(Q39513605)

12 September 2017

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title

Clinical pharmacokinetics of doxorubicin (English)

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12 September 2017

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P A Speth

1

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12 September 2017

Q G van Hoesel

series ordinal

2

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12 September 2017

C Haanen

series ordinal

3

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12 September 2017

1 July 1988

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Clinical Pharmacokinetics

12 September 2017

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12 September 2017

15

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12 September 2017

1

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12 September 2017

15-31

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https://scigraph.springernature.com/pub.10.2165/00003088-198815010-00002

12 September 2017

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cites work

Clinical evaluation of long-term, continuous-infusion doxorubicin

1 reference

12 December 2020

Effect of anthracycline antibiotics on oxygen radical formation in rat heart

1 reference

12 December 2020

Distribution of adriamycin in cancer patients: tissue uptakes, plasma concentration after IV and hepatic IA administration

1 reference

12 December 2020

Cytofluorescence localization of adriamycin in the nervous system. I. Distribution of the drug in the central nervous system of normal adult mice after intravenous injection.

1 reference

12 December 2020

Reduced cardiotoxicity and nephrotoxicity with preservation of antitumor activity of doxorubicin entrapped in stable liposomes in the LOU/M Wsl rat

1 reference

12 December 2020

Age dependence of the early-phase pharmacokinetics of doxorubicin

1 reference

12 December 2020

Mechanism of the inhibition of calf thymus DNA polymerases alpha and beta by daunomycin and adriamycin

1 reference

12 December 2020

Serum and tissue concentrations of doxorubicin after IV administration of doxorubicin or doxorubicin-DNA complex to patients with gastrointestinal cancer

1 reference

12 December 2020

Therapeutic drug monitoring in oncology. Problems and potential in antineoplastic therapy

1 reference

12 December 2020

Adriamycin (NSC-123,127): a new antibiotic with antitumor activity

1 reference

12 December 2020

Reappraisal of some dosage adjustment guidelines

1 reference

12 December 2020

Doxorubicin and cisplatin excretion into human milk.

1 reference

12 December 2020

Risk factors for doxorubicin-induced congestive heart failure

1 reference

12 December 2020

Effect of verapamil on in vitro cytotoxicity of adriamycin and vinblastine in human tumor cells.

1 reference

12 December 2020

Pharmacokinetics of doxorubicin, (2"R)-4'-O-tetrahydropyranyl-adriamycin and aclarubicin

1 reference

12 December 2020

Phase I and pharmacological studies of adriamycin administered intraperitoneally to patients with ovarian cancer

1 reference

12 December 2020

Digitalization in cytostatic therapy

1 reference

12 December 2020

Cellular and plasma adriamycin concentrations in long-term infusion therapy of leukemia patients

1 reference

12 December 2020

Toxicology of daunorubicin in animals and man.

1 reference

12 December 2020

The anthracycline antineoplastic drugs

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12 December 2020

Distribution and excretion of adriamycin in man.

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12 December 2020

Doxorubicin in pregnancy: possible transplacental passage

1 reference

12 December 2020

Acute doxorubicin toxicity. Relationship to pretreatment liver function, response, and pharmacokinetics in patients with acute nonlymphocytic leukemia

1 reference

12 December 2020

Non interference by heparin with the cytostatic effect of adriamycin: an in vitro study on a human promyelocytic leukaemia cell line

1 reference

12 December 2020

Pharmacologic studies of intra-hepatic artery chemotherapy with degradable starch microspheres.

1 reference

12 December 2020

Combined recombinant human interferon alpha 2 and cytotoxic agents studied in a clonogenic assay

1 reference

12 December 2020

The role of membranes in the mechanism of action of the antineoplastic agent adriamycin. Spin-labeling studies with chronically hypoxic and drug-resistant tumor cells.

1 reference

12 December 2020

Rapid distribution of adriamycin in the ascitic and pleural fluid of women with ovarian carcinomas

1 reference

12 December 2020

Etiology and treatment of chemotherapeutic agent extravasation injuries: a review

1 reference

12 December 2020

Studies on the in vivo disposition of adriamycin in human tumours which exhibit different responses to the drug

1 reference

12 December 2020

Enzymatic activation and binding of adriamycin to nuclear DNA

1 reference

12 December 2020

Comparative pharmacokinetics of doxorubicin and epirubicin in patients with gastrointestinal cancer

1 reference

12 December 2020

In vivo modulation of glutathione by buthionine sulfoximine: effect on marrow response to melphalan

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12 December 2020

Evidence of possible dose-dependent doxorubicin plasma kinetics in man

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12 December 2020

Pharmacokinetics of anticancer drugs in children

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12 December 2020

Influence of polysorbate 80 (Tween 80) and etoposide (VP-16-213) on the pharmacokinetics and urinary excretion of adriamycin and its metabolites in cancer patients

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12 December 2020

Plasma pharmacokinetics of adriamycin and adriamycinol: implications for the design of in vitro experiments and treatment protocols.

