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CG8577 gene product from transcript CG8577-RB Dmel_CG8577
protein found in Drosophila melanogaster
PGRP-SC1b-PA
CG8577-PA
PGRP-SC1b
Peptidoglycan-recognition protein-SC1b precursor
PGRP-SC1b-PB
CG8577-PB
CG8577 gene product from transcript CG8577-RB
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
28 March 2018
UniProt protein ID
C0HK98
subclass of
protein
1 reference
stated in
UniProt
retrieved
28 February 2018
UniProt protein ID
C0HK98
part of
Peptidoglycan recognition protein, PGRP-S
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/C0HK98
N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/C0HK98
Peptidoglycan recognition protein family domain, metazoa/bacteria, protein family
1 reference
based on heuristic
inferred from protein domain or family
N-acetylmuramoyl-L-alanine amidase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
28 February 2018
UniProt protein ID
C0HK98
encoded by
PGRP-SC1b
1 reference
stated in
UniProt
retrieved
28 February 2018
UniProt protein ID
C0HK98
PGRP-SC1a
1 reference
stated in
UniProt
retrieved
28 February 2018
UniProt protein ID
C0HK98
molecular function
zinc ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
N-acetylmuramoyl-L-alanine amidase activity
determination method
IEA
ISS
3 references
retrieved
16 July 2018
stated in
A scavenger function for a Drosophila peptidoglycan recognition protein.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=C0HK98&geneProductId=UniProtKB:C0HK98
determination method
ISS
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=C0HK98&geneProductId=UniProtKB:C0HK98
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=C0HK98&geneProductId=UniProtKB:C0HK98
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
peptidoglycan binding
determination method
IEA
ISS
NAS
4 references
retrieved
16 July 2018
stated in
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=C0HK98&geneProductId=UniProtKB:C0HK98
determination method
NAS
retrieved
16 July 2018
stated in
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=C0HK98&geneProductId=UniProtKB:C0HK98
determination method
ISS
retrieved
16 July 2018
stated in
A scavenger function for a Drosophila peptidoglycan recognition protein.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=C0HK98&geneProductId=UniProtKB:C0HK98
determination method
ISS
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=C0HK98&geneProductId=UniProtKB:C0HK98
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
N-acetylmuramoyl-L-alanine amidase activity
determination method
IBA
IEA
ISS
4 references
retrieved
8 April 2019
stated in
A scavenger function for a Drosophila peptidoglycan recognition protein.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IBA
peptidoglycan immune receptor activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IBA
peptidoglycan binding
determination method
IBA
IEA
ISS
NAS
5 references
retrieved
8 April 2019
stated in
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
NAS
retrieved
8 April 2019
stated in
A scavenger function for a Drosophila peptidoglycan recognition protein.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
ISS
retrieved
8 April 2019
stated in
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IBA
cell component
extracellular region
determination method
IEA
ISS
NAS
4 references
retrieved
8 April 2019
stated in
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
NAS
retrieved
8 April 2019
stated in
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
ISS
retrieved
8 April 2019
stated in
Peptidoglycan recognition proteins: on and off switches for innate immunity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
extracellular space
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IBA
biological process
immune system process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
immune response
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
ISS
peptidoglycan catabolic process
determination method
IEA
ISS
NAS
3 references
retrieved
8 April 2019
stated in
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
NAS
retrieved
8 April 2019
stated in
A scavenger function for a Drosophila peptidoglycan recognition protein.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
innate immune response
determination method
IEA
NAS
3 references
retrieved
8 April 2019
stated in
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
C0HK98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
negative regulation of innate immune response
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IDA
pattern recognition receptor signaling pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IEA
antimicrobial humoral response
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IBA
negative regulation of natural killer cell differentiation involved in immune response
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IBA
defense response to Gram-positive bacterium
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=C0HK98&geneProductId=UniProtKB:C0HK98
determination method
IBA
positive regulation of Toll signaling pathway
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The peptidoglycan recognition protein PGRP-SC1a is essential for Toll signaling and phagocytosis of Staphylococcus aureus in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IMP
positive regulation of phagocytosis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The peptidoglycan recognition protein PGRP-SC1a is essential for Toll signaling and phagocytosis of Staphylococcus aureus in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IMP
defense response to Gram-positive bacterium
determination method
IBA
IMP
2 references
retrieved
8 April 2019
stated in
The peptidoglycan recognition protein PGRP-SC1a is essential for Toll signaling and phagocytosis of Staphylococcus aureus in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IMP
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C0HK98
determination method
IBA
has part(s)
Peptidoglycan recognition protein family domain, metazoa/bacteria
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/C0HK98
N-acetylmuramoyl-L-alanine amidase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/C0HK98
Identifiers
RefSeq protein ID
NP_001286209
1 reference
stated in
NCBI Gene
retrieved
16 March 2018
Entrez Gene ID
35861
NP_610409
1 reference
stated in
NCBI Gene
retrieved
16 March 2018
Entrez Gene ID
35861
NP_610407
1 reference
stated in
NCBI Gene
retrieved
13 April 2018
Entrez Gene ID
35859
UniProt protein ID
C0HK98
1 reference
stated in
UniProt
retrieved
28 February 2018
UniProt protein ID
C0HK98
Ensembl protein ID
FBpp0308436
1 reference
stated in
ensembl Release 92
Ensembl protein ID
FBpp0308436
FBpp0087787
1 reference
stated in
ensembl Release 92
Ensembl protein ID
FBpp0087787
FBpp0087786
1 reference
stated in
ensembl Release 92
Ensembl protein ID
FBpp0087786
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