(Q39567115)

13 September 2017

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title

Lovastatin. A preliminary review of its pharmacodynamic properties and therapeutic use in hyperlipidaemia (English)

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13 September 2017

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J M Henwood

1

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PubMed ID

3069436

13 September 2017

R C Heel

series ordinal

2

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13 September 2017

1 October 1988

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13 September 2017

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13 September 2017

36

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13 September 2017

429-454

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13 September 2017

4

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https://scigraph.springernature.com/pub.10.2165/00003495-198836040-00003

13 September 2017

0 references

cites work

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12 December 2020

The effects of mevinolin on serum cholesterol levels of rabbits with endogenous hypercholesterolemia

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12 December 2020

The clinical efficacy and safety of lovastatin and MK-733--an overview

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12 December 2020

ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium

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12 December 2020

Treatment of primary moderate hypercholesterolemia with lovastatin (mevinolin) and colestipol

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12 December 2020

Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus

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12 December 2020

Lipoprotein receptors in the liver. Control signals for plasma cholesterol traffic

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12 December 2020

Fat transport in lipoproteins--an integrated approach to mechanisms and disorders

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12 December 2020

Effects of ML-236B on cholesterol metabolism in mice and rats: lack of hypocholesterolemic activity in normal animals

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12 December 2020

Inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase by mevinolin in familial hypercholesterolemia heterozygotes: effects on cholesterol balance

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12 December 2020

Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat livers

1 reference

12 December 2020

Bile acid secretion by cultured rat hepatocytes. Regulation by cholesterol availability

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12 December 2020

Influence of combined therapy with mevinolin and interruption of bile-acid reabsorption on low density lipoproteins in heterozygous familial hypercholesterolemia

1 reference

12 December 2020

Cholesterol-lowering effect of mevinolin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme a reductase, in healthy volunteers

1 reference

12 December 2020

Plasma mevalonate as a measure of cholesterol synthesis in man

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12 December 2020

The regulation of acetoacetyl-CoA synthetase activity by modulators of cholesterol synthesis in vivo and the utilization of acetoacetate for cholesterogenesis

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12 December 2020

The influence of mevinolin on the adrenal cortical response to corticotropin in heterozygous familial hypercholesterolemia

1 reference

12 December 2020

Myolysis and acute renal failure in a heart-transplant recipient receiving lovastatin

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12 December 2020

Normal cholesterol levels with lovastatin (mevinolin) therapy in a child with homozygous familial hypercholesterolemia following liver transplantation

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12 December 2020

Therapeutic response to lovastatin (mevinolin) in nonfamilial hypercholesterolemia. A multicenter study. The Lovastatin Study Group II

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12 December 2020

Lovastatin (mevinolin) in the treatment of heterozygous familial hypercholesterolemia. A multicenter study

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12 December 2020

Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase

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12 December 2020

Sorting signals and cellular membranes

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12 December 2020

The mechanism of action of lipid-lowering drugs

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12 December 2020

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent

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12 December 2020

Efficacy of mevinolin as adjuvant therapy for refractory familial hypercholesterolaemia

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12 December 2020

Complementarity of colestipol, niacin, and lovastatin in treatment of severe familial hypercholesterolemia

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12 December 2020

A multicenter comparison of lovastatin and cholestyramine therapy for severe primary hypercholesterolemia. The Lovastatin Study Group III

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12 December 2020

Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth

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12 December 2020

Alterations in the rates of synthesis and degradation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase produced by cholestyramine and mevinolin

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12 December 2020

Hypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia

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12 December 2020

Monacolin K, a new hypocholesterolemic agent produced by a Monascus species.

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12 December 2020

Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. The Expert Panel

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12 December 2020

Mevinolin and cholestyramine inhibit the direct synthesis of low density lipoprotein apolipoprotein B in miniature pigs

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12 December 2020

Long term administration of lovastatin in the treatment of hypercholesterolaemia

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12 December 2020

Rhabdomyolysis in patients receiving lovastatin after cardiac transplantation

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12 December 2020

The effect of mevinolin on steroidogenesis in patients with defects in the low density lipoprotein receptor pathway

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12 December 2020

Lovastatin: follow-up ophthalmologic data

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12 December 2020

The effects of mevinolin and neomycin alone and in combination on plasma lipid and lipoprotein concentrations in type II hyperlipoproteinemia

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12 December 2020

Inhibition of cholesterol synthesis by mevinolin stimulates low density lipoprotein receptor activity in human monocyte-derived macrophages

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12 December 2020

Bile acid synthesis by cultured hepatocytes. Inhibition by mevinolin, but not by bile acids

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12 December 2020

Rapid and substantial lowering of human serum cholesterol by mevinolin (MK-803), an inhibitor of hydroxymethylglutaryl-coenzyme A reductase

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12 December 2020

Influence of mevinolin on experimental atherosclerosis in rabbits

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12 December 2020

Comparative efficacy of once versus twice daily mevinolin in the therapy of familial hypercholesterolemia

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12 December 2020

Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (beta) lipoproteins]

1 reference

12 December 2020

Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes

1 reference

12 December 2020

Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia

1 reference

12 December 2020

Regulation of hepatic receptor-dependent degradation of LDL by mevinolin in rabbits with hypercholesterolemia induced by a wheat starch-casein diet

1 reference

12 December 2020

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1 reference

12 December 2020

Treatment of common lipoprotein disorders

1 reference

12 December 2020

Effectiveness of mevinolin on plasma lipoprotein concentrations in type II hyperlipoproteinemia

1 reference

12 December 2020

The effect of cholestyramine and Mevinolin on the diurnal cycle of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase

1 reference

12 December 2020

Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase

1 reference

12 December 2020

Lovastatin for lowering cholesterol levels in non-insulin-dependent diabetes mellitus

1 reference

12 December 2020

Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its mRNA in rat liver as studied with a monoclonal antibody and a cDNA probe.

1 reference

12 December 2020

Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog

1 reference

12 December 2020

Monacolin K, a new hypocholesterolemic agent produced by a Monascus species.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.32.852

Identifiers

DOI

10.2165/00003495-198836040-00003

1 reference

PubMed ID

3069436

Dimensions Publication ID

13 September 2017

0 references

1 reference

PubMed ID

3069436