1 reference

12 December 2020

Anthracycline antitumour agents. A review of physicochemical, analytical and stability properties

1 reference

12 December 2020

Cellular and molecular effects of adriamycin on dividing and nondividing cells

1 reference

12 December 2020

Anthracycline cardiomyopathy monitored by morphologic changes

1 reference

12 December 2020

Intrahepatic and intravenous administration of adriamycin--a comparative pharmacokinetic study in patients with malignant liver tumours.

1 reference

12 December 2020

Adriamycin-induced changes in the surface membrane of sarcoma 180 ascites cells

1 reference

12 December 2020

Infusion-rate independent cellular adriamycin concentrations and cytotoxicity to human bone marrow clonogenic cells (CFU-GM).

1 reference

12 December 2020

Plasma pharmacokinetics of adriamycin after intrapleural administration

1 reference

12 December 2020

Clinical pharmacokinetics of adriamycin in hepatoma patients with cirrhosis

1 reference

12 December 2020

Plasma levels of doxorubicin after IV bolus injection and infusion of the doxorubicin-DNA complex in rabbits and man. Comparison with free doxorubicin

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12 December 2020

A Pharmacokinetic Evaluation of Free and DNA-Complexed Adriamycin: A Preliminary Study in Children with Malignant Disease

1 reference

12 December 2020

DAUNOMYCIN: A NEW ANTIBIOTIC WITH ANTITUMOR ACTIVITY

1 reference

12 December 2020

Stimulation of mouse heart and liver microsomal lipid peroxidation by anthracycline anticancer drugs: characterization and effects of reactive oxygen scavengers

1 reference

12 December 2020

Adriamycin metabolism in man. Evidence from urinary metabolites

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12 December 2020

[Drug interactions with anticancer agents]

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12 December 2020

A possible role for membrane lipid peroxidation in anthracycline nephrotoxicity

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12 December 2020

Cyclosporin A and its analogues as modifiers of adriamycin and vincristine resistance in a multi-drug resistant human lung cancer cell line

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12 December 2020

Concomitant adsorption and stability of some anthracycline antibiotics

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12 December 2020

Mitochondrial membrane modifications induced by adriamycin-mediated electron transport

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12 December 2020

Doxorubicin and 5-fluorouracil plasma concentrations and detectability in parotid saliva

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12 December 2020

Adriamycin in the treatment of relapsed primary malignant brain tumours.

1 reference

12 December 2020

Virologic and immunologic properties and response to daunomycin and adriamycin of a non-regressing mouse tumor derived from MSV-induced sarcoma

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12 December 2020

Comparative mammalian metabolism of adriamycin and daunorubicin

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12 December 2020

Drug level monitoring: cytostatics

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12 December 2020

Doxorubicin cytotoxicity to P388 lymphocytic leukemia as determined by alkaline elution and established assays

1 reference

12 December 2020

Quantitation of anthracyclines in human hematopoietic cell subpopulations by flow cytometry correlated with high pressure liquid chromatography

1 reference

12 December 2020

Hydroxyl radical production and DNA damage induced by anthracycline-iron complex

1 reference

12 December 2020

(2"-R)-4'-o-tetrahydropyranyladriamycin, a new anthracycline derivative; its effectiveness in lymphoid malignancies

1 reference

12 December 2020

Diffuse malignant mesothelioma of the pleura--intrapleural treatment with doxorubicin

1 reference

12 December 2020

In vivo cellular adriamycin concentrations related to growth inhibition of normal and leukemic human bone marrow cells

1 reference

12 December 2020

Relationship of adriamycin concentrations to the DNA lesions induced in hypoxic and euoxic L1210 cells

1 reference

12 December 2020

Adriamycin, 14-hydroxydaimomycin, a new antitumor antibiotic fromS. Peucetius var.caesius

1 reference

12 December 2020

Reversal of acquired resistance to vinca alkaloids and anthracycline antibiotics

1 reference

12 December 2020

Anticancer drug pharmacodynamics

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12 December 2020

Historic milestones in curative chemotherapy

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12 December 2020

Cellular pharmacodynamics of several anthracycline antibiotics

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12 December 2020

A phase I-II study of intensive-dose adriamycin for advanced breast cancer

1 reference

12 December 2020

Adriamycin cardiotoxicity: a survey of 1273 patients

1 reference

12 December 2020

Doxorubicin-induced congestive heart failure in adults

1 reference

12 December 2020

Pharmacokinetic study of i.v. infusions of adriamycin

1 reference

12 December 2020

Dose-response relationship in experimental and clinical oncology

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12 December 2020

In vitro release of biologically active adriamycin by magnetically responsive albumin microspheres

1 reference

12 December 2020

Effects of amphotericin B on adriamycin and melphalan cytotoxicity in human and murine ovarian carcinoma and in L1210 leukemia

1 reference

12 December 2020

An electron spin resonance study of the reduction of peroxides by anthracycline semiquinones

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12 December 2020

Time dependency of adriamycin and adriamycinol kinetics

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12 December 2020

Prediction of adriamycin disposition in cancer patients using a physiologic, pharmacokinetic model

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12 December 2020

Antitumor activity of new anthracycline analogues in combination with interferon alfa

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12 December 2020

Temperature dependence studies of adriamycin uptake and cytotoxicity.

