(Q39634357)

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Identification and characterization of persistent intracellular human immunodeficiency virus type 1 integrase strand transfer inhibitor activity

scientific article published on 8 November 2010

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scholarly article

1 reference

Europe PubMed Central

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16 January 2020

Identification and characterization of persistent intracellular human immunodeficiency virus type 1 integrase strand transfer inhibitor activity (English)

1 reference

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16 January 2020

2

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16 January 2020

author name string

Yasuhiro Koh

1

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16 January 2020

Alan Engelman

3

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16 January 2020

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publication date

8 November 2010

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16 January 2020

Antimicrobial Agents and Chemotherapy

1 reference

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16 January 2020

55

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16 January 2020

1

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16 January 2020

42-49

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Europe PubMed Central

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16 January 2020

Antiretroviral therapy in the clinic

1 reference

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14 September 2017

Assessment of the susceptibility of mutant HIV-1 to antiviral agents

1 reference

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Synchronous infection of SIV and HIV in vitro for virology, immunology and vaccine-related studies

1 reference

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14 September 2017

Strand transfer inhibitors of HIV-1 integrase: bringing IN a new era of antiretroviral therapy

1 reference

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Comparative biochemical analysis of HIV-1 subtype B and C integrase enzymes.

1 reference

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Structural basis for functional tetramerization of lentiviral integrase

1 reference

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Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain

1 reference

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HIV pathogenesis: 25 years of progress and persistent challenges

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Preclinical evaluation of 1H-benzylindole derivatives as novel human immunodeficiency virus integrase strand transfer inhibitors

1 reference

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Mutations in human immunodeficiency virus type 1 integrase confer resistance to the naphthyridine L-870,810 and cross-resistance to the clinical trial drug GS-9137.

1 reference

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14 September 2017

Human macrophages support persistent transcription from unintegrated HIV-1 DNA.

1 reference

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Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4'-ethynyl-2-fluoro-2'-deoxyadenosine

1 reference

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14 September 2017

Characterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitors

1 reference

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14 September 2017

Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuli

1 reference

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Pharmacokinetic properties of nucleoside/nucleotide reverse transcriptase inhibitors

1 reference

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Sensitive enzyme immunoassay for measuring plasma and intracellular nevirapine levels in human immunodeficiency virus-infected patients

1 reference

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14 September 2017

Molecular characterization of preintegration latency in human immunodeficiency virus type 1 infection

1 reference

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14 September 2017

A tight-binding mode of inhibition is essential for anti-human immunodeficiency virus type 1 virucidal activity of nonnucleoside reverse transcriptase inhibitors

1 reference

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Clinical pharmacokinetics of non-nucleoside reverse transcriptase inhibitors

1 reference

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14 September 2017

Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

1 reference

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Human immunodeficiency virus type 1 replication in the absence of integrase-mediated dna recombination: definition of permissive and nonpermissive T-cell lines

1 reference

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14 September 2017

HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

1 reference

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14 September 2017

Intracellular metabolism of CycloSaligenyl 3'-azido-2', 3'-dideoxythymidine monophosphate, a prodrug of 3'-azido-2', 3'-dideoxythymidine (zidovudine).

1 reference

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14 September 2017

L-743, 726 (DMP-266): a novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase

1 reference

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14 September 2017

Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine

1 reference

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The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1 reference

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3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro

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14 September 2017

Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor

1 reference

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Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

1 reference

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14 September 2017

Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event

1 reference

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14 September 2017

Human immunodeficiency virus type 1 tropism for human macrophages

1 reference

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1 reference

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14 September 2017

Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replication

1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

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Identifiers

10.1128/AAC.01064-10

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Europe PubMed Central

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16 January 2020

1 reference

Europe PubMed Central

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16 January 2020

1 reference

Europe PubMed Central

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16 January 2020

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