an active efflux system in the natural resistance of Pseudomonas aeruginosa to aminoglycosides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

The secondary multidrug transporter LmrP contains multiple drug interaction sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Multiple novel inhibitors of the NorA multidrug transporter of Staphylococcus aureus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Reversal of tetracycline resistance mediated by different bacterial tetracycline resistance determinants by an inhibitor of the Tet(B) antiport protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Bypassing the periplasm: reconstitution of the AcrAB multidrug efflux pump of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Use of a genetic approach to evaluate the consequences of inhibition of efflux pumps in Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Resistance to beta-lactam antibiotics in Pseudomonas aeruginosa due to interplay between the MexAB-OprM efflux pump and beta-lactamase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Inhibition of the emergence of ciprofloxacin resistance in Streptococcus pneumoniae by the multidrug efflux inhibitor reserpine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Multiple antibiotic resistance and efflux

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Interplay between chromosomal beta-lactamase and the MexAB-OprM efflux system in intrinsic resistance to beta-lactams in Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Characterization of the MexC-MexD-OprJ multidrug efflux system in DeltamexA-mexB-oprM mutants of Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Use of steroids to monitor alterations in the outer membrane of Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Overexpression of the mexC-mexD-oprJ efflux operon in nfxB-type multidrug-resistant strains of Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of gram-negative bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to beta-lactam resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Molecular basis of bacterial outer membrane permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Agents that increase the permeability of the outer membrane.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

31P nuclear magnetic resonance studies of bioenergetics and glycolysis in anaerobic Escherichia coli cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

Interplay between efflux pumps may provide either additive or multiplicative effects on drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

12 September 2017

The acrAB homolog of Haemophilus influenzae codes for a functional multidrug efflux pump

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

14 September 2017

Mutations in the gyrA and parC genes in fluoroquinolone-resistant clinical isolates of Pseudomonas aeruginosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

14 September 2017

Mechanisms of high-level resistance to quinolones in urinary tract isolates of Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

14 September 2017

Role of outer membrane barrier in efflux-mediated tetracycline resistance of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

14 September 2017

nfxC-type quinolone resistance in a clinical isolate of Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

14 September 2017

Compounds which increase the permeability of the Pseudomonas aeruginosa outer membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

14 September 2017

Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

14 September 2017

Mechanisms of resistance to fluoroquinolones: state-of-the-art 1992-1994.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

25 September 2017

Quinolone mode of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

25 September 2017

Multidrug resistance pumps in bacteria: variations on a theme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

25 September 2017

Prevention of drug access to bacterial targets: permeability barriers and active efflux

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

25 September 2017

Function of the Outer Membrane of Escherichia coli as a Permeability Barrier to Beta-Lactam Antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

25 September 2017

Kinetics of the multidrug transporter (P-glycoprotein) and its reversal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

25 September 2017

Inhibitors of efflux pumps in Pseudomonas aeruginosa potentiate the activity of the fluoroquinolone antibacterial levofloxacin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

17 June 2018

AcrA is a highly asymmetric protein capable of spanning the periplasm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

17 June 2018

Antibiotic resistance caused by gram-negative multidrug efflux pumps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

17 June 2018

Molecular cloning and functional analysis of a novel macrolide-resistance determinant, mefA, from Streptococcus pyogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

17 June 2018

Inhibition of the multidrug transporter NorA prevents emergence of norfloxacin resistance in Staphylococcus aureus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

17 June 2018

Inhibition of the tetracycline efflux antiport protein by 13-thio-substituted 5-hydroxy-6-deoxytetracyclines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

17 June 2018

Bioenergetics of the staphylococcal multidrug export protein QacA. Identification of distinct binding sites for monovalent and divalent cations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

21 August 2018

The role of mex-gene products in antibiotic extrusion in Pseudomonas aeruginosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

21 August 2018

Mechanisms of resistance to beta-lactam antibiotics amongst Pseudomonas aeruginosa isolates collected in the UK in 1993.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90247

21 August 2018

Efflux pumps in bacteria: overview, clinical relevance, and potential pharmaceutical target

1 reference

https://pubmed.ncbi.nlm.nih.gov/11120952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of OprM-deficient mutants of Pseudomonas aeruginosa by transposon insertion mutagenesis: evidence of involvement in multiple antibiotic resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/11120952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of genes associated with antibiotic extrusion in Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/11120952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interplay between the efflux pump and the outer membrane permeability barrier in fluorescent dye accumulation in Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/11120952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of fluorescence probes to monitor function of the subunit proteins of the MexA-MexB-oprM drug extrusion machinery in Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/11120952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interplay between the MexA-MexB-OprM multidrug efflux system and the outer membrane barrier in the multiple antibiotic resistance of Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/11120952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.45.1.105-116.2001

1 reference

Europe PubMed Central

12 September 2017

1 reference

Europe PubMed Central

12 September 2017

1 reference

Europe PubMed Central

12 September 2017

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