(Q39586742)

13 September 2017

title

GFAP promoter-driven RNA interference on TGF-β1 to treat liver fibrosis (English)

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13 September 2017

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Ningning Yang

1

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13 September 2017

Ram I Mahato

series ordinal

2

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13 September 2017

publication date

23 February 2011

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13 September 2017

published in

Pharmaceutical Research

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13 September 2017

volume

28

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13 September 2017

issue

4

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13 September 2017

page(s)

752-761

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Mechanisms of hepatic fibrogenesis

13 September 2017

cites work

1 reference

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TGF-beta-induced fibrosis and SMAD signaling: oligo decoys as natural therapeutics for inhibition of tissue fibrosis and scarring

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Liver fibrosis -- from bench to bedside

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In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis

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Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta

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Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat.

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TGF-beta1 gene silencing for treating liver fibrosis

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RNA polymerase II mediated transcription from the polymerase III promoters in short hairpin RNA expression vector

21 January 2018

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The bone marrow functionally contributes to liver fibrosis.

21 January 2018

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GFAP promoter directs lacZ expression specifically in a rat hepatic stellate cell line

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Targeted inhibition of platelet-derived growth factor receptor-beta subunit in hepatic stellate cells ameliorates hepatic fibrosis in rats

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21 January 2018

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21 January 2018

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Coexpression of vascular endothelial growth factor and interleukin-1 receptor antagonist for improved human islet survival and function

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Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation

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Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs

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21 January 2018

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TGF-beta1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases.

21 January 2018

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TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector

21 January 2018

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Transforming growth factor beta 1 induces proliferation in colon carcinoma cells by Ras-dependent, smad-independent down-regulation of p21cip1.

21 January 2018

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Exploring hypotheses of the actions of TGF-beta1 in epidermal wound healing using a 3D computational multiscale model of the human epidermis

21 January 2018

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TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

21 January 2018

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21 January 2018

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12 December 2020

Synthesis, formulation and in vitro evaluation of a novel microtubule destabilizer, SMART-100.

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12 December 2020

Prevention of CCl4-induced liver cirrhosis by ribbon antisense to transforming growth factor-beta1.

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12 December 2020

Loss of TGF-beta dependent growth control during HSC transdifferentiation

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12 December 2020

The bcl, NFkappaB and p53/p21WAF1 systems are involved in spontaneous apoptosis and in the anti-apoptotic effect of TGF-beta or TNF-alpha on activated hepatic stellate cells

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12 December 2020

10.1007/S11095-011-0384-Y

Identifiers

DOI

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13 September 2017

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