(Q39607399)

English

Enhanced flexibility and aphidicolin-induced DNA breaks near mammalian replication origins: implications for replicon mapping and chromosome fragility

scientific article published on December 2000

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

Enhanced flexibility and aphidicolin-induced DNA breaks near mammalian replication origins: implications for replicon mapping and chromosome fragility (English)

1 reference

Europe PubMed Central

13 September 2017

author name string

Toledo F

1

1 reference

Europe PubMed Central

13 September 2017

Coquelle A

2

1 reference

Europe PubMed Central

13 September 2017

Svetlova E

3

1 reference

Europe PubMed Central

13 September 2017

Debatisse M

4

1 reference

Europe PubMed Central

13 September 2017

language of work or name

0 references

publication date

1 December 2000

1 reference

Europe PubMed Central

13 September 2017

Nucleic Acids Research

1 reference

Europe PubMed Central

13 September 2017

28

1 reference

Europe PubMed Central

13 September 2017

4805-4813

1 reference

Europe PubMed Central

13 September 2017

23

1 reference

Europe PubMed Central

13 September 2017

Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Hemicatenanes form upon inhibition of DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Replication fork pausing and recombination or "gimme a break"

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Replication origins of mammalian chromosomes: the happy few.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Cancer-specific chromosome alterations in the constitutive fragile region FRA3B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Initiation of DNA replication at the Chinese hamster origin oriGNAI3 relies on local sequences and/or chromatin structures, but not on transcription of the nearby GNAI3 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Replication origins in metazoan chromosomes: fact or fiction?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Instability at chromosomal fragile sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Identification of primary initiation sites for DNA replication in the hamster dihydrofolate reductase gene initiation zone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

oriGNAI3: a narrow zone of preferential replication initiation in mammalian cells identified by 2D gel and competitive PCR replicon mapping techniques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Matrix attachment regions and transcription units in a polygenic mammalian locus overlapping two isochores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Replication initiation and elongation fork rates within a differentially expressed human multicopy locus in early S phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Mathematical model to predict regions of chromatin attachment to the nuclear matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

High-resolution mapping of the origin of DNA replication in the hamster dihydrofolate reductase gene domain by competitive PCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

A 350-kb cosmid contig in 3p14.2 that crosses the t(3;8) hereditary renal cell carcinoma translocation breakpoint and 17 aphidicolin-induced FRA3B breakpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Initiation and termination of DNA replication in human rRNA genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Fine mapping of a replication origin of human DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Modular sequence elements associated with origin regions in eukaryotic chromosomal DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Mapping of replication initiation sites in human ribosomal DNA by nascent-strand abundance analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Structure and variation of human ribosomal DNA: the external transcribed spacer and adjacent regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Nonuniform recombination within the human beta-globin gene cluster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Segregation and rearrangement of coamplified genes in different lineages of mutant cells that overproduce adenylate deaminase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

A molecular basis for discrete size variation in human ribosomal DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Replication in the amplified dihydrofolate reductase domain in CHO cells may initiate at two distinct sites, one of which is a repetitive sequence element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Replication initiates in a broad zone in the amplified CHO dihydrofolate reductase domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

DNA amplification is rare in normal human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

A human DNA replication origin: localization and transcriptional characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

14 September 2017

The role of deletions at the FRA3B/FHIT locus in carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

25 September 2017

Allele-specific late replication and fragility of the most active common fragile site, FRA3B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

25 September 2017

DNA replication origin and transcriptional enhancer in c-myc gene share the c-myc protein binding sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

25 September 2017

A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

25 September 2017

Genetic dissection of a mammalian replicator in the human beta-globin locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

25 September 2017

Direct cloning and analysis of DNA sequences from a region of the Chinese hamster genome associated with aphidicolin-sensitive fragility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

25 September 2017

The multicopy appearance of a large inverted duplication and the sequence at the inversion joint suggest a new model for gene amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

25 September 2017

Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

25 September 2017

The highly conserved Chinese hamster GNAI3 gene maps less than 60 kb from the AMPD2 gene and lacks the intronic U6 snRNA present in its human counterpart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

25 September 2017

A hotspot for novel amplification joints in a mosaic of Alu-like repeats and palindromic A + T-rich DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

25 September 2017

Mapping of replication initiation sites in the mouse ribosomal gene cluster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

15 June 2018

Replication structure of the human beta-globin gene domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

15 June 2018

Constitutive fragile sites and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

15 June 2018

Sequence dependence of DNA conformational flexibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

15 June 2018

Identification of an origin of bidirectional DNA replication in mammalian chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

15 June 2018

A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

15 June 2018

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

15 June 2018

The evolution of the amplified adenylate deaminase 2 domains in Chinese hamster cells suggests the sequential operation of different mechanisms of DNA amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

15 June 2018

The origin of chromosome rearrangements at early stages of AMPD2 gene amplification in Chinese hamster cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

21 August 2018

Selection and mapping of replication origins from a 500-kb region of the human X chromosome and their relationship to gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

21 August 2018

Common fragile sites: G-band characteristics within an R-band

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

21 August 2018

Initiation of DNA replication at CpG islands in mammalian chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

21 August 2018

A distamycin A-inducible fragile site, FRA8E, located in the region of the hereditary multiple exostoses gene, is not involved in HPV16 DNA integration and amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

21 August 2018

Mapping of replication origins and termination sites in the Duchenne muscular dystrophy gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

21 August 2018

Aphidicolin-induced FRA3B breakpoints cluster in two distinct regions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

21 August 2018

Chinese hamster transducin gene (GNAT2): genomic organization and peptide conservation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

21 August 2018

Meiotic recombination in an Irish family with beta-thalassaemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=115181

21 August 2018

Multiple initiations in the c-myc replication origin independent of chromosomal location

1 reference

https://pubmed.ncbi.nlm.nih.gov/11095694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping replication units in animal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11095694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/11095694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of DNA replication in isolated nuclei initiated by an aprotinin-binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/11095694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fragile sites still breaking

1 reference

https://pubmed.ncbi.nlm.nih.gov/11095694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11095694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the sites of initiation of DNA replication in rat and human rRNA genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11095694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombination breakpoints in the human beta-globin gene cluster

1 reference

https://pubmed.ncbi.nlm.nih.gov/11095694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/28.23.4805

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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