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12 December 2020

The anticancer agent adriamycin can be actively cytotoxic without entering cells

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12 December 2020

Intravesical adriamycin instillations--what happens to the drug?

1 reference

12 December 2020

The effect of verapamil on the pharmacokinetics of adriamycin.

1 reference

12 December 2020

Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion

1 reference

12 December 2020

Plasma pharmacokinetics of adriamycin and its metabolites in humans with normal hepatic and renal function

1 reference

12 December 2020

Anthracycline analogs: the past, present, and future

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12 December 2020

Daunorubicin and adriamycin facilitate actinomycin D binding to poly(dA-dT)-poly(dA-dT)

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12 December 2020

Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies

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12 December 2020

Plasma and cellular adriamycin concentrations in patients with myeloma treated with ninety-six-hour continuous infusion

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12 December 2020

Body residue and metabolism of adriamycin and daunorubicin in control and phenobarbital-pretreated mice

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12 December 2020

Alterations in adriamycin efficacy by phenobarbital

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12 December 2020

Doxorubicin concentration time course in the myocardium after single administration to the dog. Possible role in the cardiac effects

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12 December 2020

1 reference

12 December 2020

Combination chemotherapy with adriamycin and streptozotocin; II. Clinicopharmacologic correlation of augmented adriamycin toxicity caused by streptozotocin

1 reference

12 December 2020

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

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12 December 2020

Membrane transport of anthracyclines

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12 December 2020

Doxorubicin (75 mg/m2) for hepatocellular carcinoma: clinical and pharmacokinetic results

1 reference

12 December 2020

Survival of hematopoietic and leukemic colony-forming cells in vivo following the administration of daunorubicin or adriamycin

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12 December 2020

Treatment of bladder cancer with intravesical instillation of adriamycin

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12 December 2020

Circadian timing of cancer chemotherapy

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12 December 2020

Recombinant leukocyte A interferon with doxorubicin. A phase I study in advanced solid neoplasms and implications for hepatocellular carcinoma

1 reference

12 December 2020

Cleavage of DNA by mammalian DNA topoisomerase II

1 reference

12 December 2020

Comparative pharmacokinetics of daunomycin and adriamycin in several animal species

1 reference

12 December 2020

Adriamycin chemotherapy--efficacy, safety, and pharmacologic basis of an intermittent single high-dosage schedule.

1 reference

12 December 2020

Carrier-mediated transport of daunorubicin, adriamycin, and rubidazone in ehrlich ascites tumour cells

1 reference

12 December 2020

The inhibition in vitro of DNA polymerase and RNA polymerases by daunomycin and adriamycin

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12 December 2020

[The pharmacokinetics of adriamycin and adriamycin-metabolites (author's transl)]

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12 December 2020

Genetic and biochemical characterization of multidrug resistance

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12 December 2020

Chemotherapy for acute leukemia during pregnancy. Five case reports

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12 December 2020

Cancer chemotherapy: past, present, and future--Part I

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12 December 2020

Treatment of chemotherapy extravasation: current status

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12 December 2020

Effects of amphotericin B with combination chemotherapy on response rates and on survival in non-small cell carcinoma of the lung

1 reference

12 December 2020

Positive interactions between human interferon and cyclophosphamide or adriamycin in a human tumor model system

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12 December 2020

Pharmacokinetics of anthracyclines in dogs: evidence for structure-related body distribution and reduction to their hydroxy metabolites

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12 December 2020

Non-invasive evaluation of anthracycline-induced cardiotoxicity in man.

1 reference

12 December 2020

Preliminary pharmacokinetic model for adriamycin (NSC-123127)

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12 December 2020

Acute leukemia in pregnancy: report of five cases treated with a combination which included a low dose of adriamycin

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12 December 2020

Aspects of cytotoxic drug penetration, with particular reference to anthracyclines

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12 December 2020

A comparison of the effects of daunomycin and adriamycin on various DNA polymerases

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12 December 2020

Comparison of the sensitivity of normal hematopoietic and transplanted lymphoma colony-forming cells to chemotherapeutic agents administered in vivo

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12 December 2020

10.2165/00003088-198815010-00002

Identifiers

DOI

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Dimensions Publication ID

12 September 2017

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