(Q39492314)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21831009%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

The TGF-β superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism (English)

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10 February 2020

0 references

3

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10 February 2020

Mohammad G Mohammad

5

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10 February 2020

Christopher P. Marquis

8

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10 February 2020

John A. Hamilton

14

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10 February 2020

author name string

Samuel N Breit

1

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10 February 2020

Heiko Johnen

2

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10 February 2020

Vicky W W Tsai

4

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10 February 2020

Tamara Kuffner

6

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10 February 2020

Hong Ping Zhang

7

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10 February 2020

Lele Jiang

9

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10 February 2020

Glen Lockwood

10

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10 February 2020

Michelle Lee-Ng

11

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10 February 2020

Yasmin Husaini

12

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10 February 2020

Liyun Wu

13

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10 February 2020

David A Brown

15

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10 February 2020

publication date

11 August 2011

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10 February 2020

published in

Growth Factors Journal

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10 February 2020

volume

29

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10 February 2020

issue

5

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10 February 2020

page(s)

187-195

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Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1.

10 February 2020

cites work

1 reference

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Cyclooxygenase inhibitors induce the expression of the tumor suppressor gene EGR-1, which results in the up-regulation of NAG-1, an antitumorigenic protein

21 January 2018

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Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53.

21 January 2018

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The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcome

21 January 2018

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Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer

21 January 2018

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The propeptide of macrophage inhibitory cytokine (MIC-1), a TGF-beta superfamily member, acts as a quality control determinant for correctly folded MIC-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Expression of a novel member of the TGF-beta superfamily, growth/differentiation factor-15/macrophage-inhibiting cytokine-1 (GDF-15/MIC-1) in adult rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity

21 January 2018

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Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer

21 January 2018

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Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosis

21 January 2018

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Macrophage inhibitory cytokine-1 is increased in individuals before type 2 diabetes diagnosis but is not an independent predictor of type 2 diabetes: the Whitehall II study

21 January 2018

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Protein profiling of microdissected prostate tissue links growth differentiation factor 15 to prostate carcinogenesis

21 January 2018

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Differing roles for urokinase and tissue-type plasminogen activator in collagen-induced arthritis

21 January 2018

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Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Growth-differentiation factor-15 is a robust, independent predictor of 11-year mortality risk in community-dwelling older adults: the Rancho Bernardo Study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Analysis of differential gene expression in human melanocytic tumour lesions by custom made oligonucleotide arrays

21 January 2018

1 reference

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The K/BxN mouse: a model of human inflammatory arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Increased serum concentrations of macrophage inhibitory cytokine-1 in patients with obesity and type 2 diabetes mellitus: the influence of very low calorie diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Growth-differentiation factor-15 for early risk stratification in patients with acute chest pain

21 January 2018

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https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Gene expression in poorly differentiated papillary thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Macrophage Inhibitory Cytokine-1 H6D Polymorphism, Prostate Cancer Risk, and Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Induction of GDF-15/NAG-1/MIC-1 in human lung carcinoma cells by retinoid-related molecules and assessment of its role in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Profile of gene expression regulated by induced p53: connection to the TGF-beta family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Circulating concentrations of growth-differentiation factor 15 in apparently healthy elderly individuals and patients with chronic heart failure as assessed by a new immunoradiometric sandwich assay

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Growth-differentiation factor-15 for risk stratification in patients with stable and unstable coronary heart disease: results from the AtheroGene study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Growth differentiation factor-15: a new biomarker in cardiovascular disease

21 January 2018

1 reference

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Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers

21 January 2018

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Growth differentiation factor-15 for prognostic assessment of patients with acute pulmonary embolism.

21 January 2018

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Indole-3-carbinol and 3,3'-diindolylmethane induce expression of NAG-1 in a p53-independent manner

21 January 2018

1 reference

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NSAID-activated gene-1 as a molecular target for capsaicin-induced apoptosis through a novel molecular mechanism involving GSK3beta, C/EBPbeta and ATF3.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Placental transforming growth factor-beta is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Growth-differentiation factor-15 is an independent marker of cardiovascular dysfunction and disease in the elderly: results from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) Study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

H6D polymorphism in macrophage-inhibitory cytokine-1 gene associated with prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Aminothiol WR1065 induces differential gene expression in the presence of wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Substantial genetic influence on cognitive abilities in twins 80 or more years old.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Quantitative analysis of macrophage inhibitory cytokine-1 (MIC-1) gene expression in human prostatic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Growth differentiation factor-15 in idiopathic pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

A p53-type response element in the GDF15 promoter confers high specificity for p53 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3beta/NAG-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Aberrant Neuropeptide Y and Macrophage Inhibitory Cytokine-1 Expression Are Early Events in Prostate Cancer Development and Are Associated with Poor Prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Expression of growth differentiation factor-15/ macrophage inhibitory cytokine-1 (GDF-15/MIC-1) in the perinatal, adult, and injured rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Serum macrophage inhibitory cytokine-1 concentrations correlate with the presence of prostate cancer bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Protein kinase C-dependent regulation of NAG-1/placental bone morphogenic protein/MIC-1 expression in LNCaP prostate carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Prodigiosin induces the proapoptotic gene NAG-1 via glycogen synthase kinase-3beta activity in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Three new serum markers for prostate cancer detection within a percent free PSA-based artificial neural network

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Expression and putative functions of GDF-15, a member of the TGF-beta superfamily, in human glioma and glioblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Elevated growth differentiation factor 15 expression in patients with congenital dyserythropoietic anemia type I.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Expression of growth differentiation factor 15 is not elevated in individuals with iron deficiency secondary to volunteer blood donation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Expression of macrophage inhibitory cytokine-1 in prostate cancer bone metastases induces osteoclast activation and weight loss

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Growth Differentiation Factor 15 for Risk Stratification and Selection of an Invasive Treatment Strategy in Non ST-Elevation Acute Coronary Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Loss of GDF-15 abolishes sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

Genetic Classification of Benign and Malignant Thyroid Follicular Neoplasia Based on a Three-Gene Combination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.607137

10.3109/08977194.2011.607137

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21831009%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference