(Q39510527)

12 September 2017

Kinase inhibition by deoxy analogues of the resorcylic lactone L-783277. (English)

1 reference

12 September 2017

Marc Liniger

1

1 reference

12 September 2017

Christian Neuhaus

2

1 reference

12 September 2017

Tatjana Hofmann

3

1 reference

12 September 2017

Luca Fransioli-Ignazio

4

1 reference

12 September 2017

Michel Jordi

5

1 reference

12 September 2017

Peter Drueckes

6

1 reference

12 September 2017

Jörg Trappe

7

1 reference

12 September 2017

Doriano Fabbro

8

1 reference

12 September 2017

Karl-Heinz Altmann

9

1 reference

12 September 2017

20 October 2010

1 reference

ACS Medicinal Chemistry Letters

12 September 2017

1 reference

12 September 2017

2

1 reference

12 September 2017

1

1 reference

12 September 2017

22-27

1 reference

Extended kinase profile and properties of the protein kinase inhibitor nilotinib

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Synthesis of a resorcylic acid lactone (RAL) library using fluorous-mixture synthesis and profile of its selectivity against a panel of kinases

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Factors underlying sensitivity of cancers to small-molecule kinase inhibitors

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Targeting cancer with small molecule kinase inhibitors

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Therapeutic protein kinase inhibitors

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Molecular modeling and crystal structure of ERK2-hypothemycin complexes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Targeting the mTOR signaling network in cancer.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Chemistry and biology of resorcylic acid lactones

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Role of a cysteine residue in the active site of ERK and the MAPKK family

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Targeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

PDGFRA activating mutations in gastrointestinal stromal tumors.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

E6201 [(3S,4R,5Z,8S,9S,11E)-14-(ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (M

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Semisynthesis and cytotoxicity of hypothemycin analogues

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Antitumor efficacy of hypothemycin, a new Ras-signaling inhibitor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Molecular editing of kinase-targeting resorcylic acid lactones (RAL): Fluoroenone RAL.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Conformational analyses and MO studies of f152A1 and its analogues as potent protein kinase inhibitors

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018056

Discovery of an in vitro and in vivo potent resorcylic lactone analog of LL-Z1640-2 as anti-inflammatory lead, II

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900250

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Resorcylic acid lactones: naturally occurring potent and selective inhibitors of MEK

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900250

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Discovery of a potent, metabolically stabilized resorcylic lactone as an anti-inflammatory lead

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900250

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML1001807

1 reference

12 September 2017

1 reference

12 September 2017

PubMed publication ID

24900250

1 reference