(Q39482570)

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A synonymous polymorphism of the Tristetraprolin (TTP) gene, an AU-rich mRNA-binding protein, affects translation efficiency and response to Herceptin treatment in breast cancer patients.

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scholarly article

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Europe PubMed Central

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11 February 2020

A synonymous polymorphism of the Tristetraprolin (TTP) gene, an AU-rich mRNA-binding protein, affects translation efficiency and response to Herceptin treatment in breast cancer patients (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21875902%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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Christian Touriol

6

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11 February 2020

author name string

Paola Griseri

1

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11 February 2020

Christine Bourcier

2

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11 February 2020

Corinne Hieblot

3

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11 February 2020

Khadija Essafi-Benkhadir

4

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11 February 2020

Emmanuel Chamorey

5

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11 February 2020

Gilles Pagès

7

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11 February 2020

publication date

29 August 2011

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11 February 2020

Human Molecular Genetics

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11 February 2020

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11 February 2020

23

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11 February 2020

4556-4568

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11 February 2020

Modulation of mRNA stability as a novel therapeutic approach

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Immunological characterization of tristetraprolin as a low abundance, inducible, stable cytosolic protein

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Control of mRNA decay by phosphorylation of tristetraprolin.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Tristetraprolin binds to the 3'-untranslated region of cyclooxygenase-2 mRNA. A polyadenylation variant in a cancer cell line lacks the binding site

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Tristetraprolin regulates CXCL1 (KC) mRNA stability

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Tristetraprolin down-regulates interleukin-8 and vascular endothelial growth factor in malignant glioma cells.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Tristetraprolin regulates the stability of HIF-1alpha mRNA during prolonged hypoxia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Current perspective - trastuzumab

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Silent polymorphisms speak: how they affect pharmacogenomics and the treatment of cancer

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Stability of the LATS2 tumor suppressor gene is regulated by tristetraprolin

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

X chromosomal abnormalities in basal-like human breast cancer

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Genetic variations in ZFP36 and their possible relationship to autoimmune diseases

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Selective and mutational patterns associated with gene expression in humans: influences on synonymous composition and intron presence

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

A "silent" polymorphism in the MDR1 gene changes substrate specificity

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Alternative splicing: good and bad effects of translationally silent substitutions.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Silent mutations in sight: co-variations in tRNA abundance as a key to unravel consequences of silent mutations.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Synonymous mutations and ribosome stalling can lead to altered folding pathways and distinct minima

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Translation efficiency is determined by both codon bias and folding energy

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Analyzing real-time PCR data by the comparative C(T) method

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

An upstream open reading frame within an IRES controls expression of a specific VEGF-A isoform

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR390

21 January 2018

Identifiers

10.1093/HMG/DDR390

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21875902%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21875902%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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