(Q39547016)

12 September 2017

title

Modification of human embryonic stem cell-derived dendritic cells with mRNA for efficient antigen presentation and enhanced potency (English)

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human embryonic stem cell

12 September 2017

main subject

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Kevin P Nishimoto

1

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12 September 2017

Su-Yi Tseng

series ordinal

2

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12 September 2017

Jane S Lebkowski

series ordinal

3

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12 September 2017

Anita Reddy

series ordinal

4

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12 September 2017

publication date

1 May 2011

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12 September 2017

published in

Regenerative Medicine

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12 September 2017

volume

6

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12 September 2017

issue

3

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12 September 2017

page(s)

303-318

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The dendritic cell system and its role in immunogenicity

12 September 2017

cites work

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Tolerogenic dendritic cells

21 January 2018

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The use of dendritic cells in cancer immunotherapy

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Tolerogenic dendritic cells and the quest for transplant tolerance

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The first 1000 dendritic cell vaccinees.

21 January 2018

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Presentation of tumour antigens by dendritic cells and challenges faced.

21 January 2018

1 reference

The evolving role of dendritic cells in cancer therapy

21 January 2018

1 reference

Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro

21 January 2018

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Generation of immunogenic dendritic cells from human embryonic stem cells without serum and feeder cells.

21 January 2018

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Differentiation of human embryonic stem cells into immunostimulatory dendritic cells under feeder-free culture conditions.

21 January 2018

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Directed differentiation of human embryonic stem cells into functional dendritic cells through the myeloid pathway

21 January 2018

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Genetically manipulated human embryonic stem cell-derived dendritic cells with immune regulatory function

21 January 2018

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Human embryonic stem cell (hES) derived dendritic cells are functionally normal and are susceptible to HIV-1 infection

21 January 2018

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Dendritic cells, new tools for vaccination

21 January 2018

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Viral vectors for inducing CD8+ T cell responses

21 January 2018

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Interleukin-12 improves cytotoxicity of natural killer cells via upregulated expression of NKG2D.

21 January 2018

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Tumor cell loaded type-1 polarized dendritic cells induce Th1-mediated tumor immunity

21 January 2018

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Immunization of patients with the hTERT:540-548 peptide induces peptide-reactive T lymphocytes that do not recognize tumors endogenously expressing telomerase

21 January 2018

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Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.

21 January 2018

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The development of 'feeder' cells for the preparation of clinical grade hES cell lines: challenges and solutions.

21 January 2018

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A comparative analysis of serum and serum-free media for generation of clinical grade DCs.

21 January 2018

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Differential effects of autologous serum on CD34(+) or monocyte-derived dendritic cells

21 January 2018

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Serum concentration of the growth medium markedly affects monocyte-derived dendritic cells' phenotype, cytokine production profile and capacities to stimulate in MLR.

21 January 2018

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Xeno-free derivation and culture of human embryonic stem cells: current status, problems and challenges.

21 January 2018

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Human dendritic cell maturation by adenovirus transduction enhances tumor antigen-specific T-cell responses

21 January 2018

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Human PBMC-derived dendritic cells transduced with an adenovirus vectorinduce cytotoxic T-lymphocyte responses against a vector-encoded antigen in vitro.

21 January 2018

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Dendritic cells reconstituted with human telomerase gene induce potent cytotoxic T-cell response against different types of tumors

21 January 2018

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Differential lysis of tumors by polyclonal T cell lines and T cell clones specific for hTERT.

21 January 2018

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IL-12 in conjunction with dendritic cells enhances antiviral CD8+ CTL responses in vitro

21 January 2018

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Poly(I:C) used for human dendritic cell maturation preserves their ability to secondarily secrete bioactive IL-12.

21 January 2018

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Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production

21 January 2018

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Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells

21 January 2018

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Dendritic cells transfected with interleukin-12 and tumor-associated antigen messenger RNA induce high avidity cytotoxic T cells.

21 January 2018

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Engineered expression of the Coxsackie B and adenovirus receptor (CAR) in human dendritic cells enhances recombinant adenovirus-mediated gene transfer.

21 January 2018

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Adenoviral-encoded antigens are presented efficiently by a subset of dendritic cells expressing high levels of alpha(v)beta3 integrins

21 January 2018

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Electroporation of immature and mature dendritic cells: implications for dendritic cell-based vaccines

21 January 2018

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Generation of an optimized polyvalent monocyte-derived dendritic cell vaccine by transfecting defined RNAs after rather than before maturation.

21 January 2018

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The immunogenicity of the hTERT540-548 peptide in cancer

21 January 2018

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Lack of tumor recognition by hTERT peptide 540-548-specific CD8(+) T cells from melanoma patients reveals inefficient antigen processing.

21 January 2018

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Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs.

21 January 2018

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Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination

21 January 2018

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Dendritic cell vaccination combined with CTLA4 blockade in patients with metastatic melanoma

21 January 2018

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A randomized therapeutic vaccine trial of canarypox-HIV-pulsed dendritic cells vs. canarypox-HIV alone in HIV-1-infected patients on antiretroviral therapy

21 January 2018

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Phase Ib trial assessing autologous, tumor-pulsed dendritic cells as a vaccine administered with or without IL-2 in patients with metastatic melanoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/RME.11.19

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12 September 2017

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