(Q39602224)

English

Interleukin-6 enhances glucose-stimulated insulin secretion from pancreatic beta-cells: potential involvement of the PLC-IP3-dependent pathway

scientific article published on February 2011

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

Interleukin-6 enhances glucose-stimulated insulin secretion from pancreatic beta-cells: potential involvement of the PLC-IP3-dependent pathway (English)

1 reference

Europe PubMed Central

13 September 2017

1 reference

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author name string

Toshinobu Suzuki

1

1 reference

Europe PubMed Central

13 September 2017

Junta Imai

2

1 reference

Europe PubMed Central

13 September 2017

Tetsuya Yamada

3

1 reference

Europe PubMed Central

13 September 2017

Yasushi Ishigaki

4

1 reference

Europe PubMed Central

13 September 2017

Keizo Kaneko

5

1 reference

Europe PubMed Central

13 September 2017

Kenji Uno

6

1 reference

Europe PubMed Central

13 September 2017

Yutaka Hasegawa

7

1 reference

Europe PubMed Central

13 September 2017

Hisamitsu Ishihara

8

1 reference

Europe PubMed Central

13 September 2017

Yoshitomo Oka

9

1 reference

Europe PubMed Central

13 September 2017

Hideki Katagiri

10

1 reference

Europe PubMed Central

13 September 2017

language of work or name

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publication date

1 February 2011

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Europe PubMed Central

13 September 2017

number of pages

11

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inferred from page(s)

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Europe PubMed Central

13 September 2017

60

1 reference

Europe PubMed Central

13 September 2017

2

1 reference

Europe PubMed Central

13 September 2017

537-547

1 reference

Europe PubMed Central

13 September 2017

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

30 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes

1 reference

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Interleukin-6 regulates pancreatic alpha-cell mass expansion

1 reference

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The role of interleukin-6 in insulin resistance, body fat distribution and energy balance

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Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk

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Interleukin-6 and diabetes: the good, the bad, or the indifferent?

1 reference

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14 September 2017

Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release

1 reference

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1 reference

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Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

1 reference

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14 September 2017

Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells

1 reference

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Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function

1 reference

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Structure, function, and control of phosphoinositide-specific phospholipase C

1 reference

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Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors

1 reference

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14 September 2017

IL-6 protects pancreatic islet beta cells from pro-inflammatory cytokines-induced cell death and functional impairment in vitro and in vivo

1 reference

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14 September 2017

Glucagon-like peptide-1 inhibits pancreatic ATP-sensitive potassium channels via a protein kinase A- and ADP-dependent mechanism

1 reference

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25 September 2017

Interleukin-6 increases insulin secretion and preproinsulin mRNA expression via Ca2+-dependent mechanism

1 reference

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Passage of cytokines across the blood-brain barrier

1 reference

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25 September 2017

Interleukin-6 and tumor necrosis factor-alpha are not increased in patients with Type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness.

1 reference

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Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes

1 reference

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Overexpression of catalytic subunit p110alpha of phosphatidylinositol 3-kinase increases glucose transport activity with translocation of glucose transporters in 3T3-L1 adipocytes

1 reference

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Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets

1 reference

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Early changes in postprandial insulin secretion, not in insulin sensitivity, characterize juvenile obesity.

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Dynamics of pancreatic insulin release in young Zucker rats: a heterozygote effect

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Inhibition of insulin secretion from rat islets of Langerhans by interleukin-6. An effect distinct from that of interleukin-1.

1 reference

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Regulation of pancreatic beta cell mass by neuronal signals from the liver.

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Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice.

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Plasma interleukin-6 levels are independently associated with insulin secretion in a cohort of Italian-Caucasian nondiabetic subjects.

1 reference

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Increased plasma interleukin-6 is associated with the pathogenesis of obstructive sleep apnea syndrome.

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Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion

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Interleukin-6-deficient mice develop mature-onset obesity

1 reference

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Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/21270264

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 6: A Functional and Structuralin VitroModulator of Beta-Cells from Islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21270264

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic interaction of glucose and neurohumoral agonists to stimulate islet phosphoinositide hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21270264

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of G11alpha and isoforms of phospholipase C in islet beta-cells reveals a lack of correlation between inositol phosphate accumulation and insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/21270264

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21270264

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cold exposure suppresses serum adiponectin levels through sympathetic nerve activation in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21270264

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21270264

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB10-0796

1 reference

Europe PubMed Central

13 September 2017

Internet Archive ID

pubmed-PMC3028353

0 references

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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