(Q39540382)

English

Misoprostol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of peptic ulcer disease

scientific article published on January 1987

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

1 reference

Europe PubMed Central

Misoprostol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of peptic ulcer disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

author name string

J P Monk

1

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

S P Clissold

2

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

publication date

1 January 1987

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

33

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

1-30

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

https://scigraph.springernature.com/pub.10.2165/00003495-198733010-00001

0 references

Smoking impairs therapeutic gastric inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Misoprostol, a synthetic prostaglandin E1 analogue, in the treatment of duodenal ulcers. A double-blind, cimetidine-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and pharmacokinetic studies of misoprostol

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of misoprostol and cimetidine on gastric cell labeling index

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of the position of the side chain hydroxy group on the gastric antisecretory and antiulcer actions of E1 prostaglandin analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastrointestinal cytoprotection by prostaglandins

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin-stimulated gastric mucus secretion in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of aspirin and other non-steroid anti-inflammatory/analgesic drugs on gastro-intestinal mucus glycoprotein biosynthesis in vivo: Relationship to ulcerogenic actions

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of cigarette smoking on gastrointestinal physiology and non-neoplastic digestive disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandins and the gastrointestinal mucosa: are they important in its function, disease, or treatment?

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of prostaglandins against gastric mucosal damage: current knowledge and proposed mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multicenter international controlled comparison of two dosage regimens of misoprostol with cimetidine in treatment of gastric ulcer in outpatients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative gastric antisecretory and antiulcer effects of prostaglandin E1 and its methyl ester in animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric bicarbonate secretion in humans. Effect of pentagastrin, bethanechol, and 11,16,16-trimethyl prostaglandin E2

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Misoprostol clinical pharmacology. Establishment of activity in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the immune response by prostaglandins

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandins as hormones

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative inhibition of coffee-induced gastric acid secretion employing misoprostol and cimetidine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing the safety of drugs for the long-term treatment of peptic ulcers

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of mucus and nonparietal cell secretion by the E2 prostaglandins

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Acute injury to the gastric mucosa by acetylsalicylic acid. A comparative endoscopic study in man with oral prostaglandin analogs, omeprazole and ranitidine]

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric protection by misoprostol against 1300 mg of aspirin. An endoscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of duodenal bicarbonate secretion by misoprostol

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric blood flow and the gastric mucosal barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric gel mucus thickness: effect of distention, 16,16-dimethyl prostaglandin e2, and carbenoxolone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of SC-29333, an inhibitor of gastric secretion, on canine gastric mucosal blood flow and serum gastrin levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric morphology in ulcer patients receiving misoprostol

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Effects of misoprostol, (+/-)-methyl (11 alpha, 13E)-11, 16-dihydroxy-16-methyl-9-oxoprost-13-en-l-oate, on various gastric and duodenal lesions in rats]

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin E1 (Misoprostol) overcomes the adverse effect of chronic cigarette smoking on duodenal ulcer healing

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SC-29333: a potent inhibitor of canin gastric secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of absolute ethanol, misoprostol, cimetidine, and phosphate buffer on the morphology of rat gastric mucosae

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of gastric ulcer. What is old and what is new.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiology and pharmacology of prostaglandins

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human gastric mucosal adenylate cyclase activity: effects of various cytoprotective prostaglandins

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric bicarbonate secretion: effect of topical and intravenous 16,16-dimethyl prostaglandin E2

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructure of tight junctions in prostaglandin-exposed rat stomach

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of correlation between mucus gel thickness and gastric cytoprotection in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic Antral Gastritis in Duodenal Ulcer

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defects in prostaglandin synthesis and metabolism in ulcer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16, 16-dimethyl PGE2. Intravenous, oral and intrajejunal administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Misoprostol and cimetidine in the treatment of duodenal ulcer. A multicenter Swiss double-blind study]

