(Q39532636)

English

Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination.

scientific article published on June 2011

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scholarly article

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2 February 2020

Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination (English)

1 reference

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2 February 2020

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2 February 2020

author name string

Michele Tavecchio

1

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2 February 2020

Joanne M Munck

2

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2 February 2020

Celine Cano

3

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2 February 2020

David R Newell

4

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2 February 2020

publication date

1 June 2011

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2 February 2020

Cancer Chemotherapy and Pharmacology

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2 February 2020

69

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2 February 2020

1

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2 February 2020

155-164

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2 February 2020

https://scigraph.springernature.com/pub.10.1007/s00280-011-1662-4

0 references

Choreography of recombination proteins during the DNA damage response

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Mechanisms of double-strand break repair in somatic mammalian cells

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Mechanism and regulation of class switch recombination

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

The SCID mouse mutant: definition, characterization, and potential uses

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

The DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

DNA-dependent protein kinase is a therapeutic target and an indicator of poor prognosis in B-cell chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441.

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Detection of ATM gene mutation in human glioma cell line M059J by a rapid frameshift/stop codon assay in yeast.

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

TGF-beta induces degradation of TAL1/SCL by the ubiquitin-proteasome pathway through AKT-mediated phosphorylation.

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Activation and regulation of ATM kinase activity in response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

DNA-PKcs and ATM co-regulate DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Poly(ADP-Ribose) polymerase-1 and DNA-dependent protein kinase have equivalent roles in double strand break repair following ionizing radiation

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Effects of novel inhibitors of poly(ADP-ribose) polymerase-1 and the DNA-dependent protein kinase on enzyme activities and DNA repair.

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

Radiosensitizing effects of gefitinib at different administration times in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1662-4

21 January 2018

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