(Q39550909)

English

The use of aminoglycoside derivatives to study the mechanism of aminoglycoside 6'-N-acetyltransferase and the role of 6'-NH2 in antibacterial activity

scientific article published on 11 February 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

The use of aminoglycoside derivatives to study the mechanism of aminoglycoside 6'-N-acetyltransferase and the role of 6'-NH2 in antibacterial activity (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

1 reference

ChEBI release 2020-05-28

author name string

Xuxu Yan

1

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Feng Gao

2

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Sirilata Yotphan

3

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Parseh Bakirtzian

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Karine Auclair

5

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

language of work or name

0 references

publication date

11 February 2007

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Bioorganic & Medicinal Chemistry

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

15

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

8

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

2944-2951

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Discovery of non-carbohydrate inhibitors of aminoglycoside-modifying enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Improving on nature: antibiotics that target the ribosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Synthesis of a library of stereo- and regiochemically diverse aminoglycoside derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Aminoglycoside and its derivatives as ligands to target the ribosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallography

1 reference

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14 September 2017

Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding a site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Aminoglycoside antibiotics, neamine and its derivatives as potent inhibitors for the RNA-protein interactions derived from HIV-1 activators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Aminoglycoside-modifying enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Overexpression and characterization of the chromosomal aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Interaction of antibiotics with functional sites in 16S ribosomal RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Conformational constraint as a means for understanding RNA-aminoglycoside specificity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

14 September 2017

Synthesis of a tight-binding, multisubstrate analog inhibitor of gentamicin acetyltransferase I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

25 September 2017

Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

21 August 2018

Molecular recognition of RNA by neomycin and a restricted neomycin derivative.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

21 August 2018

Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

21 August 2018

Monitoring molecular recognition of the ribosomal decoding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

21 August 2018

A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

21 August 2018

Molecular mechanism of the enterococcal aminoglycoside 6'-N-acetyltransferase': role of GNAT-conserved residues in the chemistry of antibiotic inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

21 August 2018

Design of novel antibiotics that bind to the ribosomal acyltransfer site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5173354

21 August 2018

Tethered bisubstrate derivatives as probes for mechanism and as inhibitors of aminoglycoside 3'-phosphotransferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17317190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of neamine as a molecular template: inactivation of bacterial antibiotic resistance enzyme aminoglycoside 3'-phosphotransferase type IIa

1 reference

https://pubmed.ncbi.nlm.nih.gov/17317190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regio- and Chemoselective 6′-N-Derivatization of Aminoglycosides: Bisubstrate Inhibitors as Probes To Study Aminoglycoside 6′-N-Acetyltransferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17317190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and Structure−Activity Relationships of Truncated Bisubstrate Inhibitors of Aminoglycoside 6‘-N-Acetyltransferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17317190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BMC.2007.02.009

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

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