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A double-blind study of prophylactic effect of misoprostol on lesions of gastric and duodenal mucosa induced by oral administration of tolmetin in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of misoprostol, an antiulcer prostaglandin, on serum gastrin in patients with duodenal ulcer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol induced duodenal lesions in man. Protective effect of prostaglandin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overview of clinical safety with misoprostol

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of synthetic prostaglandin E1 analog on aspirin-induced gastric bleeding and secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of cytoprotection against ethanol-induced injury in gastric mucosa pretreated with misoprostol, cimetidine, or placebo

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of aspirin-induced fecal blood loss with low-dose misoprostol tablets in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active smoking depresses prostaglandin synthesis in human gastric mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Misoprostol, a synthetic PGE1 analog, in the treatment of duodenal ulcers. A multicenter double-blind study

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Misoprostol preclinical pharmacology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative mucosal protective properties of misoprostol, cimetidine, and sucralfate

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation and characterization of prostaglandins in the human gastrointestinal tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandins, thromboxanes and leukotrienes in clinical medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Healing of benign gastric ulcer. A placebo-controlled comparison of two dosage regimens of misoprostol, a synthetic analog of prostaglandin E1

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytoprotection by a synthetic prostaglandin against ethanol-induced gastric mucosal damage. A double-blind endoscopic study in human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Misoprostol in the treatment of duodenal ulcer. A multicenter double-blind placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostanoid synthesis by cultured gastric and duodenal mucosa: Possible role in the pathogenesis of duodenal ulcer

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation by intragastrically administered E2prostaglandins of human gastric mucus output

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of misoprostol on gastric acid and mucus secretion in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a prostaglandin E1 derivative, SC-29333, and aspirin on gastric ionic fluxes and potential difference in dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antisecretory drugs and gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of prostaglandin E 1 on canine gastric acid secretion and gastric mucosal blood flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Duodenal bicarbonate secretion in humans. Role of prostaglandins

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin E1 (misoprostol) and S-adenosylmethionine in the prevention of hemorrhagic gastritis induced by aspirin in the human. Endoscopic, histologic and histochemical study

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of non-steroidal anti-inflammatory drugs and prostaglandins on alkali secretion by rabbit gastric fundus in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Misoprostol-induced increases in adherent gastric mucus thickness and luminal mucus output

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multicenter international controlled comparison of two dosage regimes of misoprostol and cimetidine in the treatment of duodenal ulcer in out-patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytoprotective effects of (+/-)-15-deoxy-16-alpha, beta-hydroxy-16-methyl PGE1 methyl ester (sc-29333) versus aspirin-shock gastric ulcerogenesis in the dog

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of 15(R)-15-methyl prostaglandin E2 (arbaprostil) on the healing of duodenal ulcer: a double-blind multicenter study

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adherent and soluble mucus in the stomach and duodenum

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical toxicology profile of misoprostol

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric mucosal damage in sepsis--effects of pretreatment with a synthetic prostaglandin E1 analogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of food stimulated acid secretion by misoprostol, an orally active synthetic E1 analogue prostaglandin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of (3H)prostaglandin E1 to putative receptors linked to adenylate cyclase of cultured cell clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric cytoprotection by epidermal growth factor. Role of endogenous prostaglandins and DNA synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociated effects of misoprostol on gastric acid secretion and mucosal blood flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of synthetic prostaglandin E1 analog on gastric emptying of meals in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of endogenous gastric prostanoids in the pathogenesis and therapy of duodenal ulcer

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of E prostaglandins on canine gastric potential difference

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marked inhibition of gastric secretion by two prostaglandin analogs given orally to man

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overview of misoprostol clinical experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Summary of the 29th meeting of the Gastrointestinal Drugs Advisory Committee, Food and Drug Administration--June 10, 1985

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of misoprostol (twice daily dosage) in acute healing of duodenal ulcer. A multicenter double-blind controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of nocturnal gastric secretion in normal human volunteers by misoprostol: a synthetic prostaglandin E1 methyl ester analog

1 reference

https://pubmed.ncbi.nlm.nih.gov/3102205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003495-198733010-00001

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39540382&oldid=2143849680"