(Q39508042)

English

Exchange protein directly activated by cAMP 1 (Epac1) is expressed in human neutrophils and mediates cAMP-dependent activation of the monomeric GTPase Rap1.

scientific article published on 12 July 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Exchange protein directly activated by cAMP 1 (Epac1) is expressed in human neutrophils and mediates cAMP-dependent activation of the monomeric GTPase Rap1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

author name string

Madhuri Dash-Koney

1

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Ravi K Deevi

2

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Cheryl McFarlane

3

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Karim Dib

4

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

publication date

12 July 2011

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Journal of Leukocyte Biology

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

90

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

741-749

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Getting to the site of inflammation: the leukocyte adhesion cascade updated

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Modulation of PMN-endothelial cells interactions by cyclic nucleotides

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

GEFs and GAPs: critical elements in the control of small G proteins

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

The GTPase Rap1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

A chemoattractant-mediated Gi-coupled pathway activates adenylyl cyclase in human neutrophils

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

cAMP protects neutrophils against TNF-alpha-induced apoptosis by activation of cAMP-dependent protein kinase, independently of exchange protein directly activated by cAMP (Epac).

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Cyclic AMP regulation of neutrophil apoptosis occurs via a novel protein kinase A-independent signaling pathway.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Beta-adrenoceptor stimulation and neutrophil accumulation in mouse airways

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Role for cAMP-protein kinase A signalling in augmented neutrophil adhesion and chemotaxis in sickle cell disease

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Characterisation of degranulation and phagocytic capacity of a human neutrophilic cellular model, PLB-985 cells

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Differentiation of PLB-985 myeloid cells into mature neutrophils, shown by degranulation of terminally differentiated compartments in response to N-formyl peptide and priming of superoxide anion production by granulocyte-macrophage colony-stimulatin

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Epac: a new cAMP target and new avenues in cAMP research

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Identification and characterization of a widely expressed form of adenylyl cyclase

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Identification of the binding site for fibrinogen recognition peptide gamma 383-395 within the alpha(M)I-domain of integrin alpha(M)beta2.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Epac1-Rap1 signaling regulates monocyte adhesion and chemotaxis

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Epac activation converts cAMP from a proliferative into a differentiation signal in PC12 cells

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Elevation of cyclic AMP in Jurkat T-cells provokes distinct transcriptional responses through the protein kinase A (PKA) and exchange protein activated by cyclic AMP (EPAC) pathways

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Epac inhibits apoptosis of human leukocytes.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Beta2 integrins target Rap GTPases to the plasma membrane by means of degranulation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

The tail of integrins, talin, and kindlins

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0211108

21 January 2018

Identifiers

10.1189/JLB.0211108

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

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