(Q39612525)

English

Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway

scientific article published on March 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

lipopolysaccharide

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author name string

Abedul Haque

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Naoki Koide

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Imtiaz Iftakhar-E-Khuda

3

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Abu Shadat Mohammod Noman

4

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Erdenezaya Odkhuu

5

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Battuvshin Badamtseren

6

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Yoshikazu Naiki

7

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Takayuki Komatsu

8

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Tomoaki Yoshida

9

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Takashi Yokochi

10

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

publication date

1 March 2011

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Europe PubMed Central

PubMed publication ID

13 September 2017

Microbiology and Immunology

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Europe PubMed Central

PubMed publication ID

13 September 2017

55

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Europe PubMed Central

PubMed publication ID

13 September 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

160-167

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances ap

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

A Phase II Study of Flavopiridol in Patients With Previously Untreated Advanced Soft Tissue Sarcoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Phase I dose-finding study of weekly docetaxel followed by flavopiridol for patients with advanced solid tumors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Role of adapters in Toll-like receptor signalling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Astrocyte elevated gene-1 (AEG-1) is induced by lipopolysaccharide as toll-like receptor 4 (TLR4) ligand and regulates TLR4 signalling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Interleukin 1 (IL1) and tumour necrosis factor (TNF) signal transduction

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

TRAF6 is a signal transducer for interleukin-1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

TLR4/MyD88/PI3K interactions regulate TLR4 signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Requirement for transcription factor IRF-1 in NO synthase induction in macrophages.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Suppression of interleukin-1beta-induced nitric-oxide synthase promoter/enhancer activity by transforming growth factor-beta1 in vascular smooth muscle cells. Evidence for mechanisms other than NF-kappaB.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

MyD88 functions as a negative regulator of TLR3/TRIF-induced corneal inflammation by inhibiting activation of c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

TNF-alpha as a therapeutic target in inflammatory diseases, ischemia-reperfusion injury and trauma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Role of nitric oxide in inflammatory diseases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Design, synthesis, and antiproliferative and CDK2-cyclin a inhibitory activity of novel flavopiridol analogues.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

The inhibitory action of quercetin on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2010.00304.X

21 January 2018

Identifiers

10.1111/J.1348-0421.2010.00304.X

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

ResearchGate publication ID

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