(Q39487525)

12 September 2017

title

The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states (English)

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12 September 2017

Tim J Wigle

1

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12 September 2017

Sarah K Knutson

2

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12 September 2017

Lei Jin

3

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12 September 2017

Kevin W Kuntz

4

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12 September 2017

Roy M Pollock

5

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12 September 2017

Victoria M Richon

6

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12 September 2017

Robert A Copeland

7

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12 September 2017

Margaret Porter Scott

8

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12 September 2017

language of work or name

English

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publication date

17 August 2011

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12 September 2017

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12 September 2017

volume

585

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12 September 2017

issue

19

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12 September 2017

page(s)

3011-3014

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

12 September 2017

cites work

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

Role of hPHF1 in H3K27 methylation and Hox gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

Regulation of tumor angiogenesis by EZH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

SET7/9 Catalytic Mutants Reveal the Role of Active Site Water Molecules in Lysine Multiple Methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

Structural Biology of Human H3K9 Methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.08.018

10.1016/J.FEBSLET.2011.08.018

21 January 2018

Identifiers

DOI

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12 September 2017

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