(Q39567059)

13 September 2017

1 reference

title

Disposition of hexobarbital: 15 years of an intriguing model substrate (English)

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13 September 2017

van der Graaff M

1

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13 September 2017

Vermeulen NP

series ordinal

2

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13 September 2017

Breimer DD

series ordinal

3

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13 September 2017

language of work or name

English

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publication date

1 January 1988

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13 September 2017

Drug Metabolism Reviews

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13 September 2017

19

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13 September 2017

2

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13 September 2017

109-164

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Assessment of the drug metabolism capacity of the liver

13 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

The epoxide-diol pathway in the metabolism of hexobarbital in rat and man

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Disposition of hexobarbitone in healthy man: kinetics of parent drug and metabolites following oral administration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

The metabolic fate of 1',2'-epoxyhexobarbital in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Preparation, morphology and drug metabolism of isolated hepatotcyte and liver organ cultures from the human fetus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Dehydrogenation of Indanol by Rabbit Liver 3-Hydroxyhexobarbital Dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

5β-androstane-3α,17β-diol: An endogenous substrate for rabbit liver 3-hydroxyhexobarbital dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Interactions of the Hexobarbital Enantiomers with Rat Liver Microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Mechanisms in the potentiation and inhibition of pharmacological actions of hexobarbital and zoxazolamine by glycofurol.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Influence of surgical manipulations on hexobarbital effects in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Hepatic blood flow and enzyme induction in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Rapid and Selective Determination of Free Barbiturates by Gas Chromatography Using the Electrolytic Conductivity Detector

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Effects of chronic ethanol administration in the rat: Relative dependency on dietary lipids—III. In vivo tolerance to hexobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Effect of acetazolamide on barbiturate-induced sleeping time in mice. III. Pharmacokinetics of serum elimination and brain distribution.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Pharmacokinetics of hexobarbital in acute hepatitis and after apparent recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Species differences of mixed-function oxidase induction between rabbits and rats after pretreatment with polychlorinated biphenyls (PCB's)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Hexobarbital-binding, hydroxylation and hexobarbital-dependent hydrogen peroxide production in hepatic microsomes of guinea pig, rat and rabbit.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Hydroxylation of hexobarbital and benzo[a]pyrene by hepatic microsomes isolated from the fetal stumptailed monkey (Macaca arctoides). A developmental study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Oxidation of barbiturates and the glucuronidation of 1-napthol in perfused rat liver and in microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Effect of anesthesia on drug disposition in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Pharmacokinetic aspects of elimination from plasma and distribution to brain and liver of barbiturates in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Route- and dose-dependent pharmacokinetics of hexobarbitone in the rat: a re-evaluation of the use of sleeping times in metabolic studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Comparative physiologically based pharmacokinetics of hexobarbital, phenobarbital and thiopental in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Thiopental Pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Pharmacokinetics of hexobarbital in man after intravenous infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Differences in anaesthetic properties between the optical antipodes of hexobarbital in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Pharmacokinetics of the enantiomers of hexobarbital studied in the same intact rat and in the same isolated perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Correlation between the in vivo metabolism of hexobarbital and antipyrine in rats with a portacaval shunt.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Studies on the Different Metabolic Pathways of Antipyrine in Rats: Influence of Phenobarbital and 3-Methylcholanthrene Treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Hexobarbital sleeping time and drug metabolism in rats with ligated bile ducts--a lack of correlation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Assessment of Methods to Identify Sources of Interindividual Pharmacokinetic Variations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Purification and characterization of microsomal cytochrome P-450s

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Effect of beta-cyclodextrin on sleeping time induced by barbituric acid derivatives in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Prostaglandin D2-induced potentiation of hexobarbitone hypnosis in rats: role of 5-hydroxytryptamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Barbital alteration of central nervous system sensitivity to hexobarbital in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Effect of water and food deprivation on hepatic microsomal metabolism of hexobarbital and aniline

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Effect of carbon monoxide inhalation exposure in mice on drug metabolism in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Effect of aromatic nitro compounds on oxidative metabolism by cytochrome P-450 dependent enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Commentary: a physiological approach to hepatic drug clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Induction of microsomal drug-metabolizing enzymes caused by hexobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Hexobarbital disposition in compensated and decompensated cirrhosis of the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Comparative metabolism of benzo[a]pyrene and drugs in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Correlation between the metabolism of hexobarbital and aminopyrine in vivo in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

Effect of Hypophysectomy and Cyproterone Acetate on the Liver Ultrastructure as well as on Hexobarbital Anesthesia and Zoxazolamine Paralysis in Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

The Use of Capillary Columns for the Detection of Barbiturates in Clinical Chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538809049621

10.3109/03602538809049621

21 January 2018

Identifiers

DOI

0 references

1 reference