(Q39516918)

English

Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces beta(3)-adrenoceptor-mediated relaxation, causing rat detrusor overactivity

scientific article published on 25 February 2008

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scholarly article

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3 January 2020

Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces beta(3)-adrenoceptor-mediated relaxation, causing rat detrusor overactivity (English)

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3 January 2020

Marcelo N. Muscara

6

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3 January 2020

Gilberto de Nucci

9

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3 January 2020

Angelina Zanesco

10

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3 January 2020

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3 January 2020

author name string

F Z T Mónica

1

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3 January 2020

A A O Bricola

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3 January 2020

F R Báu

3

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3 January 2020

L L Lopes Freitas

4

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3 January 2020

S A Teixeira

5

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3 January 2020

F M F Abdalla

7

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3 January 2020

C S Porto

8

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3 January 2020

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25 February 2008

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3 January 2020

British Journal of Pharmacology

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3 January 2020

153

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3 January 2020

8

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3 January 2020

1659-1668

1 reference

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3 January 2020

Anticholinergic drugs in patients with bladder outlet obstruction and lower urinary tract symptoms: A systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Alpha1-, alpha2- and beta-adrenoceptors in the urinary bladder, urethra and prostate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Calcium events in smooth muscles and their interstitial cells; physiological roles of sparks

1 reference

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12 September 2017

Mechanisms of beta 3-adrenoceptor-induced eNOS activation in right atrial and left ventricular human myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Urinary bladder contraction and relaxation: physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Prevalence and burden of overactive bladder in the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Nitric oxide and the lower urinary tract: current concepts, future prospects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Muscarinic receptor subtypes and management of the overactive bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Nitric oxide and the proliferation of vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Beta 3-adrenoceptor stimulation induces vasorelaxation mediated essentially by endothelium-derived nitric oxide in rat thoracic aorta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Muscarinic receptor subtypes modulating smooth muscle contractility in the urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Species differences in the distribution of beta-adrenoceptor subtypes in bladder smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Muscarinic acetylcholine receptor subtypes mediating urinary bladder contractility and coupling to GTP binding proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Effects of inhibition of the L-arginine/nitric oxide pathway in the rat lower urinary tract in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

12 September 2017

Effects of gender, age and hypertension on beta-adrenergic receptor function in rat urinary bladder.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

15 June 2018

Chronic nitric oxide inhibition model six years on.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

15 June 2018

Activation of alpha 1-adrenoceptors increases [3H]inositol metabolism in rat vas deferens and caudal artery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

15 June 2018

Chronic inhibition of nitric oxide synthesis. A new model of arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

15 June 2018

Purification of insoluble nitric oxide synthase from rat cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

15 June 2018

Regional difference in functional roles of cAMP and cGMP in lower urinary tract smooth muscle contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

15 June 2018

Overactive bladder: prevalence and implications in Brazil.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

21 August 2018

Advantages for transdermal over oral oxybutynin to treat overactive bladder: Muscarinic receptor binding, plasma drug concentration, and salivary secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

21 August 2018

The M2 muscarinic receptor mediates contraction through indirect mechanisms in mouse urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

21 August 2018

Demonstration of bladder selective muscarinic receptor binding by intravesical oxybutynin to treat overactive bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

21 August 2018

Cystometric findings in mice lacking muscarinic M2 or M3 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

21 August 2018

Endothelial beta3-adrenoceptors mediate vasorelaxation of human coronary microarteries through nitric oxide and endothelium-dependent hyperpolarization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

21 August 2018

A quantitative analysis of mRNA expression of alpha 1 and beta-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

21 August 2018

Inducible nitric oxide synthase promotes pathophysiological consequences of experimental bladder outlet obstruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

21 August 2018

Upregulation of muscarinic receptors by long-term nitric oxide inhibition in the rat ileum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438257

21 August 2018

Activity and expression of nitric oxide synthase in the hypertrophied rat bladder and the effect of nitric oxide on bladder smooth muscle growth

1 reference

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21 August 2018

Different distribution of nitric oxide synthase and soluble guanylyl cyclase activities in the detrusor and proximal urethra of the rabbit

1 reference

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21 August 2018

Relationship of mass of obstructed rat bladders and responsiveness to adrenergic stimulation

1 reference

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21 August 2018

Beta-adrenoceptor agonists stimulate endothelial nitric oxide synthase in rat urinary bladder urothelial cells.

1 reference

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21 August 2018

Localization of constitutive nitric oxide synthase isoforms and the nitric oxide target enzyme soluble guanylyl cyclase in the human bladder

1 reference

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21 August 2018

Pharmacological characterization of beta-adrenoceptors mediating relaxation of the rat urinary bladder in vitro

1 reference

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21 August 2018

Human Idiopathic and Neurogenic Overactive Bladders and the Role of M2 Muscarinic Receptors in Contraction

1 reference

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12 December 2020

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Long-term nitric oxide inhibition and chronotropic responses in rat isolated right atria

1 reference

https://pubmed.ncbi.nlm.nih.gov/18297104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of estrogen on intracellular signaling pathways linked to activation of M(2)- and M(3)-muscarinic acetylcholine receptors in the rat myometrium

1 reference

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12 December 2020

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Escherichia coli-induced inducible nitric oxide synthase and cyclooxygenase expression in the mouse bladder and kidney

1 reference

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1 reference

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1 reference

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Physiological and morphometric studies into the pathophysiology of detrusor hyperreflexia in neuropathic patients

1 reference

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12 December 2020

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Co-existence of nitrergic, peptidergic and acetylcholine esterase-positive nerves in the pig lower urinary tract

1 reference

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12 December 2020

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Urinary bladder-urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase models idiopathic voiding disorders in humans

1 reference

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Identifiers

10.1038/BJP.2008.39

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Europe PubMed Central

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3 January 2020

PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18297104%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18297104%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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