(Q39493102)

12 September 2017

title

Gold(I) complexes of water-soluble diphos-type ligands: synthesis, anticancer activity, apoptosis and thioredoxin reductase inhibition (English)

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12 September 2017

Corinna Wetzel

1

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12 September 2017

Peter C Kunz

2

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12 September 2017

Matthias U Kassack

3

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12 September 2017

Alexandra Hamacher

4

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12 September 2017

Philip Böhler

5

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12 September 2017

Wim Watjen

6

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12 September 2017

Ingo Ott

7

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12 September 2017

Riccardo Rubbiani

8

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12 September 2017

Bernhard Spingler

9

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12 September 2017

language of work or name

English

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publication date

9 August 2011

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12 September 2017

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12 September 2017

volume

40

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12 September 2017

issue

36

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12 September 2017

page(s)

9212-9220

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Oxaliplatin, tetraplatin, cisplatin, and carboplatin: spectrum of activity in drug-resistant cell lines and in the cell lines of the National Cancer Institute's Anticancer Drug Screen panel

12 September 2017

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2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex

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Approaches for targeting mitochondria in cancer therapy

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Mitochondria are primary targets in apoptosis induced by the mixed phosphine gold species chlorotriphenylphosphine-1,3-bis(diphenylphosphino)propanegold(I) in melanoma cell lines

21 January 2018

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Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase

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Anti-tumor activity, in vitro and in vivo, of some triphenylphosphinegold(i) thionucleobases

21 January 2018

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In vitro antitumour activity of some triorganophosphinegold(i) thionucleobases

21 January 2018

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Anticancer gold(I)-phosphine complexes as potent autophagy-inducing agents

21 January 2018

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Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes

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Mitochondrial medicine: pharmacological targeting of mitochondria in disease

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Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells

21 January 2018

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In vivo and in vitro cardiotoxicity of a gold-containing antineoplastic drug candidate in the rabbit.

21 January 2018

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In vitro antitumor activity of the water soluble copper(I) complexes bearing the tris(hydroxymethyl)phosphine ligand.

21 January 2018

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Gold(I) chloride adducts of 1,3-bis(di-2-pyridylphosphino)propane: synthesis, structural studies and antitumour activity

21 January 2018

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Relationships between hydrophobicity, reactivity, accumulation and peripheral nerve toxicity of a series of platinum drugs

21 January 2018

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Role of lipophilicity in determining cellular uptake and antitumour activity of gold phosphine complexes

21 January 2018

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Auranofin disrupts selenium metabolism in Clostridium difficile by forming a stable Au-Se adduct.

21 January 2018

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Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands

21 January 2018

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21 January 2018

Thioredoxin reductase

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Gold(I) complex of N,N'-disubstituted cyclic thiourea with in vitro and in vivo anticancer properties-potent tight-binding inhibition of thioredoxin reductase

21 January 2018

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Targeting selenium metabolism and selenoproteins: novel avenues for drug discovery

21 January 2018

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Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols.

21 January 2018

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Imidazole-based phosphane gold(I) complexes as potential agents for cancer treatment: synthesis, structural studies and antitumour activity.

21 January 2018

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Apoptotic DNA fragmentation

21 January 2018

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A biochemical hallmark of apoptosis: internucleosomal degradation of the genome

21 January 2018

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Benzimidazol-2-ylidene gold(I) complexes are thioredoxin reductase inhibitors with multiple antitumor properties

21 January 2018

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A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: implications for anticancer therapeutics targeted to mitochondria.

21 January 2018

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21 January 2018

A short history of SHELX

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Comparison of the usefulness of the MTT, ATP, and calcein assays to predict the potency of cytotoxic agents in various human cancer cell lines.

21 January 2018

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SIR97: a new tool for crystal structure determination and refinement

21 January 2018

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Gold(III) Porphyrin 1a Induced Apoptosis by Mitochondrial Death Pathways Related to Reactive Oxygen Species

21 January 2018

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Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

21 January 2018

1 reference

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Single-crystal structure validation with the program PLATON

21 January 2018

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1107/S0021889802022112

9 April 2023

Identifiers

DOI

10.1039/C1DT10368G

1 reference

12 September 2017

1 reference