(Q39531590)

12 September 2017

title

Challenges in drug discovery for novel antifilarials (English)

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12 September 2017

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Simon Townson

1

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12 September 2017

Bernadette Ramirez

2

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12 September 2017

Foluke Fakorede

3

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12 September 2017

Marie-Annick Mouries

4

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12 September 2017

Solomon Nwaka

5

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12 September 2017

language of work or name

English

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publication date

1 October 2007

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Expert Opinion on Drug Discovery

12 September 2017

published in

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12 September 2017

volume

2

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12 September 2017

issue

s1

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12 September 2017

page(s)

S63-73

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Control of onchocerciasis today: status and challenges.

12 September 2017

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Mass drug treatment for lymphatic filariasis and onchocerciasis

21 January 2018

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Evaluation of microfilaricidal effects in the cornea from topically applied drugs in ocular onchocerciasis: Trials with levamisole and mebendazole

21 January 2018

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Treatment strategies underpinning the global programme to eliminate lymphatic filariasis

21 January 2018

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Control of onchocerciasis

21 January 2018

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Towards the elimination of onchocerciasis

21 January 2018

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APOC's strategy of community-directed treatment with ivermectin (CDTI) and its potential for providing additional health services to the poorest populations. African Programme for Onchocerciasis Control

21 January 2018

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Progress towards, and challenges for, the elimination of filariasis from Pacific-island communities

21 January 2018

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Mass treatment to eliminate filariasis in Papua New Guinea

21 January 2018

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An analysis of the safety of the single dose, two drug regimens used in programmes to eliminate lymphatic filariasis

21 January 2018

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The Mectizan Donation Program - highlights from 2005.

21 January 2018

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The role of albendazole in programmes to eliminate lymphatic filariasis

21 January 2018

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Partnership and promise: evolution of the African river-blindness campaigns

21 January 2018

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Current status and future prospects of the Global Lymphatic Filariasis Programme

21 January 2018

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Impact of ivermectin on illness and disability associated with onchocerciasis

21 January 2018

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New strategies to combat filariasis

21 January 2018

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Optimising the benefits of anthelmintic treatment in children

21 January 2018

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Macrofilaricides and onchocerciasis control, mathematical modelling of the prospects for elimination

21 January 2018

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Model-based analysis of trial data: microfilaria and worm-productivity loss after diethylcarbamazine-albendazole or ivermectin-albendazole combination therapy against Wuchereria bancrofti.

21 January 2018

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Drug resistance in human helminths: current situation and lessons from livestock

21 January 2018

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Is anthelmintic resistance a concern for heartworm control? What can we learn from the human filariasis control programs?

21 January 2018

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Foreword: towards markers for anthelmintic resistance in helminths of importance in animal and human health.

21 January 2018

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Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two-phase epidemiological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Ivermectin resistance and overview of the Consortium for Anthelmintic Resistance SNPs.

21 January 2018

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Successful vaccination against Onchocerca ochengi infestation in cattle using live Onchocerca volvulus infective larvae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Antiparasitic properties of medicinal plants and other naturally occurring products

21 January 2018

1 reference

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Antibiotics and Wolbachia in filarial nematodes: antifilarial activity of rifampicin, oxytetracycline and chloramphenicol against Onchocerca gutturosa, Onchocerca lienalis and Brugia pahangi

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Depletion of wolbachia endobacteria in Onchocerca volvulus by doxycycline and microfilaridermia after ivermectin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Vaccination against filarial nematodes with irradiated larvae provides long-term protection against the third larval stage but not against subsequent life cycle stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

The larval specific lymphatic filarial ALT-2: induction of protection using protein or DNA vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Novel phage display-based subtractive screening to identify vaccine candidates of Brugia malayi

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Towards a recombinant antigen vaccine against Onchocerca volvulus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Development of a recombinant antigen vaccine against infection with the filarial worm Onchocerca volvulus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Identification of potential vaccine and drug target candidates by expressed sequence tag analysis and immunoscreening of Onchocerca volvulus larval cDNA libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Final report of the Conference on the eradicability of Onchocerciasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Endosymbiotic bacteria in worms as targets for a novel chemotherapy in filariasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Onchocerca parasites and Wolbachia endosymbionts: evaluation of a spectrum of antibiotic types for activity against Onchocerca gutturosa in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Antibiotics which target the Wolbachia endosymbionts of filarial parasites: a new strategy for control of filariasis and amelioration of pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: a double-blind, randomised placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

A randomized, double-blind clinical trial of a 3-week course of doxycycline plus albendazole and ivermectin for the treatment of Wuchereria bancrofti infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Veterinary anthelmintics: old and new.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

From discovery to development: current industry perspectives for the development of novel methods of helminth control in livestock

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Ivermectin: uses and impact 20 years on.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

TDR collaboration with the pharmaceutical industry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Drug discovery and beyond: the role of public-private partnerships in improving access to new malaria medicines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Public-private partnership: from there to here

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Public-private partnerships: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Innovative lead discovery strategies for tropical diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Onchocerca gutturosa and O. volvulus: studies on the viability and drug responses of cryopreserved adult worms in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Differential effects of diethylcarbamazine, tetracycline and the combination on Brugia pahangi adult females in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Macrofilaricidal and microfilaricidal effects of Neurolaena lobata, a Guatemalan medicinal plant, on Brugia pahangi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

The lymphatic pathology of chronic Brugia pahangi infection in the dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Animal models for the study of immunity in human filariasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Chemotherapy for lymphatic filariasis: progress but not perfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

RNAi-based discovery and validation of new drug targets in filarial nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

Comparison of the sensitivity of different geographical races of Onchocerca volvulus microfilariae to ivermectin: studies in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

CHEMOTHERAPY OF ONCHOCERCIASIS: A CONTROLLED COMPARISON OF MEBENDAZOLE, LEVAMISOLE, AND DIETHYLCARBAMAZINE

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2.S1.S63

10.1517/17460441.2.S1.S63

21 January 2018

Identifiers

DOI

1 reference

12 September 2017

1 reference