(Q39559476)

13 September 2017

Central role of hemoglobin degradation in mechanisms of action of 4-aminoquinolines, quinoline methanols, and phenanthrene methanols (English)

1 reference

13 September 2017

M Mungthin

1

1 reference

13 September 2017

P G Bray

series ordinal

2

1 reference

13 September 2017

R G Ridley

series ordinal

3

1 reference

13 September 2017

S A Ward

series ordinal

4

1 reference

13 September 2017

language of work or name

English

0 references

publication date

1 November 1998

1 reference

Antimicrobial Agents and Chemotherapy

13 September 2017

1 reference

13 September 2017

42

1 reference

13 September 2017

11

1 reference

13 September 2017

2973-2977

1 reference

The pathway of hemoglobin degradation in malaria parasites

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Relationship between antimalarial drug activity, accumulation, and inhibition of heme polymerization in Plasmodium falciparum in vitro.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Expression and characterisation of plasmepsin I from Plasmodium falciparum

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Quinoline antimalarials: mechanisms of action and resistance.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

On the molecular mechanism of chloroquine's antimalarial action

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Inverse correlation of sensitivity in vitro of Plasmodium falciparum to chloroquine and mefloquine in Ghana

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

The use of electron microscope autoradiography for examining the uptake and degradation of haemoglobin byPlasmodium berghei

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Antimalarial interaction with ferriprotoporphyrin IX monomer and its relationship to activity of the blood schizontocides.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Hemoglobin degradation in the human malaria pathogen Plasmodium falciparum: a catabolic pathway initiated by a specific aspartic protease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Studies of the disposition and metabolism of mefloquine HCl (WR 142,490), a quinolinemethanol antimalarial, in the rat. Limited studies with an analog, WR 30,090

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

The antimalarial drug mefloquine binds to membrane phospholipids

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Biochemical aspects of drug action and resistance in malaria parasites.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Haematin (haem) polymerization and its inhibition by quinoline antimalarials

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Quinoline resistance mechanisms in Plasmodium falciparum: the debate goes on.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Chloroquine: mechanism of drug action and resistance in Plasmodium falciparum

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

The relationship between the response of Plasmodium falciparum malaria to mefloquine in African children and its sensitivity in vitro

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

The chemotherapy of rodent malaria, XXVII Studies on mefloquine (WR 142,490)

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Plasmodium falciparum in Culture: Use of Outdated Erythrocytes and Description of the Candle Jar Method

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

COMPLEX FORMATION BETWEEN CHLOROQUINE AND FERRIHAEMIC ACID IN VITRO, AND ITS EFFECT ON THE ANTIMALARIAL ACTION OF CHLOROQUINE.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Access to hematin: the basis of chloroquine resistance.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Photoaffinity labeling of mefloquine-binding proteins in human serum, uninfected erythrocytes and Plasmodium falciparum-infected erythrocytes.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Novel bisquinoline antimalarials. Synthesis, antimalarial activity, and inhibition of haem polymerisation.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Plasmodium falciparum: effects of proteinase inhibitors on globin hydrolysis by cultured malaria parasites

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Effects of antimalarials and protease inhibitors on plasmodial hemozoin production

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

The malaria parasite monitored by photoacoustic spectroscopy

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

The relationship between the in vitro response of Plasmodium falciparum to chloroquine, quinine and mefloquine

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Mode of Action of Chloroquine on Plasmodium berghei and P. cynomolgi

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Morphological Effects of Chloroquine on Plasmodium berghei in Mice

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

In vitro response of Plasmodium falciparum to mefloquine. Studies conducted in West and East Africa

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

An ultrastructural study of the effects of mefloquine on malaria parasites

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Ultrastructure of Plasmodium falciparum "in vitro". II. Morphological patterns of different quinolines effects

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

A Method for Testing for Synergy with Any Number of Agents

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Malarial haemozoin/beta-haematin supports haem polymerization in the absence of protein

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105975

Plasmodium falciparum: differential sensitivity in vitro to E-64 (cysteine protease inhibitor) and Pepstatin A (aspartyl protease inhibitor)

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9797235

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of native falcipain, an enzyme involved in Plasmodium falciparum hemoglobin degradation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9797235

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The quinine-haemin interaction and its relationship to antimalarial activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9797235

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

13 September 2017

1 reference