(Q39594191)

13 September 2017

XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells (English)

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13 September 2017

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hepatocellular carcinoma

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Yan Liu

1

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13 September 2017

Aiguo Liu

2

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13 September 2017

Zhenghu Xu

3

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13 September 2017

Wenying Yu

4

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13 September 2017

Hong Wang

5

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13 September 2017

Chenglong Li

6

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13 September 2017

Jiayuh Lin

7

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13 September 2017

1 May 2011

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13 September 2017

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13 September 2017

16

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13 September 2017

5

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13 September 2017

502-510

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https://scigraph.springernature.com/pub.10.1007/s10495-011-0578-0

13 September 2017

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cites work

Cancer statistics, 2001

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Inflammation and liver cancer: new molecular links .

21 January 2018

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Hepatocellular carcinoma: epidemiology, risk factors, and screening

21 January 2018

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21 January 2018

Liver cancer on the rise

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21 January 2018

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Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

STATs in cancer inflammation and immunity: a leading role for STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-beta signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Inhibition of growth and metastasis of human hepatocellular carcinoma by antisense oligonucleotide targeting signal transducer and activator of transcription 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Silencing of signal transducer and activator of transcription 3 expression by RNA interference suppresses growth of human hepatocellular carcinoma in tumor-bearing nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Deactivation of Akt and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, Atiprimod

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Stat3 regulates genes common to both wound healing and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Stat3 activation in human endometrial and cervical cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

STAT3 as a central mediator of neoplastic cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

STAT3 is required for the gp130-mediated full activation of the c-myc gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

Epidemiology of Hepatocellular Carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-011-0578-0

10.1007/S10495-011-0578-0

21 January 2018

Identifiers

DOI

1 reference

13 September 2017

1 reference