(Q39501245)

12 September 2017

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title

Cachectin and tumour necrosis factor as two sides of the same biological coin (English)

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12 September 2017

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Beutler B

1

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12 September 2017

Cerami A

series ordinal

2

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12 September 2017

language of work or name

English

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publication date

1 April 1986

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12 September 2017

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12 September 2017

320

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12 September 2017

584-588

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12 September 2017

6063

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https://scigraph.springernature.com/pub.10.1038/320584a0

12 September 2017

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cites work

Metabolic Response to Infection

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7 January 2021

Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever

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7 January 2021

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Nucleotide sequence of human monocyte interleukin 1 precursor cDNA

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Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

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7 January 2021

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

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7 January 2021

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity

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7 January 2021

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells

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7 January 2021

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

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7 January 2021

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

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Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

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Studies of endotoxin-induced decrease in lipoprotein lipase activity

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7 January 2021

Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells

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7 January 2021

Lipoprotein lipase suppression in 3T3-L1 cells by a haematoprotozoan-induced mediator from peritoneal exudate cells

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Weight loss associated with an endotoxin-induced mediator from peritoneal macrophages: the role of cachectin (tumor necrosis factor).

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An endotoxin-induced serum factor that causes necrosis of tumors

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Corynebacterium parvum as the Priming Agent in the Production of Tumor Necrosis Factor in the Mouse2

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7 January 2021

Tumour-necrosis factor from the rabbit. I. Mode of action, specificity and physicochemical properties

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Tumour-necrosis factor from the rabbit. II. Production by monocytes

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In vitro production of rabbit macrophage tumor cell cytotoxin.

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Role of first stimulating agents in the production of tumor necrosis factor

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Characterization of macrophage function in Mycobacterium lepraemurium-infected mice: sensitivity of mice to endotoxin and release of mediators and lysosomal enzymes after endotoxin treatment

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Macrophages from Babesia and malaria infected mice are primed for monokine release

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Macrophage-mediated cytotoxicity: role of a soluble macrophage cytotoxic factor similar to lymphotoxin and tumor necrosis factor

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Effect of tumour necrosis factor on cultured human melanoma cells

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Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.

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Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor

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7 January 2021

Molecular cloning of the complementary DNA for human tumor necrosis factor.

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Hypertriglyceridemia associated with Trypanosoma brucei brucei infection in rabbits: role of defective triglyceride removal.

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Molecular cloning of mouse tumour necrosis factor cDNA and its eukaryotic expression

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7 January 2021

Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor

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7 January 2021

Purification of rabbit tumor necrosis factor.

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7 January 2021

Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells

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Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity

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7 January 2021

Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization

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7 January 2021

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts

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7 January 2021

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors.

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7 January 2021

Modulation of endothelial cell hemostatic properties by tumor necrosis factor

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7 January 2021

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor

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7 January 2021

Tumor necrosis factor enhances eosinophil toxicity to Schistosoma mansoni larvae

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7 January 2021

A macrophage factor inhibits adipocyte gene expression: an in vitro model of cachexia

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7 January 2021

Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon

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7 January 2021

Studies of insulin resistance in adipocytes induced by macrophage mediator

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Evolutionary Rate at the Molecular Level

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7 January 2021

Identifiers

DOI

10.1038/320584A0

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Dimensions Publication ID

12 September 2017

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