(Q39539389)

12 September 2017

title

Shogaols at proapoptotic concentrations induce G(2)/M arrest and aberrant mitotic cell death associated with tubulin aggregation (English)

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12 September 2017

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Fei-Fei Gan

1

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12 September 2017

Amrita A Nagle

2

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12 September 2017

Xiaohui Ang

3

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12 September 2017

Olivia Huixian Ho

4

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12 September 2017

Sock-Hoon Tan

5

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12 September 2017

Hong Yang

6

1 reference

12 September 2017

Wai-Keung Chui

7

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12 September 2017

Eng-Hui Chew

8

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12 September 2017

publication date

1 August 2011

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12 September 2017

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12 September 2017

volume

16

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12 September 2017

issue

8

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12 September 2017

page(s)

856-867

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https://scigraph.springernature.com/pub.10.1007/s10495-011-0611-3

12 September 2017

exact match

0 references

cites work

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Microtubule assembly dynamics: an attractive target for anticancer drugs

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21 January 2018

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Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research

21 January 2018

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Diarylheptanoids from the rhizomes of Zingiber officinale

21 January 2018

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Cytotoxic and apoptotic activities of diarylheptanoids and gingerol-related compounds from the rhizome of Chinese ginger

21 January 2018

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Fresh organically grown ginger (Zingiber officinale): composition and effects on LPS-induced PGE2 production.

21 January 2018

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Commercially processed dry ginger (Zingiber officinale): composition and effects on LPS-stimulated PGE2 production

21 January 2018

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6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages

21 January 2018

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6-Shogaol reduced chronic inflammatory response in the knees of rats treated with complete Freund's adjuvant

21 January 2018

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6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase-9 expression via blockade of nuclear factor-κB activation

21 January 2018

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Anti-invasion effects of 6-shogaol and 6-gingerol, two active components in ginger, on human hepatocarcinoma cells

21 January 2018

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6-shogaol (alkanone from ginger) induces apoptotic cell death of human hepatoma p53 mutant Mahlavu subline via an oxidative stress-mediated caspase-dependent mechanism

21 January 2018

1 reference

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6-Shogaol induces apoptosis in human colorectal carcinoma cellsviaROS production, caspase activation, and GADD 153 expression

21 January 2018

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Induction of apoptosis by [8]-shogaol via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia cells.

21 January 2018

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Specific reaction of alpha,beta-unsaturated carbonyl compounds such as 6-shogaol with sulfhydryl groups in tubulin leading to microtubule damage

21 January 2018

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Side-chain length is important for shogaols in protecting neuronal cells from beta-amyloid insult

21 January 2018

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Cancer preventive isothiocyanates induce selective degradation of cellular alpha- and beta-tubulins by proteasomes

21 January 2018

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Increased growth inhibitory effects on human cancer cells and anti-inflammatory potency of shogaols from Zingiber officinale relative to gingerols.

21 January 2018

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Cytotoxic components from the dried rhizomes of Zingiber officinale Roscoe

21 January 2018

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Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe.

21 January 2018

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Mitotic kinases as regulators of cell division and its checkpoints

21 January 2018

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Checking out the G(2)/M transition.

21 January 2018

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Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

21 January 2018

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Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1.

21 January 2018

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Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation

21 January 2018

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21 January 2018

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Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics

21 January 2018

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Tubulin dynamics in cultured mammalian cells

21 January 2018

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Spindle microtubule dynamics in sea urchin embryos: analysis using a fluorescein-labeled tubulin and measurements of fluorescence redistribution after laser photobleaching

21 January 2018

1 reference

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10.1007/S10495-011-0611-3

21 January 2018

Identifiers

DOI

1 reference

12 September 2017

1 reference