(Q39553293)

13 September 2017

Use of the NP-40 detergent-mediated assay in discovery of inhibitors of beta-hematin crystallization (English)

1 reference

13 September 2017

Rebecca D Sandlin

1

1 reference

13 September 2017

Melissa D Carter

2

1 reference

13 September 2017

Patricia J Lee

3

1 reference

13 September 2017

Jennifer M Auschwitz

4

1 reference

13 September 2017

Susan E Leed

5

1 reference

13 September 2017

Jacob D Johnson

6

1 reference

13 September 2017

David W Wright

7

1 reference

13 September 2017

language of work or name

English

0 references

publication date

25 April 2011

1 reference

Antimicrobial Agents and Chemotherapy

13 September 2017

1 reference

13 September 2017

55

1 reference

13 September 2017

7

1 reference

13 September 2017

3363-3369

1 reference

The neutral lipid composition present in the digestive vacuole of Plasmodium falciparum concentrates heme and mediates β-hematin formation with an unusually low activation energy

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Chemical genetics of Plasmodium falciparum

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Thousands of chemical starting points for antimalarial lead identification

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Lipophilic mediated assays for beta-hematin inhibitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Crystallization of synthetic haemozoin (beta-haematin) nucleated at the surface of lipid particles

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Colorimetric high-throughput screen for detection of heme crystallization inhibitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Activity of piperaquine and other 4-aminoquinoline antiplasmodial drugs against chloroquine-sensitive and resistant blood-stages of Plasmodium falciparum. Role of beta-haematin inhibition and drug concentration in vacuolar water- and lipid-phases.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Food vacuole-associated lipid bodies and heterogeneous lipid environments in the malaria parasite, Plasmodium falciparum

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Hematin polymerization assay as a high-throughput screen for identification of new antimalarial pharmacophores

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

The structure of malaria pigment beta-haematin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

A comparison and analysis of several ways to promote haematin (haem) polymerisation and an assessment of its initiation in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

The pH of the digestive vacuole of Plasmodium falciparum is not associated with chloroquine resistance

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

A colorimetric high-throughput beta-hematin inhibition screening assay for use in the search for antimalarial compounds

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Standardization of the physicochemical parameters to assess in vitro the beta-hematin inhibitory activity of antimalarial drugs.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

A perspective on antimalarial action: effects of weak bases on Plasmodium falciparum

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Hematin-hematin self-association states involved in the formation and reactivity of the malaria parasite pigment, hemozoin

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Haemozoin (beta-haematin) biomineralization occurs by self-assembly near the lipid/water interface

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

The mechanism of beta-hematin formation in acetate solution. Parallels between hemozoin formation and biomineralization processes

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Involvement of lipids in ferriprotoporphyrin IX polymerization in malaria

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

Haem polymerization in malaria

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122397

21 August 2018

Identifiers

DOI

10.1128/AAC.00121-11

1 reference

13 September 2017

1 reference

13 September 2017

PubMed publication ID

21518844

1 reference