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The proto-oncogene c-myc is a direct target gene of Epstein-Barr virus nuclear antigen 2.
scientific article published on May 1999
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
title
The proto-oncogene c-myc is a direct target gene of Epstein-Barr virus nuclear antigen 2
(English)
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
main subject
Epstein–Barr virus
0 references
author name string
Kaiser C
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
Laux G
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
Eick D
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
Jochner N
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
Bornkamm GW
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
Kempkes B
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
language of work or name
English
0 references
publication date
1 May 1999
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
volume
73
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
page(s)
4481-4484
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
issue
5
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
cites work
An ATF/CRE element mediates both EBNA2-dependent and EBNA2-independent activation of the Epstein-Barr virus LMP1 gene promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
Epstein-Barr virus latent membrane protein (LMP1) is not sufficient to maintain proliferation of B cells but both it and activated CD40 can prolong their survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
c-myc activation renders proliferation of Epstein-Barr virus (EBV)-transformed cells independent of EBV nuclear antigen 2 and latent membrane protein 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
Epstein-Barr virus nuclear protein 2 (EBNA2) binds to a component of the human SNF-SWI complex, hSNF5/Ini1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
Epstein-Barr virus nuclear antigen 2-estrogen receptor fusion proteins transactivate viral and cellular genes and interact with RBP-J kappa in a conditional fashion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
The Epstein-Barr virus nuclear antigen 2 interacts with an EBNA2 responsive cis-element of the terminal protein 1 gene promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
EBNA-2 upregulation of Epstein-Barr virus latency promoters and the cellular CD23 promoter utilizes a common targeting intermediate, CBF1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
The Spi-1/PU.1 and Spi-B ets family transcription factors and the recombination signal binding protein RBP-J kappa interact with an Epstein-Barr virus nuclear antigen 2 responsive cis-element.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
The Epstein-Barr virus nuclear protein 2 acidic domain can interact with TFIIB, TAF40, and RPA70 but not with TATA-binding protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
Identification and characterization of an Epstein-Barr virus nuclear antigen 2-responsive cis element in the bidirectional promoter region of latent membrane protein and terminal protein 2 genes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
PU box-binding transcription factors and a POU domain protein cooperate in the Epstein-Barr virus (EBV) nuclear antigen 2-induced transactivation of the EBV latent membrane protein 1 promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
Epstein-Barr virus immortalizing genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
Regulation of protein function through expression of chimaeric proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
14 September 2017
Control of transcription by steroid hormones
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
25 September 2017
Epstein-Barr virus nuclear antigen 2 is a transcriptional suppressor of the immunoglobulin mu gene: implications for the expression of the translocated c-myc gene in Burkitt's lymphoma cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
25 September 2017
EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
25 September 2017
Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
25 September 2017
Epstein-Barr virus nuclear antigen 2 (EBNA2)-oestrogen receptor fusion proteins complement the EBNA2-deficient Epstein-Barr virus strain P3HR1 in transformation of primary B cells but suppress growth of human B cell lymphoma lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
25 September 2017
Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
15 June 2018
Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104340
retrieved
21 August 2018
Identifiers
PMCID
104340
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
PubMed ID
10196351
1 reference
stated in
Europe PubMed Central
PMCID
104340
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
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