(Q39521033)

12 September 2017

The Role of FoxC2 Transcription Factor in Tumor Angiogenesis (English)

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12 September 2017

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Tsutomu Kume

1

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12 September 2017

language of work or name

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16 November 2011

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12 September 2017

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12 September 2017

2012

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12 September 2017

204593

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Creative Commons Attribution 3.0 Unported

12 September 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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The cooperative roles of Foxc1 and Foxc2 in cardiovascular development.

12 September 2017

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The Foxc2 transcription factor regulates tumor angiogenesis

12 September 2017

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12 September 2017

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12 September 2017

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Origin and function of tumor stroma fibroblasts

12 September 2017

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Mesenchymal-epithelial transition in epithelial response to injury: the role of Foxc2

12 September 2017

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12 September 2017

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FoxM1 is a general target for proteasome inhibitors

12 September 2017

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Foxc2 transcription factor as a regulator of angiogenesis via induction of integrin beta3 expression

12 September 2017

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12 September 2017

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Foxc2 transcription factor: a newly described regulator of angiogenesis

12 September 2017

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Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors

12 September 2017

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FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells

12 September 2017

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The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

12 September 2017

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Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells

12 September 2017

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Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

12 September 2017

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The epithelial-mesenchymal transition generates cells with properties of stem cells

12 September 2017

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Role of platelet-derived growth factors in physiology and medicine

12 September 2017

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Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration

12 September 2017

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Forkhead transcription factors and cardiovascular biology

12 September 2017

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The emerging roles of forkhead box (Fox) proteins in cancer

12 September 2017

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Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells

12 September 2017

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Autocrine VEGF signaling is required for vascular homeostasis

12 September 2017

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Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102

12 September 2017

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Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers

12 September 2017

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Molecular mechanisms of lymphatic vascular development

12 September 2017

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FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

12 September 2017

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A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment

12 September 2017

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Comparative genomics of vertebrate Fox cluster loci

12 September 2017

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Lineage dependency and lineage-survival oncogenes in human cancer

12 September 2017

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The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development

12 September 2017

1 reference

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12 September 2017

Fibroblasts in cancer

1 reference

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Angiogenesis as a therapeutic target

12 September 2017

1 reference

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Angiogenesis in life, disease and medicine

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

12 September 2017

1 reference

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The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Gene expression profiling revealed novel mechanism of action of Taxotere and Furtulon in prostate cancer cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Imaging of angiogenesis: from microscope to clinic

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Forkhead transcription factors: key players in development and metabolism

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Unified nomenclature for the winged helix/forkhead transcription factors

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

12 September 2017

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Roles for the winged helix transcription factors MF1 and MFH1 in cardiovascular development revealed by nonallelic noncomplementation of null alleles

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Essential roles of the winged helix transcription factor MFH-1 in aortic arch patterning and skeletogenesis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Five years on the wings of fork head

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

The origin of the cancer cell: oncogeny reverses phylogeny

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Molecular characterization of TGFbeta-induced epithelial-mesenchymal transition in normal finite lifespan human mammary epithelial cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

p120-catenin is transcriptionally downregulated by FOXC2 in non-small cell lung cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Gene expression profiling revealed novel molecular targets of docetaxel and estramustine combination treatment in prostate cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

SIRT1 controls endothelial angiogenic functions during vascular growth

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Foxc2 overexpression enhances benefit of endothelial progenitor cells for inhibiting neointimal formation by promoting CXCR4-dependent homing.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

FOXC2 is a novel prognostic factor in human esophageal squamous cell carcinoma.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

FOXC2 haploinsufficient mice are a model for human autosomal dominant lymphedema-distichiasis syndrome

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228356

The role of ets factors in tumor angiogenesis

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F204593

FOXO1A Is a Candidate for the 13q14 Tumor Suppressor Gene Inhibiting Androgen Receptor Signaling in Prostate Cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F204593

Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F204593

Tumor induction of VEGF promoter activity in stromal cells

21 January 2018

1 reference

12 December 2020

Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248

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12 December 2020

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice

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12 December 2020

Identification of fibroblast heterogeneity in the tumor microenvironment

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12 December 2020

Identifiers

DOI

10.1155/2012/204593

1 reference

release_rpeqml3js5dexhmx4kc4wpnczy

12 September 2017

0 references

1 reference

12 September 2017

PubMed publication ID

22174714

1 reference