(Q39502730)

12 September 2017

title

Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi (English)

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12 September 2017

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Sergio Hernán Szajnman

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author name string

Szajnman SH

1

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12 September 2017

Bailey BN

2

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12 September 2017

Docampo R

3

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12 September 2017

Rodriguez JB

4

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12 September 2017

language of work or name

English

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publication date

1 March 2001

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Bioorganic & Medicinal Chemistry Letters

12 September 2017

published in

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12 September 2017

volume

11

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12 September 2017

issue

6

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12 September 2017

page(s)

789-792

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The mechanisms of Trypanosoma cruzi invasion of mammalian cells

12 September 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900057-9

7 January 2021

Biology of Trypanosoma cruzi

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American trypanosomiasis (Chagas' disease)--a tropical disease now in the United States

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7 January 2021

Risk factors for Trypanosoma cruzi infection in California blood donors

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7 January 2021

Specific antibodies to Trypanosoma cruzi among blood donors in Los Angeles, California

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The challenge of Chagas' disease chemotherapy: an update of drugs assayed against Trypanosoma cruzi

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7 January 2021

Present status of chemotheraphy and chemoprophylaxis of human trypanosomiasis in the Western Hemisphere

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7 January 2021

In situ compositional analysis of acidocalcisomes in Trypanosoma cruzi

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7 January 2021

Presence of a plant-like proton-pumping pyrophosphatase in acidocalcisomes of Trypanosoma cruzi

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900057-9

7 January 2021

Overview of bisphosphonates

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900057-9

7 January 2021

Mechanisms of action of bisphosphonates

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7 January 2021

The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth

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7 January 2021

Role of protein modification reactions in programming interactions between ras-related GTPases and cell membranes

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7 January 2021

Protein prenyltransferases

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7 January 2021

Ras farnesyltransferase: a new therapeutic target

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7 January 2021

Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates

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7 January 2021

Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway

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7 January 2021

Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase

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7 January 2021

The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase.

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7 January 2021

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

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7 January 2021

Nitrogen-containing bisphosphonates as carbocation transition state analogs for isoprenoid biosynthesis

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7 January 2021

Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation

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7 January 2021

Structure−Activity Relationship of New Growth Inhibitors ofTrypanosomacruzi

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7 January 2021

Design, synthesis, and biological evaluation of new growth inhibitors of Trypanosoma cruzi (epimastigotes).

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7 January 2021

A method to assess invasion and intracellular replication of Trypanosoma cruzi based on differential uracil incorporation.

1 reference

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7 January 2021

Endocytosis of gold-labeled proteins and LDL by Trypanosoma cruzi

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7 January 2021

Inhibition of growth of Dictyostelium discoideum amoebae by bisphosphonate drugs is dependent on cellular uptake

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900057-9

7 January 2021

10.1016/S0960-894X(01)00057-9

Identifiers

DOI

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12 September 2017

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