(Q39605336)

English

Evidence for common structural determinants of human immunodeficiency virus type 1 coreceptor activity provided through functional analysis of CCR5/CXCR4 chimeric coreceptors

scientific article published on December 2001

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

Evidence for common structural determinants of human immunodeficiency virus type 1 coreceptor activity provided through functional analysis of CCR5/CXCR4 chimeric coreceptors (English)

1 reference

Europe PubMed Central

13 September 2017

author name string

Pontow S

1

1 reference

Europe PubMed Central

13 September 2017

Ratner L

2

1 reference

Europe PubMed Central

13 September 2017

language of work or name

0 references

publication date

1 December 2001

1 reference

Europe PubMed Central

13 September 2017

Journal of Virology

1 reference

Europe PubMed Central

13 September 2017

75

1 reference

Europe PubMed Central

13 September 2017

11503-11514

1 reference

Europe PubMed Central

13 September 2017

23

1 reference

Europe PubMed Central

13 September 2017

Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor

1 reference

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14 September 2017

Beyond receptor expression: the influence of receptor conformation, density, and affinity in HIV-1 infection

1 reference

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14 September 2017

HIV-1 membrane fusion: targets of opportunity

1 reference

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14 September 2017

A biosensor assay for studying ligand-membrane receptor interactions: binding of antibodies and HIV-1 Env to chemokine receptors

1 reference

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14 September 2017

Inhibition of HIV infection by bicyclams, highly potent and specific CXCR4 antagonists

1 reference

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14 September 2017

N-linked glycosylation of CXCR4 masks coreceptor function for CCR5-dependent human immunodeficiency virus type 1 isolates

1 reference

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14 September 2017

Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease

1 reference

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14 September 2017

Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.

1 reference

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14 September 2017

Relationship between productive HIV-1 infection of macrophages and CCR5 utilization

1 reference

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14 September 2017

CCR5 HIV-1 coreceptor activity. Role of cooperativity between residues in N-terminal extracellular and intracellular domains

1 reference

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14 September 2017

Analysis of the critical domain in the V3 loop of human immunodeficiency virus type 1 gp120 involved in CCR5 utilization

1 reference

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14 September 2017

Mutagenesis of CXCR4 identifies important domains for human immunodeficiency virus type 1 X4 isolate envelope-mediated membrane fusion and virus entry and reveals cryptic coreceptor activity for R5 isolates

1 reference

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14 September 2017

HIV and SIV gp120 binding does not predict coreceptor function

1 reference

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14 September 2017

Constitutive cell surface association between CD4 and CCR5.

1 reference

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14 September 2017

Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 and prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4

1 reference

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14 September 2017

Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease

1 reference

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14 September 2017

Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants.

1 reference

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14 September 2017

Identification of CXCR4 domains that support coreceptor and chemokine receptor functions

1 reference

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14 September 2017

Effect of mutations in the second extracellular loop of CXCR4 on its utilization by human and feline immunodeficiency viruses.

1 reference

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14 September 2017

Determinants for sensitivity of human immunodeficiency virus coreceptor CXCR4 to the bicyclam AMD3100

1 reference

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14 September 2017

CXCR4 sequences involved in coreceptor determination of human immunodeficiency virus type-1 tropism. Unmasking of activity with M-tropic Env glycoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114737

14 September 2017

T-cell-line-tropic human immunodeficiency virus type 1 that is made resistant to stromal cell-derived factor 1alpha contains mutations in the envelope gp120 but does not show a switch in coreceptor use

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114737

14 September 2017

Alanine substitutions of polar and nonpolar residues in the amino-terminal domain of CCR5 differently impair entry of macrophage- and dualtropic isolates of human immunodeficiency virus type 1.

1 reference

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14 September 2017

A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5

1 reference

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14 September 2017

Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry

1 reference

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14 September 2017

In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression.

1 reference

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14 September 2017

Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses

1 reference

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14 September 2017

Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding

1 reference

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14 September 2017

HIV-1 gp120 induces an association between CD4 and the chemokine receptor CXCR4.

1 reference

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14 September 2017

Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.

1 reference

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14 September 2017

Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains

1 reference

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14 September 2017

Role of the first and third extracellular domains of CXCR-4 in human immunodeficiency virus coreceptor activity

1 reference

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14 September 2017

Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity

1 reference

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14 September 2017

HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5.

1 reference

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14 September 2017

Change in coreceptor use correlates with disease progression in HIV-1--infected individuals

1 reference

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Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity

1 reference

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

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Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation.

1 reference

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Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes

1 reference

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Changing virus-host interactions in the course of HIV-1 infection.

1 reference

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Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses.

1 reference

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The HTLV receptor is a widely expressed protein

1 reference

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25 September 2017

Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function

1 reference

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25 September 2017

CC chemokine receptor 5-mediated signaling and HIV-1 Co-receptor activity share common structural determinants. Critical residues in the third extracellular loop support HIV-1 fusion

1 reference

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25 September 2017

Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines

1 reference

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25 September 2017

A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry

1 reference

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21 August 2018

Entry of R5X4 and X4 human immunodeficiency virus type 1 strains is mediated by negatively charged and tyrosine residues in the amino-terminal domain and the second extracellular loop of CXCR4.

1 reference

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21 August 2018

Substitutions in a homologous region of extracellular loop 2 of CXCR4 and CCR5 alter coreceptor activities for HIV-1 membrane fusion and virus entry

1 reference

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21 August 2018

Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities

1 reference

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21 August 2018

Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

1 reference

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21 August 2018

The amino terminus of human CCR5 is required for its function as a receptor for diverse human and simian immunodeficiency virus envelope glycoproteins

1 reference

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21 August 2018

Identifiers

10.1128/JVI.75.23.11503-11514.2001

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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