(Q39604426)

13 September 2017

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title

Relationship of pharmacokinetic and pharmacodynamic properties of the organic nitrates (English)

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13 September 2017

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U Thadani

1

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PubMed ID

3135973

13 September 2017

T Whitsett

series ordinal

2

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13 September 2017

1 July 1988

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Clinical Pharmacokinetics

13 September 2017

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13 September 2017

15

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13 September 2017

1

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13 September 2017

32-43

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https://scigraph.springernature.com/pub.10.2165/00003088-198815010-00003

13 September 2017

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cites work

[Rapid attenuation of effects of isosorbide dinitrate during long-term treatment of chronic congestive heart failure]

1 reference

12 December 2020

The effects of moderate sustained exercise on the pharmacokinetics of nitroglycerine

1 reference

12 December 2020

Pharmacokinetic-hemodynamic studies of transdermal nitroglycerin in congestive heart failure

1 reference

12 December 2020

Intraoperative coronary collateral function in patients with coronary occlusive disease. Nitroglycerin responsiveness and angiographic correlations.

1 reference

12 December 2020

Nitroglycerin revisited: chemistry, biochemistry, interactions

1 reference

12 December 2020

Isosorbide 5-mononitrate and isosorbide 2-mononitrate kinetics after intravenous and oral dosing

1 reference

12 December 2020

Tolerance to the vascular effects of glyceryl trinitrate

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12 December 2020

Isosorbide 5-mononitrate kinetics

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12 December 2020

Duration of effects and tolerance of slow-release isosorbide-5-mononitrate for angina pectoris

1 reference

12 December 2020

Transdermal isosorbide dinitrate in angina pectoris: effect of acute and sustained therapy

1 reference

12 December 2020

Effects of isosorbide-5-mononitrate on exercise-induced hemodynamic changes in angina pectoris

1 reference

12 December 2020

Usefulness of twice-daily isosorbide-5-mononitrate in preventing development of tolerance in angina pectoris

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12 December 2020

Hemodynamic changes at rest and during stress following isosorbide-5-mononitrate therapy in patients with coronary disease

1 reference

12 December 2020

Nitrate therapy in stable angina pectoris

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12 December 2020

Nitrates for angina pectoris. A critical review of therapeutic efficacy and tolerance

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12 December 2020

Improved exercise capacity and differing arterial and venous tolerance during chronic isosorbide dinitrate therapy for congestive heart failure

1 reference

12 December 2020

Nitrate tolerance: a clinically significant problem?

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12 December 2020

Pharmacokinetic determinants of nitrate action

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12 December 2020

Nitroglycerin Pharmacokinetics After Intravenous Infusion in Normal Subjects

1 reference

12 December 2020

Dose dependence of tolerance during treatment with mononitrates

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12 December 2020

Mechanism of tolerance development to organic nitrates

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12 December 2020

Dose-response relation of antianginal activity of isosorbide dinitrate

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12 December 2020

Transdermal nitroglycerin patches in angina pectoris. Dose titration, duration of effect, and rapid tolerance

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12 December 2020

Cyclic guanosine monophosphate as a mediator of vasodilation

1 reference

12 December 2020

Transdermal nitroglycerin and nitrate tolerance

1 reference

12 December 2020

Relation of time course of plasma nitroglycerin levels to echocardiographic, arterial pressure and heart rate changes after sublingual administration of nitroglycerin

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12 December 2020

The effects of nitroglycerin on cyclic nucleotides in the coronary artery in vivo

1 reference

12 December 2020

Fate of orally given isosorbide dinitrate in man: factors of variability

1 reference

12 December 2020

Oral isosorbide dinitrate in angina pectoris: comparison of duration of action an dose-response relation during acute and sustained therapy

1 reference

12 December 2020

Sustained hemodynamic effects without tolerance during long-term isosorbide dinitrate treatment of chronic left ventricular failure

1 reference

12 December 2020

The nitroglycerin polymer gel matrix system: a new method for administering nitroglycerin evaluated with plasma nitroglycerin levels

1 reference

12 December 2020

In vivo induction and reversal of nitroglycerin tolerance in human coronary arteries

1 reference

12 December 2020

Hemodynamic effect, effect duration and pharmacokinetics of 80 mg of isosorbide-5-mononitrate in acute myocardial infarct

1 reference

12 December 2020

Tolerance towards glyceryl trinitrate (trinitrin) in dogs

1 reference

12 December 2020

The clinical use of transdermal delivery devices with nitroglycerin

1 reference

12 December 2020

Isosorbide dinitrate. Effect on the vasodilator response to nitroglycerin

1 reference

12 December 2020

Pharmacokinetic-hemodynamic studies of intravenous nitroglycerin in congestive cardiac failure.

1 reference

12 December 2020

Hemodynamic and hormonal response to transdermal nitroglycerin in normal subjects and in patients with congestive heart failure

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12 December 2020

Requirement of thiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite possible involvement of S-nitrosothiols

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of isosorbide dinitrate.

1 reference

12 December 2020

The bioavailability of oral nitroglycerin

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12 December 2020

Plasma nitroglycerin levels after sublingual, oral and topical administration

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12 December 2020

Effect of a new transdermal therapeutic system containing nitroglycerin on exercise capacity in patients with angina pectoris

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12 December 2020

Induction and circumvention of nitrate tolerance applying different dosage intervals

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12 December 2020

Mechanism of nitrate-induced vasodilation and tolerance

1 reference

12 December 2020

Anti-anginal and anti-ischemic efficacy of conventional and slow release formulations of isosorbide-5-mononitrate in angina pectoris

1 reference

12 December 2020

Isosorbide-5-mononitrate in angina pectoris: plasma concentrations and duration of effects after acute therapy

1 reference

12 December 2020

Determination of nitroglycerin and its dinitrate metabolites in human plasma by high-performance liquid chromatography with thermal energy analyzer detection

1 reference

12 December 2020

Tolerance to the circulatory effects of oral isosorbide dinitrate. Rate of development and cross-tolerance to glyceryl trinitrate

1 reference

12 December 2020

Rapidly developing tolerance to transdermal nitroglycerin in congestive heart failure

1 reference

12 December 2020

Isosorbide dinitrate and glyceryl trinitrate: demonstration of cross tolerance in the capacitance vessels

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12 December 2020

1 reference

12 December 2020

Isosorbide dinitrate kinetics and dynamics after intravenous, sublingual, and percutaneous dosing in angina

1 reference

12 December 2020

Incomplete and delayed bioavailability of sublingual nitroglycerin

1 reference

12 December 2020

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates

1 reference

12 December 2020

Effect of dose and ointment application technique on nitroglycerin plasma concentrations

1 reference

12 December 2020

Altered spectrum of nitroglycerin action in long-term treatment: nitroglycerin-specific venous tolerance with maintenance of arterial vasodepressor potency.

1 reference

12 December 2020

Transdermal nitroglycerin in angina pectoris

1 reference

12 December 2020

The effect of food on the oral absorption of isosorbide-5-mononitrate

1 reference

12 December 2020

The effectiveness of transcutaneous nitrate preparations for angina pectoris

1 reference

12 December 2020

Sustained beneficial hemodynamic responses to large doses of transdermal nitroglycerin in congestive heart failure and comparison with intravenous nitroglycerin

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12 December 2020

Role of the liver in the disposition of intravenous nitroglycerin in the rat.

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12 December 2020

Clinical pharmacokinetics of glyceryl trinitrate following the use of systemic and topical preparations

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12 December 2020

Influence of posture on plasma nitroglycerin

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12 December 2020

GLC determination of nitroglycerin and isosorbide dinitrate in human plasma

1 reference

12 December 2020

Isosorbide 5‐mononitrate pharmacokinetics in humans

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12 December 2020

Fate of isosorbide dinitrate and mononitrates in patients with renal failure

1 reference

12 December 2020

Kinetics of isosorbide dinitrate and relationships to pharmacological effects

1 reference

12 December 2020

Steady state kinetics of isosorbide-5-mononitrate in patients with coronary disease

1 reference

12 December 2020

Blood levels after sublingual nitroglycerin

1 reference

12 December 2020

Prevention and reversal of nitrate tolerance in patients with congestive heart failure

1 reference

12 December 2020

Oral isosorbide dinitrate in the treatment of angina pectoris. Dose-response relationship and duration of action during acute therapy

1 reference

12 December 2020

Isosorbide 5-mononitrate pharmacokinetics

1 reference

12 December 2020

Tolerance towards glyceryltrinitrate (trinitrin) in rabbits

1 reference

12 December 2020

Oral isosorbide-5-mononitrate: pharmacokinetics and clinical efficacy

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12 December 2020

Dose dependent pharmacokinetics of nitroglycerin after multiple intravenous infusions in healthy volunteers

1 reference

12 December 2020

Pharmacokinetics and metabolism of isosorbide-dinitrate after intravenous and oral administration

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12 December 2020

Plasma concentrations and haemodynamic effects of nitroglycerin during and after intravenous infusion in healthy volunteers

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12 December 2020

Tolerance towards nitroglycerin, induced in vivo, is correlated to a reduced cGMP response and an alteration in cGMP turnover

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12 December 2020

Effect of intervals between doses on the development of tolerance to isosorbide dinitrate

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12 December 2020

The mechanism of cGMP-induced relaxation in vascular smooth muscle

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12 December 2020

Hemodynamic measurements and exercise testing to assess the development of tolerance against slow-release isosorbide dinitrate

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12 December 2020

Clinical pharmacokinetics of organic nitrates

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12 December 2020

Magnitude of dilatation of large and small coronary arteries of nitroglycerin

1 reference

12 December 2020

Analysis, disposition and pharmacokinetics of nitroglycerin

1 reference

12 December 2020

10.2165/00003088-198815010-00003

Identifiers

DOI

1 reference

PubMed ID

3135973

Dimensions Publication ID

13 September 2017

0 references

1 reference

PubMed ID

3135973